دانلود مقالات ISI درباره Ical + ترجمه فارسی

هیدروکسی کلروکین موجب کاهش ضربان قلب توسط تعدیل جریان جبرانی شده با هیپرپلاریزاسیون میشود: بینش الکتروفیزیولوژیک و پتانسیل درمانی

Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential

Keywords: ANOVA; analysis of variance; AP; action potential; HCQ; hydroxychloroquine; HR; heart rate; ICaL; L-type calcium ion current; If; funny current; IKr; rapid delayed rectifier potassium current; LV; left ventricle; PSS; physiological saline solution; SAN; s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

مکانیزم سلولی از کاردیومیوپاتی ناشی از انقباض بطنی زودرس

Cellular mechanism of premature ventricular contraction-induced cardiomyopathy

Keywords: AP; action potential; APD; action potential duration; [Ca2+]i; intracellular Ca2+ concentrations; CM; cardiomyopathy; CON; control; E-C; excitation-contraction; ICaL; L-type Ca current; IK1; inward rectifier current; IKr; rapid delayed rectifier current;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

مقاله اصلی در دسترس بودن داده های غربالگری کانال یون بالا و پیامدهای آن برای ارزیابی ایمنی قلب

Original articleVariability in high-throughput ion-channel screening data and consequences for cardiac safety assessment

Keywords: AP(D); Action Potential (Duration); AZ; AstraZeneca; FLIPR; FLuorometric Imaging Plate Reader; GSK; GlaxoSmithKline; HTS; High Throughput Screening [assays]; IC50; Concentration for 50% Inhibition; ICaL; L-type calcium current; IKr; rapid delayed rectifie

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

New front-end electronics for INO-ICAL experiment

Keywords: RPC; INO; ICAL; HARDROC2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Timing and charge measurement of single gap resistive plate chamber detectors for INO-ICAL experiment

Keywords: ICAL; Timing; Gaseous detector; RPC;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice

Keywords: CVDs; cardiovascular diseases; MI; myocardial infarction; DSS; Danshensu; TMP; tetramethylpyrazine; VEGF; vascular endothelial growth factor; VSMCs; vascular smooth muscle cells; HUVECs; human umbilical vein endothelial cells; ICaL; L-type Ca2+ current; C

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The cysteine-rich whey protein supplement, Immunocal®, preserves brain glutathione and improves cognitive, motor, and histopathological indices of traumatic brain injury in a mouse model of controlled cortical impact

Keywords: BBB; blood brain barrier; BBBD; blood brain barrier disruption; EAAC1; excitatory amino acid carrier type 1; GFAP; glial fibrillary acidic protein; GSH; reduced glutathione; GSSG; oxidized glutathione; HPLC-ECD; high performance liquid chromatography with

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Performance study of glass RPC detectors for INO-ICAL experiment

Keywords: INO; ICAL; RPC;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Role of NOD1 in Heart Failure Progression via Regulation of Ca2+ Handling

Keywords: calcium; cardiac arrhythmia; cardiac dysfunction; innate immune system; myocardial infarction; ryanodine receptor; [Ca2+]i; intracellular Ca2+ concentration; CaMKII; calcium/calmodulin-dependent protein kinase II; CMR; cardiac magnetic resonance; EC; exci

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Eplerenone Reduces Atrial Fibrillation Burden Without Preventing Atrial Electrical Remodeling

Keywords: aldosterone; atrial dilation; atrial fibrillation progression; fibrosis; upstream therapy; 7d-PeAF; first 7-day persistent atrial fibrillation episode; 11b-HSD2; 11β-hydroxysteroid dehydrogenase type 2; 12h-AF; first 12-h atrial fibrillation episode; AF;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Development and characterization of single gap glass RPC

Keywords: INO; ICAL; RPC; Leakage current; Efficiency;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The prospective IQ-CSRC trial: A prototype early clinical proarrhythmia assessment investigation for replacing the ICH E14 thorough QTc (TQT) study

Keywords: AP; cardiac action potential; CiPA; comprehensive in vitro proarrhythmia assay; CSRC; Cardiac Safety Research Consortium; Cmax; maximal plasma concentration; CTWG; clinical translational working group; DRest; rate-normalized Tpeak − Tend = Tpe inter

