Keywords: آمار به رهبری; Antibiotic discovery; High-throughput screening; Hit to lead; Dose response;
مقالات ISI آمار به رهبری (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Lead identification of novel and selective TYK2 inhibitors
Keywords: آمار به رهبری; Kinase inhibitor; Janus family kinase; Structure–activity relationship; Crystal structure; Hit to lead; Immunology
Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist
Keywords: آمار به رهبری; Obesity; NPY Y5 receptor antagonist; GPCR; Benzoxazole; Hit to lead;
4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators
Keywords: آمار به رهبری; mGlu4 PAM; Positive allosteric modulation; Parkinson's disease; Structure-activity relationships; Hit to lead;
Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors
Keywords: آمار به رهبری; PDE10A; Phosphodiesterase; Hit to lead; Enzyme inhibitor; Naphthyridine;
Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors
Keywords: آمار به رهبری; PIM inhibitors; Scaffold hopping; Triazolopyridine; Hit to lead; Phosphorylation of BAD; FLT-3; Crystal structure; Docking; hERG Binding; Mechanism of action
Hit to Lead optimization of a novel class of squarate-containing polo-like kinases inhibitors
Keywords: آمار به رهبری; Plk; Kinases; Antitumor; Hit to Lead;
3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts
Keywords: آمار به رهبری; mGluR2; Metabotropic glutamate receptors; Positive allosteric modulator; Schizophrenia; Oxazolidinone; Hit to lead
Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR)
Keywords: آمار به رهبری; Solid-phase library; Hit to lead; Combinatorial chemistry; Non-additive SAR; Non-linear SAR; Growth hormone secretagogue receptor; GHSR; G-protein coupled receptor; GPCR; Solid-phase synthesis; Parallel synthesis; GPCR agonist; Matrix library
Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists
Keywords: آمار به رهبری; mGluR1 antagonist; Hit to lead; ADME
Discovery of potent and selective PKC-θ inhibitors
Keywords: آمار به رهبری; PKC-θ; Kinase; Inhibitor; Hit to lead