Characterization and IL-15 dependence of NK cells in humanized mice
Keywords: موش های انسانی; NK cells; NCRs; IL-15; Humanized mice
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Superior human leukocyte reconstitution and susceptibility to vaginal HIV transmission in humanized NOD-scid IL-2Rγ−/− (NSG) BLT mice
Keywords: موش های انسانی; HIV/AIDS pathogenesis; HIV vaginal transmission; Humanized mice; HIV animal models; Hematopoietic stem cells; BLT mice; NOD-scid mice; NOD-scid IL-2Rγ−/− mice
Modèles précliniques en oncologie
Keywords: موش های انسانی; cancérologie expérimentale; modèle tumoral; xénogreffes tumorales; tumeurs humaines; tumeurs murines; souris transgéniques; souris humanisées; rat immunodéprimé; experimental therapeutics; human tumor xenograft; murine tumors; transgenic mice; hum
Efficient peripheral construction of functional human regulatory CD4+CD25highFoxp3+ T cells in NOD/SCID mice grafted with fetal human thymus/liver tissues and CD34+ cells
Keywords: موش های انسانی; CPM; counts per minute; CTLA-4; cytotoxic T lymphocyte-associated antigen 4; DCs; dendritic cells; FCM; flow cytometry; FITC; fluorescein isothiocyanate; Foxp3; Forkhead box P3; GVHD; graft versus host disease; HSCs; hematopoietic stem cells; LNs; lymph n
In vitro evolution and analysis of HIV-1 LTR-specific recombinases
Keywords: موش های انسانی; In vitro evolution; Recombinase; Human immunodeficiency virus type 1; Long terminal repeat; Humanized MICE; Rag2−/−γc−/−
Dynamics of memory and naïve CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rγnull mice infected with CCR5-tropic HIV-1
Keywords: موش های انسانی; HIV-1; Humanized mice; Immunopathogenesis
Th1 and Th17 immunocompetence in humanized NOD/SCID/IL2rγnull mice
Keywords: موش های انسانی; Humanized mice; T-cell response; Delayed type hypersensitivity; Trans vivo delayed type hypersensitivity; Th1 and Th17 response
Parameters for establishing humanized mouse models to study human immunity: Analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rγnull mutation
Keywords: موش های انسانی; Humanized mice; SCID; Hematopoietic stem cells; IL-2R “common” gamma chain;
PPARα: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators
Keywords: موش های انسانی; PPAR; Peroxisome proliferators; Humanized mice; Nuclear receptors; microRNA; Wy-14,643; Fenofibrate; Hepatocellular proliferation
Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2−/−γc−/− (RAG-hu) mice
Keywords: موش های انسانی; HIV/AIDS pathogenesis; HIV vaginal and rectal transmission; Microbicides; Humanized mice; HIV-1 mucosal transmission/infection; Animal disease models; Hematopoietic stem cells; SCID-hu mice; Rag2−/−γc−/− mice; RAG-hu mice
Renal L-type fatty acid-binding protein mediates the bezafibrate reduction of cisplatin-induced acute kidney injury
Keywords: موش های انسانی; acute renal failure; fibrate; PPAR-α; apoptosis; lipotoxicity; biomarker; humanized mice
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene
Keywords: موش های انسانی; NOD-scid; IL-2r gamma chain; Humanized mice; SCID; Transplantation; Islet; Rejection; Hu-PBL-SCID; Human; Mouse
Dengue virus infection and immune response in humanized RAG2−/−γc−/− (RAG-hu) mice
Keywords: موش های انسانی; Dengue pathogenesis; Humanized mice; Dengue animal model; Dengue immunity; Rag-hu mice; Humice; Dengue viral infection; Dengue antibody dependent enhancement; Dengue neutralization; Dengue hemorrhagic fever
Human adenosine A3 receptor leads to intracellular Ca2+ mobilization but is insufficient to activate the signaling pathway via phosphoinositide 3-kinase γ in mice
Keywords: موش های انسانی; A3AR; adenosine A3 receptor; A3ARh/h mice; A3AR-humanized mice; BMMCs; bone marrow-derived mast cells; [Ca2+]i; intracellular Ca2+ concentration; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)adenosine-5â²-N-methyluronamide; DT-A; diphtheria toxin A fragment; EP