Keywords: منطقه hypervariable; Hypervariable region; Infectious bronchitis virus; Infectious clone; Recombinant IBV; Reverse genetic vaccine;
مقالات ISI منطقه hypervariable (ترجمه نشده)
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Keywords: منطقه hypervariable; Mycobacterium tuberculosis; Multidrug resistant; Rifampicin monoresistant; Hypervariable region; Isoniazid monoresistant;
Keywords: منطقه hypervariable; AKT; protein kinase B; ATF4; activating transcription factor 4; cAMP; cyclic adenosine monophosphate; CCL5; (C-C motif) ligand 5; CNS; central nervous system; 4EBP1; 4E (elF4E) binding protein; ECM; extracellular matrix; ERK; p44/p42 extracellular signal-
Keywords: منطقه hypervariable; Ad vector; Hypervariable region; Epitope display; Immune response
Retargeted and detargeted adenovirus for gene delivery to the muscle
Keywords: منطقه hypervariable; Adenovirus; Phage peptide libraries; Targeting; Detargeting; Hypervariable region; Hexon;
Tropism and transduction of oncolytic adenovirus 5 vectors in cancer therapy: Focus on fiber chimerism and mosaicism, hexon and pIX
Keywords: منطقه hypervariable; Ad; adenovirus; CAR; coxsackievirus and adenovirus receptor; DSG2; desmoglein 2; FX; blood coagulation factor X; HSG; heparan sulfate glycosaminoglycan; HVR; hypervariable region; JAM1; junction adhesion molecule 1; pK7; the polylysine peptide; pIX; prote
Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
Keywords: منطقه hypervariable; Ubiquitin-like domain; Papain-like protease; Macrodomain; Nucleic-acid binding domain; Innate immunity; Structural biology; 3CLpro; 3C-like protease; 3Ecto; Nsp3 ectodomain; ADPr; ADP-ribose; ADRP; ADP-ribose-1â³-phosphate phosphatase; ARTD; ADP-ribosylt
Research paperAccurate quantitation for in vitro refolding of single domain antibody fragments expressed as inclusion bodies by referring the concomitant expression of a soluble form in the periplasms of Escherichia coli
Keywords: منطقه hypervariable; CD; Circular Dichroism; ELISA; enzyme-linked immunosorbent assay; TCDR; three-step cold dialysis refolding; OHDR; one-step hot dialysis refolding; OCDR; one-step cold dialysis refolding; CDR; complementarity determining region; HV; hypervariable region; C
Membrane localization and dynamics of geranylgeranylated Rab5 hypervariable region
Keywords: منطقه hypervariable; Small GTPase; Peripheral membrane protein; Molecular dynamics; Hypervariable region; Lipid enrichment; Lipid-protein interactions;
Interaction of KRas4b with anionic membranes: A special role for PIP2
Keywords: منطقه hypervariable; KRas4b; Nanodisc; Cancer signaling; Lipid specificity; PIP2; CD; Catalytic Domain; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DMPS; 1,2-dimyristoyl-sn-glycero-3-phospho-l-serine; GAP; GTPase activating proteins; GDP; Guanosine diphosphate; GEF; Gu
Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection
Keywords: منطقه hypervariable; T/F; Transmitted founder; HCV; Hepatitis C virus; NS5B; Non-structural protein 5B; BNAbs; Broadly neutralizing antibodies; AR; Antigenic region; HVR; Hypervariable region; Broadly neutralizing antibodies; Hepatitis C; Epitopes; Glycoprotein E2; InC3 colla
The development and optimisation of nanobody based electrochemical immunosensors for IgG
Keywords: منطقه hypervariable; NABP; non antibody binding protein; VHH; hypervariable region; ScFv; single chain variable fragments; IgNAR; immunoglobulin new antigen receptor; Nanobody; Impedance; Immunosensor; Orientation; Spacer; Steric hindrance;
Research ArticleHepatitis E virus mutations associated with ribavirin treatment failure result in altered viral fitness and ribavirin sensitivity
Keywords: منطقه hypervariable; HEV; hepatitis E virus; RBV; ribavirin; ALT; alanine aminotransferase; IU; international units; γGT; γ-glutamyltransferase; CLL; chronic lymphoid leukemia; NGS; next-generation sequencing; RdRp; RNA-dependent RNA polymerase; HVR; hypervariable region; O
Antibodies against HLA-DP recognize broadly expressed epitopes
Keywords: منطقه hypervariable; CDC; complement-dependent cytotoxicity; DSA; donor specific antibodies; HVR; hypervariable region; MFI; mean fluorescence intensity; SRPs; selective reactivity patterns; SABs; single antigen beads; HLA; HLA-DP antibodies; Epitopes; Transplant;
Hepatitis E Virus Mutations: Functional and Clinical Relevance
Keywords: منطقه hypervariable; HEV; hepatitis E virus; ORF; open reading frame; MeT; methyltransferase; Y; Y-domain; PCP; papain-like cysteine protease; HVR; hypervariable region; X-domain; macro-domain; Hel; RNA helicase; RdRp; RNA-dependent RNA polymerase; PPR; polyproline region; CP
Analysis of new isolates reveals new genome organization and a hypervariable region in infectious myonecrosis virus (IMNV)
Keywords: منطقه hypervariable; IMNV Brazil; Hypervariable region; dsRNA virus; Shrimp diseases; IRES
Frontiers in Liver TransplantationThe impact of hepatitis E in the liver transplant setting
Keywords: منطقه hypervariable; HEV; hepatitis E virus; HVR; hypervariable region; ORF; open-reading frame; GBS; Guillain-Barrè syndrome; Hepatitis E; HEV; Liver transplantation; Treatment;
Evolutionary dynamics of the E1-E2 viral populations during combination therapy in non-responder patients chronically infected with hepatitis C virus subtype 1b
Keywords: منطقه hypervariable; Tf; final time point; HCV; hepatitis C virus; HVR; hypervariable region; Ti; initial time point; Ï; nucleotide diversity corrected by the Jukes-Cantor method; nHap; number of haplotypes; Ka; number of nonsynonymous substitutions per nonsynonymous site;
Porcine reproductive and respiratory syndrome virus diversity of Eastern Canada swine herds in a large sequence dataset reveals two hypervariable regions under positive selection
Keywords: منطقه hypervariable; Porcine reproductive and respiratory syndrome virus (PRRSV); Evolution; ORF5; GP5; Positive selection; Hypervariable region;
Ras inhibition via direct Ras binding-is there a path forward?
Keywords: منطقه hypervariable; ATP; adenosine triphosphate; FTase; farnesyltransferase; FTmap; fourier transform correlation mapping; GAP; GTPase activating protein; GDP; guanosine diphosphate; GEF; guanine-nucleotide exchange factor; GST; glutathione s-transferase; GTP; guanosine trip
Mutations That Alter Use of Hepatitis C Virus Cell Entry Factors Mediate Escape From Neutralizing Antibodies
Keywords: منطقه hypervariable; Virology; Liver Disease; Tissue Culture Model; Immunity; CLDN; claudin; HCV; hepatitis C virus; HCVcc; cell culture-derived HC; HCVpp; hepatitis C virus pseudoparticles; HMAb; human monoclonal antibody; HVR; hypervariable region; LT; liver transplantation
Human adenoviruses in respiratory infections: Sequencing of the hexon hypervariable region reveals high sequence variability
Keywords: منطقه hypervariable; hAdV, human adenovirus; HVR, hypervariable region; ORF, open reading frame; PCR, polymerase chain reactionAdenovirus; Hexon genotype; Hypervariable region; PCR
Genotypic diversity of merozoite surface antigen 1 of Babesia bovis within an endemic population
Keywords: منطقه hypervariable; MSA; merozoite surface antigen; RAP; rhoptry-associated protein; VMSA; variable merozoite surface antigen; HVR; hypervariable region; VESA; variant erythrocyte surface antigen; Babesia bovis; Merozoite surface antigen-1; Population genetics;
Expression, purification, and characterization of soluble K-Ras4B for structural analysis
