Keywords: مسیر جاده ی جوجه تیغی; Anti-tumor drug; Hedgehog pathway; Apoptosis; Caspase8; Smoothened;
مقالات ISI مسیر جاده ی جوجه تیغی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Hedgehog inhibitors; GLI antagonists; SMO antagonists; Anticancer agents; Combination therapies;
Keywords: مسیر جاده ی جوجه تیغی; Astilbin; Anti-pulmonary fibrosis; Hedgehog pathway;
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Liver disease; Wound healing response;
Keywords: مسیر جاده ی جوجه تیغی; Breast cancer; Itraconazole; Apoptosis; Autophagic cell death; Hedgehog pathway;
Keywords: مسیر جاده ی جوجه تیغی; HIV-associated nephropathy; Podocyte; Hedgehog pathway; Epithelial-mesenchymal transition;
Keywords: مسیر جاده ی جوجه تیغی; bFGF; Hedgehog pathway; β-catenin; Fibroblast migration; Skin wound healing;
Keywords: مسیر جاده ی جوجه تیغی; Quinazolinone; Isoindolinone; Hedgehog pathway; Structure hopping; Smoothened; Gli;
Keywords: مسیر جاده ی جوجه تیغی; Basal cell carcinoma; Vulva; Lung metastasis; Hedgehog pathway; SMO inhibitors; Vismodegib;
Keywords: مسیر جاده ی جوجه تیغی; Gorlin syndrome; Nevoid basal cell carcinoma syndrome; Hedgehog pathway; Human fibroblasts;
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Smoothened; Antagonist; GPCR; Scaffold hopping; Cancer therapy
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Patched1; Estrogen receptor; Mesenchymal dysplasia; Mammary gland;
Vismodegib: revisión
Keywords: مسیر جاده ی جوجه تیغی; Vismodegib; Carcinoma basocelular; Vía HedgehogVismodegib; Basal cell carcinoma; Hedgehog pathway
Basal cell nevus syndrome (Gorlin syndrome): genetic insights, diagnostic challenges, and unmet milestones
Keywords: مسیر جاده ی جوجه تیغی; Gorlin syndrome; Chemopreventive agents; PTCH 1 mutation; Basal cell nevus syndrome; Odontogenic keratocyst; SUFU; Hedgehog pathway; Carnoy's solution; Vismodegib; Hedgehog signaling inhibitor; Basal cell carcinoma;
HDAC6 inhibition induces glioma stem cells differentiation and enhances cellular radiation sensitivity through the SHH/Gli1 signaling pathway
Keywords: مسیر جاده ی جوجه تیغی; Gloima stem cells; Radioresistance; HDAC6; Hedgehog pathway; Gli1;
Original research articleDifferential requirement of SUFU in tissue development discovered in a hypomorphic mouse model
Keywords: مسیر جاده ی جوجه تیغی; GLI; glioma associated protein; HH; hedgehog; Hypo; hypomorph; SUFU; suppressor of fused; Hedgehog pathway; Suppressor of Fused; GLI; Hypomorph; Embryogenesis; Skeletogenesis;
Possible antifibrotic effect of GDC-0449 (Vismodegib), a hedgehog-pathway inhibitor, in mice model of Schistosoma-induced liver fibrosis
Keywords: مسیر جاده ی جوجه تیغی; GDC-0449; Vismodegib; Schistosomiasis; Liver fibrosis; Hedgehog pathway;
Mono-2-ethyhexyl phthalate advancing the progression of prostate cancer through activating the hedgehog pathway in LNCaP cells
Keywords: مسیر جاده ی جوجه تیغی; Prostate cancer; Hedgehog pathway; MEHP; PTCH; LNCaP;
Vismodegib, itraconazole and sonidegib as hedgehog pathway inhibitors and their relative competencies in the treatment of basal cell carcinomas
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Basal cell carcinoma; Metastasis; Vismodegib; Sonidegib; Itraconazole;
A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancer
Keywords: مسیر جاده ی جوجه تیغی; Small cell lung cancer; LDE225; Hedgehog pathway; Hedgehog inhibitor; Circulating tumor cells; SOX2 amplification;
Non-canonical GLI1/2 activation by PI3K/AKT signaling in renal cell carcinoma: A novel potential therapeutic target
Keywords: مسیر جاده ی جوجه تیغی; Renal cell carcinoma; Hedgehog pathway; VHL; PI3K/AKT; Therapeutic target;
Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-β pathways
Keywords: مسیر جاده ی جوجه تیغی; Cancer-associated fibroblasts; Metastasis; Chemokines; Hedgehog pathway; TGF-β pathwayα-SMA, α-smooth muscle actins; CAFs, cancer-associated fibroblast; CCL2/5/7, chemokine (C-C motif) ligand 2/5/7; CXCL16, chemokine (C-X-C motif) ligand 16; CM, condition
Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways
Keywords: مسیر جاده ی جوجه تیغی; HCC; hepatocellular carcinoma; NDEA; N-nitrosodiethyl amine; CD44; cluster of differentiation 44; sFRP1; secreted frizzled-related protein 1; APC; adenomatosis polyposis coli; Hh; hedgehog pathway; Gli1; glioma-associated oncogene homolog 1; SMO; smoothen
Three new alkaloids from Veratrum grandiflorum Loes with inhibition activities on Hedgehog pathway
