دانلود مقالات ISI درباره HU، هیدروکسی اوره + ترجمه فارسی

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Preventing replication fork collapse to maintain genome integrity

Keywords: HU، هیدروکسی اوره; Fork collapse; Replication checkpoint; ATR; Replisome; iPONDATR, ATM and Rad3-related; RPA, Replication protein A; iPOND, Isolation of proteins on nascent DNA; ChIP, Chromatin immunoprecipitation; HU, Hydroxyurea; ssDNA, Single-stranded DNA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

YPL260W, a high-copy suppressor of a copper-sensitive phenotype in yeast, is linked to DNA repair and proteasome function

Keywords: HU، هیدروکسی اوره; BCA, bicinchoninic acid; CP, core particle; DNase I, deoxyribonuclease I; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HRP, horseradish peroxidase; HU, hydroxyurea; ICAR, immobilized cobalt affinity resin; kDa, kilodalton(s); MDa, megadalton

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Hydroxyurea-induced replication stress causes poly(ADP-ribose) polymerase-2 accumulation and changes its intranuclear location in root meristems of Vicia faba

Keywords: HU، هیدروکسی اوره; DDR, DNA Damage Response; dNTP, deoxyribonucleoside triphosphates; DSBs, double-Strand Breaks; TEM, transmission electron microscopy; HU, hydroxyurea; NAD+, nicotinamide adenine dinucleotide; NE, nuclear envelope; NER, nucleotide excision repair; pADPRT,

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

XmnI polymorphism: Relation to β-thalassemia phenotype and genotype in Egyptian Children

Keywords: HU، هیدروکسی اوره; Hu, hydroxyurea; TI, thalassemia intermedia; TM, thalassemia major; CBC, complete blood count; HPLC, high performance liquid chromatography; RDB, reverse dot blot hybridizationβ-Thalassemia; XmnI polymorphism; Phenotype; Hydroxyurea; Egypt

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

The effects of hydroxyurea and bone marrow transplant on Anti-Müllerian hormone (AMH) levels in females with sickle cell anemia

Keywords: HU، هیدروکسی اوره; AMH, Anti-Müllerian hormone; BMT, bone marrow transplant; DOR, diminished ovarian reserve; HU, hydroxyurea; POI, premature ovarian insufficiency; SCA-BMT, sickle cell anemia bone marrow transplant; SCA-HU, sickle cell anemia hydroxyurea; SCA-SC, sickle ce

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

DNA repair defects ascribed to pby1 are caused by disruption of Holliday junction resolvase Mus81-Mms4

Keywords: HU، هیدروکسی اوره; YKO, yeast knockout; P body, cytoplasmic processing body; SSL, synthetic sick/syntheticlethal; SGD, Saccharomyces genome database; MMS, methyl methanesulfonate; HU, hydroxyurea; CPT, camptothecin; DRYGIN, data repository of yeast genetic interactionsSacch

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Proteasome activity is important for replication recovery, CHK1 phosphorylation and prevention of G2 arrest after low-dose formaldehyde

Keywords: HU، هیدروکسی اوره; DPC, DNA–protein crosslinks; EdU, 5-ethynyl-2′-deoxyuridine; FACS, fluorescence-activated cell sorting; FA, formaldehyde; HU, hydroxyurea; NER, nucleotide excision repair; ss, single-strandedFormaldehyde; DNA–protein crosslink; DNA repair; Replication; Ce

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Evidence for reciliation of RPE1 cells in late G1 phase, and ciliary localisation of cyclin B1

Keywords: HU، هیدروکسی اوره; Primary cilia; Cyclin B1; CDK1; Aurora A; DNA replication; Cilium disassemblyAurA, Aurora kinase A; BrdU, bromodeoxyuridine; CDK, cyclin-dependent kinase; DAPI, 4’,6-diamidino-2-phenylindole; FBS, fetal bovine serum; HU, hydroxyurea; Mim, mimosine; siRNA,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents

Keywords: HU، هیدروکسی اوره; DDK, Dbf4-dependent kinase; DDR, DNA damage response; OSCC, oral squamous cell carcinoma; IHC, immunohistochemistry; HU, hydroxyurea; CPT, camptothecin; CI, confidence interval; HR, hazard ratios; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

B cell memory following infection and challenge of channel catfish with Ichthyophthirius multifiliis

Keywords: HU، هیدروکسی اوره; HU, hydroxyurea; Ich, Ichthyophthirius multifiliis; i-antigens, immobilization-antigens; IHNV, infectious hematopoietic necrosis virus; MALT, mucosa-associated lymphoid tissues; TNP-KLH, trinitrophenylated-keyhole limpet hemocyanin; ASC, antibody secretin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level

Keywords: HU، هیدروکسی اوره; uORF, upstream open reading frame; MMS, methyl methane sulfonate; HU, hydroxyurea; αF, alpha factor; WT, wild-type; CAN, canavanine; 5-FOA, 5-fluoro-orotic acid; MCB, MluI cell cycle box; SCB, Swi6/4 cell cycle box; CCB, cell-cycle boxMismatch repair; Cel

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

RNA interference regulates the cell cycle checkpoint through the RNA export factor, Ptr1, in fission yeast

Keywords: HU، هیدروکسی اوره; RNAi, RNA interference; HU, hydroxyurea; siRNAs, small interfering RNAs; ARC, Argonaute siRNA chaperone; RDRC, RNA-directed RNA polymerase complex; RITS, RNA-induced transcriptional silencing complex; Cen, centromeric-noncoding; HP1, heterochromatin prote

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18–RFC complex and Mrc1

Keywords: HU، هیدروکسی اوره; HU, hydroxyurea; ChIP, chromatin immunoprecipitation; WT, wild typeRmi1; Sgs1; Top3; Ctf18; Mrc1; Sister chromatid cohesion

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Saccharomyces cerevisiae Tel2 plays roles in TORC signaling and telomere maintenance that can be mutationally separated

Keywords: HU، هیدروکسی اوره; ASTRA, assembly of Tel, Rvb and Atm-like kinases; ATM, ataxia telangiectasia mutated; ATR, ATM and Rad3 related; FOA, 5-fluoroorotic acid; HU, hydroxyurea; MMS, methyl methanesulfonate; PIKK, phosphatidylinositol 3-kinase-like protein kinase; TORC, target

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Drosophila Claspin is required for the G2 arrest that is induced by DNA replication stress but not by DNA double-strand breaks

Keywords: HU، هیدروکسی اوره; HU, hydroxyurea; IR, ionizing radiation; DSBs, DNA double-strand breaksDrosophila; Claspin; Replication checkpoint; Hydroxyurea; Ionizing radiation; G2 arrest

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Relationship between oxidative stress, glutathione S-transferase polymorphisms and hydroxyurea treatment in sickle cell anemia

Keywords: HU، هیدروکسی اوره; CAT, catalase; GSH, glutathione; GST, glutathione-S-transferase; HU, hydroxyurea; HPLC, high performance liquid chromatography; RBC, red blood cells; ROS, reactive oxygen species; SCA, sickle cell anemia; TBARS, thiobarbituric-acid-reacting substances; TE

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling

Keywords: HU، هیدروکسی اوره; PTEN; Resveratrol; Breast cancer; Cowden syndromeDMSO, dimethyl sulphoxide; HU, hydroxyurea; MAPK, mitogen-activated protein kinase; mTOR, mammalian target of rapamycin; mTORC1, mammalian target of rapamycin complex-1; mTORC2, mammalian target of rapamyci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination

Keywords: HU، هیدروکسی اوره; BER, base excision repair; ChIP, chromatin immunoprecipitation; CPT, camptothecin; D loop, displacement loop; DSB, double strand break; FPC, fork protection complex; HR, homologous recombination; HU, hydroxyurea; IR, ionizing radiation; MMS, methyl methan

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Spirulina maxima and its protein extract protect against hydroxyurea-teratogenic insult in mice

Keywords: HU، هیدروکسی اوره; HU, hydroxyurea; MDA, malondialdehyde; CP, C-phycocyanin; ROS, reactive oxygen species; SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis; PBS, phosphate buffer solution; RNR, ribonucleotide reductase; SP, Spirulina; SPE, Spirulina maxim

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Hydroxyurea-induced synchronisation of bloodstream stage Trypanosoma brucei

Keywords: HU، هیدروکسی اوره; HU, hydroxyurea; T. brucei, Trypanosoma brucei; N, nucleus; K, kinetoplast; DNA, deoxyribonucleic acid; dNTP, deoxyribonucleotide triphosphate; DAPI, 4,6-diamidino-2-phenylindole; PBS, phosphate buffered salineTrypanosoma brucei; Hydroxyurea; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells

Keywords: HU، هیدروکسی اوره; ATM, ataxia telangectasia mutated; ATR, AT mutated and Rad3 related; HU, hydroxyurea; ATRIP, ATR interacting proteinATR; Cdc6; Hydroxyurea; Checkpoint; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation

Keywords: HU، هیدروکسی اوره; ATM, ataxia-telangiectasia mutated; ATR, ATM- and Rad3-related; Cdk, cyclin-dependent kinase; HU, hydroxyurea; UV, ultraviolet; AS, asynchronous; GST, glutathione S-transferase; WT, Chk1 wild type; S286A, Chk1 mutated at Ser286 to Ala; S301A, Chk1 mutated

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

GSK-3β-dependent destabilization of cyclin D1 mediates replicational stress-induced arrest of cell cycle

Keywords: HU، هیدروکسی اوره; ATR, ataxia telangiectasia mutated and Rad3-related kinase; CA, constitutively active; FACS, fluorescence activated cell sorting; GSK-3β, glycogen synthase kinase-3β; GST, glutathione S-transferase; HA, hemagglutinin; HU, hydroxyurea; IP, immunoprecipitat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Cutaneous antibody-secreting cells and B cells in a teleost fish

Keywords: HU، هیدروکسی اوره; Ab, antibody; ASC, antibody-secreting cell; HU, hydroxyurea; IC, intracoelomic; i-antigen, immobilization-antigenTeleost; Antibody-secreting cell; B cell; Plasma cell; Cutaneous mucosal antibody; Skin; ELISPOT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

The role of the Saccharomyces cerevisiae Cdc7–Dbf4 complex in the replication checkpoint

Keywords: HU، هیدروکسی اوره; HU, hydroxyurea; MMS, methyl methanesulfonateCell, cycle; DNA, replication; Rad53; Dun1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Functional analysis of Drosophila melanogaster BRCA2 in DNA repair

Keywords: HU، هیدروکسی اوره; HR, homologous recombination; IR, ionising radiation; Gy, gray; DSBR, double-strand break repair; NHEJ, non-homologous end joining; dsRNA, double-stranded RNA; KD, knock-down; HU, hydroxyurea; MMS, methyl methanesulfonateBRCA2; DNA repair; DNA damage; Gen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

The genetic consequences of ablating helicase activity and the Top3 interaction domain of Sgs1

Keywords: HU، هیدروکسی اوره; MMS, methyl methanesulfonate; HU, hydroxyurea; HR, homologous recombination; HJ, Holliday junction; dHJ, double Holliday junctionSgs1; Top3; Helicase; Topoisomerase; Recombination; Saccharomyces cerevisiae

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Visualization of ribonucleotide reductase catalytic oxidation establishes thioredoxins as its major reductants in yeast

Keywords: HU، هیدروکسی اوره; RNR, class Ia ribonucleotide reductase; β-ME, β-mercaptoethanol; HU, hydroxyurea; PCR, polymerase chain reaction; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresisRibonucleotide reductase; Thioredoxin; Glutaredoxin; DNA replication; Yeas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

RPA Mediates Recombination Repair During Replication Stress and Is Displaced from DNA by Checkpoint Signalling in Human Cells

Keywords: HU، هیدروکسی اوره; Chk1, checkpoint kinase 1; DSBs, DNA double-strand breaks; HU, hydroxyurea; MRN, MRE11/RAD50/NBS1; RPA, replication protein A; siRNA, small interfering RNA; TopBP1, topoisomerase IIβ binding protein 1RPA; homologous recombination; Chk1; mammalian cells; s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

The role of β93 Cys in the inhibition of Hb S fiber formation

Keywords: HU، هیدروکسی اوره; SCD; Sickle Cell Disease; Hb; Hemoglobin; NO; Nitric Oxide; SNO-Hb; S-nitrosohemoglobin; HbNO; nitrosylhemoglobin; HbCO; carbonmonoxyhemoglobin; HU, hydroxyurea; NEM; N-ethylmaleimide; UVRR; UV resonance Raman; FT-IR; Fourier transform infrared; ESI-MS; e

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Effects on erythroid differentiation of platinum(II) complexes of synthetic bile acid derivatives

Keywords: HU، هیدروکسی اوره; Hb, hemoglobin; HbF, fetal hemoglobin; EPO, erythropoietin; FBS, fetal bovine serum; BSA, bovine serum albumin; HPLC, high-performance liquid chromatography; GAPDH, glyceraldehyde phosphate dehydrogenase; Ara-C, cytosine arabinoside; HU, hydroxyurea; RT,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

blm3-1 Is an Allele of UBP3, a Ubiquitin Protease that Appears to Act During Transcription of Damaged DNA

Keywords: HU، هیدروکسی اوره; MMS, methylmethane sulfonate; ORF, open reading frame; HU, hydroxyurea; 6-AU, 6-azauracilBlm3; Blm10/PA200; Ubp3; transcription; bleomycin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Cyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrest

Keywords: HU، هیدروکسی اوره; DC, daughter centriole; ECL, enhanced chemiluminescence; FITC, fluorescein isothiocyanate; GFP, green fluorescent protein; GST, glutathione S-transferase; HRP, horseradish peroxidase; HU, hydroxyurea; LRSC, lissamine rhodamine sulfonyl chloride; MT, micro

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2006 سفارش ترجمه