Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence
Keywords: Epigenetic regulation; ROS; IFN-γ; HDACi; Choriocarcinoma; MHC
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Histone deacetylase inhibitors as a new weapon in the arsenal of differentiation therapies of cancer
Keywords: HDACs; HDACi; Differentiation; Cancer
Chemotherapeutic Drug-Induced ABCG2 Promoter Demethylation as a Novel Mechanism of Acquired Multidrug Resistance
Keywords: ABC; ATP-binding cassette; Act D; actinomycin D; ALL; acute lymphoblastic leukemia; COBRA; combined bisulfite restriction analysis; DNMT; DNA methyltransferase; DNR; daunorubicin; Dox; doxorubicin; FTC; fumitremorgin C; HDACi; histone deacetylase inhibito
ZEB-1, a Repressor of the Semaphorin 3F Tumor Suppressor Gene in Lung Cancer Cells
Keywords: CAM; chorioallantoic membrane; ChIP; chromatin immunoprecipitation; Dox; doxycycline; E-Cad; E-Cadherin; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitor; HIF;
Chemically distinct HDAC inhibitors prevent adipose conversion of subcutaneous human white preadipocytes at an early stage of the differentiation program
Keywords: C/EBPα; CCAAT/enhancer-binding protein-α; FABP4/aP2; adipose specific fatty acid binding protein; FCS; foetal calf serum; GPDH; Sn-glycerol-3-phosphate dehydrogenase; HBSS; Hank's balanced salt solution; HDAC; histone deacetylase; HDACi; histone deacety
A Rationally Designed Histone Deacetylase Inhibitor with Distinct Antitumor Activity against Ovarian Cancer
Keywords: HDAC; histone deacetylase; HDACI; histone deacetylase inhibitor; SAHA; suberoylanilide hydroxamic acid; VPA; valproic acid; AE1/AE3; a mixture of two monoclonal antibodies (AE1 and AE3), with broad specificity against cytokeratins; NOSE; normal ovarian su
Histone deacetylase inhibitor SAHA induces ERα degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling
Keywords: HDACi; SAHA; ERα; Breast cancer; CHIP; Hsp90
Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and ÎFosB expression in the striatum and locomotor sensitization in mice
Keywords: histone deacetylase; cAMP responsive element binding protein; chromatin immunoprecipitation; butyric acid; valproic acid; amphetamine; AcH4; acetylated H4; BA; butyric acid; B+S; butyric acid+saline; ChIP; chromatin immunoprecipitation; co-IP; co-immunopr
Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid
Keywords: Histone deacetylase; HDAC inhibitor; HDACi; SAHA
Histone deacetylase inhibitors suppress natural killer cell cytolytic activity
Keywords: CT; threshold cycles; DNAM-1; DNAX accessory molecule-1; FCS; fetal calf serum; HDACi; histone deacetylase inhibitors; IL-2; interleukin-2; IMDM; Iscove's modified Dulbecco's medium; KIR; killer immunoglobulin-like receptors; LFA-1; lymphocyte functio
Boric acid inhibits embryonic histone deacetylases: A suggested mechanism to explain boric acid-related teratogenicity
Keywords: Borate; Axial malformations; HDAC; HDACi; Embryo; Fetus; Mechanism; Kinetic analysis
The Expanding Role of Epigenetics in the Development, Diagnosis and Treatment of Prostate Cancer and Benign Prostatic Hyperplasia
Keywords: prostate; prostatic neoplasms; genetics; DNA methylation; chromatin; 5-AC; 5-aza-cytidine; BPH; benign prostatic hyperplasia; DAC; 5-aza-deoxycytidine; EGCG; (-)-epigallocatechin-3-gallate; HAT; histone acetyltransferase; HDAC; histone deacetylase; HDACi;
A role for epigenetics in hearing: Establishment and maintenance of auditory specific gene expression patterns
Keywords: CpG; the DNA sequence “CG” where DNA methylation occurs; SINES; short interspersed transposable elements; LINES; long interspersed transposable elements; DNMT; DNA methyltransferase; siRNA; small interfering RNA; miRNA; Micro RNA; H; histone; HAT; his
The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors
Keywords: APC; adenomatous polyposis coli; CRC; colorectal carcinoma; Dkk1; Dickkopf-1; EGFP; enhanced green fluorescent protein; GSK-3beta; glycogen synthase-kinase 3beta; BCT; beta-catenin-Tcf; HDACi; histone deacetylase inhibitors; LRP; low-density lipoprotein r
Substituted N-(2-aminophenyl)-benzamides, (E)-N-(2-aminophenyl)-acrylamides and their analogues: Novel classes of histone deacetylase inhibitors
Keywords: Histone deacetylase inhibitors; 2-Aminophenyl-benzamides; 2-Aminophenyl-acrylamides; HDAC; HDACI
Recruitment of Ataxia-Telangiectasia Mutated to the p21waf1 Promoter by ZBP-89 Plays a Role in Mucosal Protection
Keywords: ATM; ataxia-telangiectasia mutated; ChIP; chromatin immunoprecipitation; DAPA; DNA affinity precipitation assay; DSS; dextran sodium sulfate; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitor; PID; p300-interacting domain; SCFA; short-chain