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

JPH-2 interacts with Cai-handling proteins and ion channels in dyads: Contribution to premature ventricular contraction-induced cardiomyopathy

Keywords: Ab; antibody; BIN-1; bridging integrator-1; Cavβ2; voltage-gated Ca channel β subunit 2; CICR; Ca-induced Ca release; CON; control; CSQ2; calsequestrin 2; ICaL; L-type Ca channel current; IKs; slow delayed rectifier current; IP; immunoprecipitate; JPH-2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes

Keywords: LQTS; long-QT syndrome; VM; ventricular myocyte; APD; Action potential duration; IKr; rapidly activating delayed rectifier current; IKs; slowly activating delayed rectifier current; INaL; late (persistent) sodium current; ICaL; L-type calcium current; NCX

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes

Keywords: AP; action potential; APD50; action potential duration at 50% repolarization; CaT; Ca2 + transient; CaTA; Ca2 + transient amplitude; LV; left ventricle; Ito; transient outward current; IKur; ultra-rapidly rectifying current; ICaL; L-type Ca2 + current;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation

Keywords: Comprehensive in vitro Proarrhythmia Assay (CiPA); Field potential data sampling and analysis; Induced pluripotent cell cardiomyocytes (hiPSC-CMs); Multi electrode array (MEA); Patch clamp technologies; Pending issues and solutions; Validation; Voltage se

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of 3 mm glass electrodes and development of RPC detectors for INO-ICAL experiment

Keywords: INO; ICAL; RPC; GLASS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

Keywords: AP(D); action potential (duration); AZ; AstraZeneca; B&Q2; IonWorks Barracuda and second Quattro screening dataset; GLP; good laboratory practice; GSK; GlaxoSmithKline; IC50; concentration for 50% inhibition; ICaL; long-lasting-type calcium current; IKr;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Modulation of KCNQ1 alternative splicing regulates cardiac IKs and action potential repolarization

Keywords: AP; action potential; APD; action potential duration; CL; cycle length; EAD; early afterdepolarization; ECG; electrocardiogram; Endo; endocardial; Epi; epicardial; ICaL; L-type calcium current; IKs; slow delayed-rectifier potassium current; ISO; isoproter

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Electronics and data acquisition system for the ICAL prototype detector of India-based neutrino observatory

Keywords: India-based Neutrino Observatory; INO; ICAL; Electronics; Data acquisition; VME;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Development of 2 m×2 m size glass RPCs for INO

Keywords: INO; ICAL; Glass RPCs; SF6

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Cosmic ray test of INO RPC stack

Keywords: INO; ICAL; RPC stack; Cosmic ray test

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Toward the implementation of the trigger scheme for the ICAL detector of India-based Neutrino Observatory

Keywords: India-based Neutrino Observatory; INO; ICAL; Trigger;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Development of trigger scheme for the ICAL detector of India-based Neutrino Observatory

Keywords: India-based Neutrino Observatory; INO; ICAL; Trigger

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Arrhythmogenic mechano-electric heterogeneity in the long-QT syndrome

Keywords: Long-QT syndrome; Electromechanical window; Calcium; Aftercontractions; Torsades de pointes; Ventricular arrhythmia; AP; action potential; APD; action-potential duration; CaMKII; Ca2+/Calmodulin-dependent serine-threonine protein kinase II; CaM; Ca2+/Calm

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Theoretical investigation of action potential duration dependence on extracellular Ca2+ in human cardiomyocytes

Keywords: AP, Action Potential; APD, Action Potential Duration; APDR, Action Potential Duration Restitution; APD90, Action Potential Duration to 90% of repolarization; DI, Diastolic Interval; endo, endocardial; epi, epicardial; GKs, maximal conductance of IKs; ICaL

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Model systems for the discovery and development of antiarrhythmic drugs

Keywords: Arrhythmias; Ion channel blockers; Ion currents; Reentry; AF; atrial fibrillation; APD; action potential duration; CAVB; chronic atrio-ventricular block; CHF; congestive heart failure; DAD; delayed afterdepolarization; EAD; early afterdepolarization; hERG

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه