Keywords: Necroptosis; Smac mimetic; Cell death; Pancreatic carcinoma; IAP proteins; cIAP; cellular IAP; FADD; Fas-associated protein with death domain; FCS; fetal calf serum; GAPDH; anti-glyceraldehyde 3-phosphate dehydrogenase; IAP; inhibitor of apoptosis; MLKL;