Keywords: HG، گلوکز بالا; AGEs, advanced glycation endproducts; AR, aldose reductase; ARI, aldose reductase inhibitor; BGG, beta-glucogallin; DR, diabetic retinopathy; ER, endoplasmic reticulum; ERK, extracellular signal-regulated kinase; HG, high glucose; MAPK, mitogen-activated
مقالات ISI HG، گلوکز بالا (ترجمه نشده)
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Keywords: HG، گلوکز بالا; ACh, acetylcholine; Akt, protein kinase B; AMPK, 5′ AMP-activated protein kinase; EDV, endothelium-dependent vasodilatation; eNOS, endothelial nitric oxide synthase; HG, high glucose; MMECs, mouse microvascular endothelial cells; mTOR, mammalian target fo
Histone methyltransferase Suv39h1 attenuates high glucose-induced fibronectin and p21WAF1 in mesangial cells
Keywords: HG، گلوکز بالا; Suv39h1, Suppressor of variegation 3–9 homolog 1; DN, diabetic nephropathy; H3K9me3, trimethylated lysine 9 of histone H3; HG, high glucose; HMT, histone lysine methyltransferase; PI3K, phosphoinositide 3-kinase; TGFβ, transforming growth factor-β; ERK, e
ZLN005 protects cardiomyocytes against high glucose-induced cytotoxicity by promoting SIRT1 expression and autophagy
Keywords: HG، گلوکز بالا; NF-κB, nuclear factor-κB; SIRT1, silent information regulator 2 homolog 1; HG, high glucose; FoxO, forkhead box O; NAD, nicotinamide adenine dinucleotide; PPAR, peroxisome proliferator-activated receptor; PGC-1α, peroxisome proliferator-activated receptor
GPER inhibits diabetes-mediated RhoA activation to prevent vascular endothelial dysfunction
Keywords: HG، گلوکز بالا; GPER; Diabetes mellitus; Endothelial dysfunction; Apoptosis; Oxidative stress; Inflammation; RhoA; Vascular biologyGPER, G protein-coupled estrogen receptor; OVX, ovariectomized; HG, high glucose; DM, diabetes mellitus; NO, nitric oxide; ROS, reactive oxy
Lentivirus mediated over expression of CGRP inhibited oxidative stress in Schwann cell line
Keywords: HG، گلوکز بالا; CGRP, calcitonin gene related peptide; WT, wild type; NG, normal glucose; HG, high glucose; SOD, superoxide dismutase; MDA, malondialdehyde; NOX, nicotinamide-adenine dinucleotide phosphate oxidaseCGRP; Schwann cell; Oxidative stress
Fluorine-18 Fluorodeoxyglucose Uptake in Hepatocellular Carcinoma: Correlation with Glucose Transporters and p53 Expression
Keywords: HG، گلوکز بالا; genetic profile; GLUTs; hepatocellular carcinoma; p53; [18F]FDGHCC, hepatocellular carcinoma; GLUTs, glucose transporters; PET, Positron Emission Tomography; [18F]FDG, fluorine-18 fluorodeoxyglucose; CPM, counts per minute; HG, high glucose; LG, low gluco
Resveratrol inhibits high glucose induced collagen upregulation in cardiac fibroblasts through regulating TGF-β1–Smad3 signaling pathway
Keywords: HG، گلوکز بالا; Ang II, angiotensin II; CFs, cardiac fibroblasts; ECM, extracellular matrix; HG, high glucose; RAAS, rennin-angiotensin system; Res, resveratrol; TGF-β1, transforming growth factor-β1Resveratrol (Res); Cardiac fibrosis; Angiotensin II (Ang II); Cardiac fi
Activation of FoxO1/ PGC-1α prevents mitochondrial dysfunction and ameliorates mesangial cell injury in diabetic rats
Keywords: HG، گلوکز بالا; Diabetic nephropathy; Forkhead box class O1; Peroxisome proliferator-activated receptor γ co-activator 1α; Oxidative stressDN, diabetic nephropathy; FoxO1, forkhead-box class O1; HG, high glucose; MC, mesangial cell; MDA, malondialdehyde; Mfn2, mitofusin
Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis
Keywords: HG، گلوکز بالا; 3-MA, 3-methyladenine; AMPK, adenosine monophosphate-activated protein kinase; CIMP, conditionally immortalized mouse podocyte; DN, diabetic nephropathy; HG, high glucose; HO-1, heme oxygenase-1; mTOR, mammalian target of rapamycin; NG, normal glucoseAuto
Klotho attenuates high glucose-induced fibronectin and cell hypertrophy via the ERK1/2-p38 kinase signaling pathway in renal interstitial fibroblasts
Keywords: HG، گلوکز بالا; DN, diabetic nephropathy; TGF-β, transforming growth factor-β; HG, high glucose; ERK, extracellular signal-regulated kinase; TGF-βR, TGF-β receptor; FGF23, fibroblast growth factor 23; DMEM, Dulbecco’s Modified Eagle Medium; SDS, sodium dodecyl sulfate; F
Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose
Keywords: HG، گلوکز بالا; HG, high glucose; AP, argpyrimidine; GLO-1, glyoxalase 1; MG, methylglyoxal; AGEs, advanced glycation end-products; GLO-1-MCs, GLO-1-overexpressing mesangial cells; 8-OHdG, 8-hydroxy-deoxyguanosine; 4-HNE, hydroxyl-2-nonenal; PARP-1, poly(ADP-ribose) poly
Dietary apigenin regulates high glucose and hypoxic reoxygenation-induced reductions in apelin expression in human endothelial cells
Keywords: HG، گلوکز بالا; DM, diabetes mellitus; FGFR, fibroblast growth factor receptor; FATP, fatty acid transport protein; HIF-1, hypoxia-inducible factor 1; H/R, reoxygenation after hypoxia; HG, high glucose; ROS, reactive oxygen species; TNF, tumor necrosis factor; VEGFR, vas
Activation of AMP-activated protein kinase alleviates High-glucose-induced dysfunction of brain microvascular endothelial cell tight-junction dynamics
Keywords: HG، گلوکز بالا; AMPK-CA, constitutively active AMPK mutant; AMPK-DN, dominant negative AMPK mutant; AICAR, 5-amino-4-imidazole carboxamide riboside; AMPK, AMP-activated protein kinase; GFP, green fluorescent protein; HG, high glucose; HBMEC, human brain microvascular end
High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol
Keywords: HG، گلوکز بالا; ECM, extracellular matrix; H2DCF-DA, 2′ 7′-dichlorodihydrofluorescein diacetate; HG, high glucose; MAP, mitogen-activated protein; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NAC, N-acetyl cysteine; NG, normal glucose; ROS, reactive
Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose
Keywords: HG، گلوکز بالا; DR, diabetic retinopathy; HG, high glucose; TNFR1, tumor necrosis factor receptor 1; sTNFR1, soluble tumor necrosis factor receptor 1; TNFR2, tumor necrosis factor receptor 2; TACE, tumor necrosis factor-α converting enzymeDiabetic retinopathy; Neurodegen
The protective effect of Alpha lipoic acid on Schwann cells exposed to constant or intermittent high glucose
Keywords: HG، گلوکز بالا; AIF, apoptosis inducing factor; ALA, Alpha lipoic acid; Apaf-1, apoptotic protease-activating factor-1; cyto c, cytochrome c; DPN, diabetic peripheral neuropathy; 8-OHdG, 8-hydroxy-2-deoxy Guanosine; HG, high glucose; IHG, intermitient high glucose; SDS-P
p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells
Keywords: HG، گلوکز بالا; TXNIP, thioredoxin interacting protein; TRX, Thioredoxin; HG, high glucose; MMC, mouse mesangial cell; DN, diabetic nephropathy; MAPK, mitogen-activated protein kinase; ROS, reactive oxygen speciesHigh glucose; Thioredoxin interacting protein; p38 mitogen
Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts
Keywords: HG، گلوکز بالا; α-SMA, α-smooth muscle actin; DN, diabetic nephropathy; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; HG, high glucose; HM, high mannitol; JAK2, Janus kinase 2; JNK, c-Jun N-terminal kinase; LDH, lactate dehydrogenase; MAPK, mitog
HGF suppresses high glucose-mediated oxidative stress in mesangial cells by activation of PKG and inhibition of PKA
Keywords: HG، گلوکز بالا; HGF, hepatocyte growth factor; HG, high glucose; NG, normal glucose; ROS, reactive oxygen species; GCLC, glutamate-cysteine ligase catalytic subunit; G6PD, glucose-6-phosphate dehydrogenase; USF, upstream stimulatory factor; PKA, cAMP-dependent protein ki
Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy
Keywords: HG، گلوکز بالا; cannabinoids; diabetic complications; inflammation; oxidative stressADP, adenosine diphosphate; CBD, cannabidiol; HCM, human cardiomyocytes; HG, high glucose; HNE, hydroxynonenal; ICAM, intercellular adhesion molecule; IκB-α, inhibitor of nuclear transcri
Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis
Keywords: HG، گلوکز بالا; HG, high glucose; HM, high mannitol; NF-κB, nuclear factor-κB; IκBα, inhibitor κBα; HUVECs, human umbilical vein endothelial cells; COX, cyclooxygenase; PGE2, prostaglandin E2; ROS, reactive oxygen species; EMSA, electrophoretic mobility shift assay; DCFH
Oxidative stress contributes to accelerated development of the senescent phenotype in human peritoneal mesothelial cells exposed to high glucose
Keywords: HG، گلوکز بالا; GPx, glutathione peroxidase; H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate; HG, high glucose; HPMC, human peritoneal mesothelial cells; NG, normal glucose; 8-OH-dG, 8-hydroxy-2′-deoxyguanosine; OTZ, L-2-oxothiazolidine-4-carboxylic acid; PDF, perito
The Pathogenesis of Myocardial Fibrosis in the Setting of Diabetic Cardiomyopathy
Keywords: HG، گلوکز بالا; AGE, advanced glycosylation end products; Ang II, angiotensin II; DAG, diacylglycerol; DM, diabetes mellitus; DN, diabetic nephropathy; ECM, extracellular matrix; HG, high glucose; LV, left ventricle/ventricular; MMP, matrix metalloproteinases; PKC, prote