Keywords: مسیر جاده ی جوجه تیغی; MKTHNJPTUZGQKW-HONDGTIGSA-N; FGHYCHMFEZLWID-UMOUAYEASA-N; NLGJMOOSZNXOJW-SOIZSJQQSA-N; HVBLJFJOQGJVJC-VEGGUYCISA-N; FSMHPYDCTDZJLV-XDBXMKMXSA-N; JVKYZPBMZPJNAJ-BGLVMKAVSA-N; VZBCOPRNVQLISP-RHOBIVGRSA-N; Alkaloids; Veratrum grandiflorum Loes; Hedgehog path
Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma
Keywords: مسیر جاده ی جوجه تیغی; Basal cell carcinoma; Hedgehog pathway; PTCH1; SMO; Vismodegib; Primary resistance; Secondary resistance;
Targeting GLI factors to inhibit the Hedgehog pathway
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; GLI antagonists; drug discovery; cancer
The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth
Keywords: مسیر جاده ی جوجه تیغی; GLI1; Hedgehog pathway; Transcriptional regulation; Angiogenesis; Cancer
Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation
Keywords: مسیر جاده ی جوجه تیغی; Glioma; Hedgehog pathway; Isocitrate dehydrogenase
Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMO
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Smoothened; Patched; Amide isosteres; p38; Heterocycles
Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Vitamin D3; Vitamin D2; Gli1; Cyp24A1; Vitamin D receptor
Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Vitamin D3; Vitamin D receptor; Gli1; Cyp24A1
Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and KAAD-cyclopamine
Keywords: مسیر جاده ی جوجه تیغی; Cyclopamine; Cancer; Enzyme-linked immunoassay; Hedgehog pathway
Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma
Keywords: مسیر جاده ی جوجه تیغی; Gene copy number; Hedgehog pathway; GLI; Diffuse large B-cell lymphoma;
SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial–mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway
Keywords: مسیر جاده ی جوجه تیغی; SDF-1, stromal-derived factor-1; CXCR4, C-X-C, chemokine receptor type 4; SMO, smoothened; Gli-1, glioma-associated oncogene homolog-1; EMT, epithelial–mesenchymal transitionCXCR4; Hedgehog pathway; Pancreatic cancer invasion; Epithelial–mesenchymal trans
Systemic therapy for disseminated basal cell carcinoma: An uncommon manifestation of a common cancer
Keywords: مسیر جاده ی جوجه تیغی; Metastatic basal cell carcinoma; Chemotherapy; Targeted therapy; Hedgehog pathway; GDC-0449
Expression of hedgehog signaling molecules in lung cancer
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Lung cancer; Smoothened; Rab23; PDGFRα; Hedgehog interacting protein
N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Smoothened antagonist; Hedgehog inhibitor;
Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydroimid azo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part 1
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Smoothened antagonist; Hedgehog inhibitor
Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Smoothened antagonist; Hedgehog inhibitor
Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Smoothened antagonist; Hedgehog inhibitor;
Molecular organization of the cullin E3 ligase adaptor KCTD11
Keywords: مسیر جاده ی جوجه تیغی; Ubiquitination; Protein–protein interactions; Medulloblastoma; Hedgehog pathway; Structure–function relationships; Light scatteringKCTD, potassium channel tetramerization domain containing proteins; PDB, protein data bank; sKCTD11 and lKCTD11, short and l
Gli1 is a potential target for alleviating multidrug resistance of gliomas
Keywords: مسیر جاده ی جوجه تیغی; Chemoresistance; Glioma; Recurrence; Hedgehog pathway; Gli1
Hedgehog beyond medulloblastoma and basal cell carcinoma
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Medulloblastoma; Basal cell carcinoma; Pancreatic cancer; Mouse cancer models; Small-molecule inhibitors
Discovery of N-[(1-aryl-1H-indazol-5-yl)methyl]amides derivatives as smoothened antagonists for inhibition of the hedgehog pathway
Keywords: مسیر جاده ی جوجه تیغی; Hedgehog pathway; Smoothened antagonists; N-[(1-aryl-1H-indazol-5-yl)methyl]amide derivatives;
PTCH1 isoforms in odontogenic keratocysts
Keywords: مسیر جاده ی جوجه تیغی; Odontogenic keratocyst; PTCH tumor suppressor gene; Alternative first exons; Hedgehog pathway; Nevoid Basal Cell Carcinoma Syndrome
GDC-0449—A potent inhibitor of the hedgehog pathway
Keywords: مسیر جاده ی جوجه تیغی; GDC-0449; Hedgehog pathway; Small molecule inhibitor
Synthesis and anticancer activity studies of cyclopamine derivatives
Keywords: مسیر جاده ی جوجه تیغی; Cyclopamine; Carbohydrates; Hedgehog pathway; Bioconjugates
Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland
Keywords: مسیر جاده ی جوجه تیغی; Lef1; Mammary gland; TOPGAL; Wnt signaling; Hedgehog pathway;