Keywords: منطقه hypervariable; K-Ras4B; NMR; SPR; Hypervariable region; Nanodiscs
Unequal distribution of RT-PCR artifacts along the E1–E2 region of Hepatitis C virus
Keywords: منطقه hypervariable; RNA virus; Variability; Molecular cloning; Sequencing; Mutational hotspot; Hypervariable region
Molecular basis for the substrate specificity of plant guanine nucleotide exchange factors for ROP
Keywords: منطقه hypervariable; At; Arabidopsis thaliana; Cdc42; cell division cycle 42; cDNA; complementary DNA; Dbl; diffuse B-cell lymphoma; DH; Dbl homology; G protein; guanine nucleotide binding protein; GDI; guanine nucleotide dissociation inhibitor; GEF; guanine nucleotide exchan
Haplotype diversity in human mitochondrial DNA hypervariable regions I–III in the city of Caracas (Venezuela)
Keywords: منطقه hypervariable; Mitochondrial DNA; Database; Hypervariable region; Venezuela
Restricted quasispecies variation following infection with the GB virus B
Keywords: منطقه hypervariable; GB virus B; Envelope 2; Hypervariable region; Sequence variability; Hepatitis
Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus
Keywords: منطقه hypervariable; Positive selection; E1–E2 region; HCV; Hypervariable region; Antiviral treatment; Non-responder patient
Downregulation of Bamboo mosaic virus replication requires the 5′ apical hairpin stem loop structure and sequence of satellite RNA
Keywords: منطقه hypervariable; Hypervariable region; Satellite RNA-mediated interference of virus replication
A Deletion Variant Study of the Functional Role of the Salmonella Flagellin Hypervariable Domain Region in Motility
Keywords: منطقه hypervariable; Amp, ampicillin; LB, Luria-Bertani broth; TEM, transmission electron microscopySalmonella typhimurium; flagellin; motility; hypervariable region; optical trapping
Clinical and Therapeutic Implications of Hepatitis C Virus Compartmentalization
Keywords: منطقه hypervariable; BMC; blood mononuclear cells; HVR; hypervariable region; IRES; internal ribosomal entry site; PCR; polymerase chain reaction; SSCP; single-strand conformational polymorphism; SVR; sustained virologic response; UTR; untranslated region;
Productive Replication of Hepatitis C Virus in Perihepatic Lymph Nodes In Vivo: Implications of HCV Lymphotropism
Keywords: منطقه hypervariable; E1; envelope 1; HVR; hypervariable region; ICC; immunocytochemistry; ISH; in situ hybridization; NS3; HCV nonstructural region 3; RI; replicative intermediate;
Characterization of a highly virulent feline calicivirus and attenuation of this virus
Keywords: منطقه hypervariable; Positive-strand RNA virus; FCV; Calicivirus; Full-length capsid sequence; RT-PCR; Hypervariable region; Antigenic diversity; Serum-virus neutralization; Immunofluoresence; ELISA
Distinctly different msp2 pseudogene repertoires in Anaplasma marginale strains that are capable of superinfection
Keywords: منطقه hypervariable; msp2; major surface protein 2; opag; operon-associated gene; PCR; polymerase chain reaction; VRR; variable repeat region; HVR; hypervariable region; ES; expression site; gDNA; genomic DNA; Major surface protein; msp1α; Outer membrane protein;
Human astrovirus C-terminal nsP1a protein is involved in RNA replication
Keywords: منطقه hypervariable; Astrovirus; Replication; Hypervariable region; Nonstructural proteins; Genotypes;
Genomic organization of the sheep TRG1@ locus and comparative analyses of Bovidae and human variable genes
Keywords: منطقه hypervariable; PB; bootstrap probability; CDR; complementarity determining regions; C; constant; D; diversity; HV; hypervariable region; J; joining; LP; leader region; MHC; major histocompatibility complex; MP; maximum parsimony method; NJ; neighbor-joining method; NMD;