دانلود مقالات ISI درباره HDAC + ترجمه فارسی

فرصت های درمانی مبتنی بر مدولاسیون کاسپاز

Therapeutic opportunities based on caspase modulation

Keywords: HDAC; 5-Aza; 5-Aza-2-deoxycytidine; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; BIR; baculoviral inhibitor of apoptosis repeat; CAD; caspase-activated deoxyribonuclease; CDK; cyclin-dependent kinase; cIAP; cellular inhibitor of apoptosis; CL

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

مکانیسم محافظت مهار کننده دیاستیلاز بر طحال موش صحرایی با شوک هموراژیک شدید

Protection mechanism of deacetylase inhibitor on spleen of rats with severe hemorrhagic shock

Keywords: HDAC; Hemorrhagic shock; HDACIs; Apoptosis; Histone acetylation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

استفاده از داروهای گیاهی و محصولات طبیعی: رویکرد جایگزین برای غلبه بر مقاومت آپوپتوتیک سرطان پانکراس

Use of herbal medicines and natural products: An alternative approach to overcoming the apoptotic resistance of pancreatic cancer

Keywords: HDAC; 5-FU; 5-fluorouracil; AR; apoptotic resistance; ASK1; apoptosis signal-regulating kinase 1; BD,; bruceine D; COX-2; cyclooxygenase-2; EGCG,; epigallocatechin-3-gallate; EGFR,; epidermal growth factor receptor; EriB; eriocalyxin B; ERK,; extracellular sign

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms controlling the anti-neoplastic functions of FoxO proteins

Keywords: HDAC; ATM; ataxia telangiectasia mutated; cHL; classical hodgkin lymphoma; CML; chronic myelogenous leukemia; CSC; cancer stem cell; ERK; the extracellular signal-regulated kinase; ERα; the nuclear receptor estrogen receptor α; FoxO; forkhead box O; G6PC; glu

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Design, virtual screening, molecular docking and molecular dynamics studies of novel urushiol derivatives as potential HDAC2 selective inhibitors

Keywords: HDAC; HDAC; histone deacetylases; HDACIs; histone deacetylases inhibitors; HDLP; histone deacetylases - like protein; MDS; molecular dynamics simulation; MD; molecular dynamics; RMSD; root mean square deviations; RMSF; root mean squared fluctuation; Urushiol de

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study

Keywords: HDAC; HDACs; HDACIs; Benzamides; Anti-tumor drugs; In vivo oral activity;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Valproic acid sensitizes breast cancer cells to hydroxyurea through inhibiting RPA2 hyperphosphorylation-mediated DNA repair pathway

Keywords: HDAC; VPA; valproic acid; HU; hydroxyurea; IR; ionizing radiation; DSBs; double-strand breaks; HR; homologous recombination; RPA; replication protein A; RPA2-p; hyperphosphorylation of RPA2; wtRPA2; wild-type RPA2; muRPA2; hyperphosphorylation mutant RPA2; HDAC

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

T-cell therapies for HIV: Preclinical successes and current clinical strategies

Keywords: HDAC; adoptive T-cell therapy; artificial TCR; chimeric antigen receptors; CRISPR; gene editing; HDACIs; HIV; ZFN;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Histone H3 acetylation in the postmortem Parkinson's disease primary motor cortex

Keywords: HDAC; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; AcH3; acetylated histone H3; AcH3K9; acetylated histone H3 lysine 9; AcH3K14; acetylated histone H3 lysine 14; AcH3K18; acetylated histone H3 lysine 18; AcH3K23; acetylated his

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity

Keywords: HDAC; HDACs; HDACIs; Anti-tumor drugs; Antiproliferative activity; In vivo oral activity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Development of N-hydroxybenzamide derivatives with indole-containing cap group as histone deacetylases inhibitors

Keywords: HDAC; HDACs; HDACIs; HDAC inhibitory activity; Antiproliferative activity; Class I and class IIa cellular activity

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of a novel synergistic induction of cell death by Smac mimetic and HDAC inhibitors in acute myeloid leukemia cells

Keywords: HDAC; Apoptosis; Smac; Leukemia; Necroptosis; AML; acute myeloid leukemia; CI; combination index; cIAP; cellular inhibitor of apoptosis protein; FACS; fluorescence-activated cell-sorting analysis; FCS; fetal calf serum; FLT3; Fms-like tyrosine kinase 3; FSC/SSC

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

Class I-specific histone deacetylase inhibitor MS-275 overrides TRAIL-resistance in melanoma cells by downregulating c-FLIP

Keywords: HDAC; HDACis; Apoptosis; TRAIL; c-FLIP; Cutaneous melanoma; Uveal melanoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Bis-pyrrolyl-tetrazolyl derivatives as hybrid polar compounds: A case of lipophilic functional bioisosterism with bis-acetamides

Keywords: HDAC; Pyrrolyl-tetrazolyl derivatives; Hybrid polar compounds; Inducers of differentiation; MEL cells; HDACIs; histone deacetylase inhibitors; HMBA; hexamethylenebisacetamide; HPCs; hybrid polar compounds; HSCs; hematopoietic stem cells; LICs; leukemia initiati

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleDual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

Keywords: HDAC; mTOR; mammalian target of rapamycin; mTORC1/C2; mammalian target of rapamycin complex 1 and 2; HCC; hepatocellular carcinoma; HDACis; histone deacetylase inhibitors; mTORKis; mTOR kinase inhibitors; PCD; programmed cell death; DMSO; dimethyl sulfoxide; ca

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylase inhibitor trichostatin A enhances myogenesis by coordinating muscle regulatory factors and myogenic repressors

Keywords: HDAC; HDACIs; histone deacetylase inhibitors; TSA; Trichostatin A; MRFs; myogenic regulatory factors; DAPC; dystrophin-associated proteins complex; MHC; myosin heavy chain; Histone deacetylase inhibitors; Myogenic regulatory factors; Myogenic repressors; Dystro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه