دانلود مقالات ISI درباره پاکسازی کبد + ترجمه فارسی

Hepatic Metabolism and Biliary Excretion of Valerenic Acid in Isolated Perfused Rat Livers: Role of Mrp2 (Abcc2)

Keywords: پاکسازی کبد; valerenic acid; hepatic metabolism; hepatic clearance; biliary excretion; multidrug resistance-associated protein 2; HPLC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Estimation of the extent of oral absorption in animals from oral and intravenous pharmacokinetic data in drug discovery

Keywords: پاکسازی کبد; absorption; bioavailability; ADME; hepatic clearance; oral absorption; pharamcokinetics;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Optimization of an isolated perfused rainbow trout liver model: Clearance studies with 7-ethoxycoumarin

Keywords: پاکسازی کبد; Isolated perfused fish liver; Trout; 7-Ethoxycoumarin; Hepatic clearance; Metabolism

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Metabolism and Disposition of Resveratrol in the Isolated Perfused Rat Liver: Role of Mrp2 in the Biliary Excretion of Glucuronides

Keywords: پاکسازی کبد; resveratrol; hepatic metabolism; hepatic clearance; biliary excretion; multidrug resistance‐associated proteins; HPLC;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Hepatic Disposition of the Cytochrome P450 2E1 Marker Chlorzoxazone and its Hydroxylated Metabolite in Isolated Perfused Rat Livers

Keywords: پاکسازی کبد; cytochrome P450; CYP enzymes; CYP2E1; hepatic clearance; biliary clearance; hepatic metabolism; disposition; nonlinear metabolism; isolated rat liver perfusion; rats;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Effects of renal failure on drug transport and metabolism

Keywords: پاکسازی کبد; Renal failure; Uptake transporters; Efflux transporters; Hepatic clearance; Uremic toxinsAUC, area under the curve; CLint, intrinsic clearance; CMPF, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid; CRF, chronic renal failure; CYP450, cytochrome P450; E

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

An integrated approach to model hepatic drug clearance

Keywords: پاکسازی کبد; Physiologically based pharmacokinetic (PBPK) model; Zonal liver model; Hepatic clearance; Drug transport; Metabolism; Modeling and simulation

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Hepatobiliary Disposition of Liposomal Amphotericin B in the Isolated Perfused Rat Liver

Keywords: پاکسازی کبد; liposomes; hepatobiliary disposition; hepatic clearance; biliary excretion; nonlinear pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Kupffer cell ablation attenuates cyclooxygenase-2 expression after trauma and sepsis1

Keywords: پاکسازی کبد; trauma; sepsis; Kupffer cells; COX-2; prostaglandins; liver damage; hepatic clearance; femur fracture; cecal ligation and puncture;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Application of substrate depletion assay for early prediction of nonlinear pharmacokinetics in drug discovery: Assessment of nonlinearity of metoprolol, timolol, and propranolol

Keywords: پاکسازی کبد; first-pass metabolism; hepatic clearance; in vitro/in vivo correlations; nonlinear pharmacokinetics; physiological model; simulation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Influence of the physicochemical properties of liposomes on the accelerated blood clearance phenomenon in rats

Keywords: پاکسازی کبد; ABC; accelerated blood clearance; CHOL; cholesterol; 3H-CHE; 3H-cholesterylhexadecyl ether; CL; conventional liposomes; CLh; hepatic clearance; DCP; dicetylphosphate; DPPC; dipalmitoyl phsophatidylcholine; DPPG; dipalmitoyl phsophatidylglycerol; HEPC; hyd

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه