Pathogenesis associated with a restrictive cardiomyopathy mutant in cardiac troponin T is due to reduced protein stability and greatly increased myofilament Ca2+ sensitivity
Keywords: cTnT; cardiac Troponin T; RCM; restrictive cardiomyopathy; PKA; protein kinase A; cTnT-ÎE96; cardiac troponin T with glutamic acid 96 deleted; cTnI-SS/DD; cardiac troponin I with serines 23 and 24 mutated to aspartic acid; IAANS; 2-(4â²-(Iodoacetomido)a