دانلود مقالات ISI درباره Ich, International Conference On Harmonisation + ترجمه فارسی

آزمایش خون خشک شده برای اندازه گیری فنیتوین با استفاده از اسپکترومتری کروماتوگرافی مایع

Dried blood spot assay for the quantification of phenytoin using Liquid Chromatography-Mass Spectrometry

Keywords: PHT, phenytoin; TDM, therapeutic drug monitoring; DBS, dried blood spot; LC-MS/MS, liquid chromatography-tandem mass spectrometry; Hct, hematocrit; ICH, International Conference on Harmonisation; LOD, limit of detection; LOQ, limit of quantitationPhenytoi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

تاثیر مواد میکرو کریستالی سلولز: مطالعه موردی بر گرانولاسیون پیچ دوقلو

Impact of microcrystalline cellulose material attributes: A case study on continuous twin screw granulation

Keywords: DPMO, defects per million opportunities; FDA, Food and Drug Administration; H, Hausner ratio; HPC, hydroxypropylcellulose; HPMC, hydroxypropylmethylcellulose; ICH, International Conference on Harmonisation; MCC, microcrystalline cellulose; MLR, multiple l

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

فرمولاسیون و فاکتورهای فرآیندی که بر کیفیت محصول اثر می گذارند و عملکردهای پماد موضعی آن در شرایط آزمایشگاهی است

Formulation and process factors influencing product quality and in vitro performance of ophthalmic ointments

Keywords: BE, bioequivalence; CMA, critical material attributes; CPP, critical process parameters; CQA, critical quality attributes; DoE, design of experiments; HSV, herpes simplex virus; ICH, international conference on harmonisation; IVRT, in vitro release testin

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

تأثیر خواص مواد خام بر ویژگی های کیفیت بحرانی گرانول ها و قرص های تولید شده به طور مداوم

Influence of raw material properties upon critical quality attributes of continuously produced granules and tablets

Keywords: ICH, International Conference on Harmonisation; PAT, Process Analytical Technology; API, Active Pharmaceutical Ingredient; BET, Brunauer–Emmett–Teller; CQA, critical quality attributes; FDA, food and drug administration; HPMC, hydroxypropylmethylcellulose

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Toxicokinetics and toxicity of atorvastatin in dogs

Keywords: p-OH ATV, p-hydroxyatorvastatin; o-OH ATV, o-hydroxyatorvastatin; ICH, International Conference on Harmonisation; NC3Rs, National Centre for the Replacement, Refinement & Reduction of Animals in Research; GPR, G-protein coupled receptor; CYP, cytochrome P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies

Keywords: 6-TG, 6-thioguanine; Cm, chloramphenicol; ICH, International Conference on Harmonisation; MF, mutant frequency; OECD, Organisation for Economic Co-operation and Development; CDER, Center for Drug Evaluation and Researchgpt delta transgenic rat; Phenacetin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

How do the top 12 pharmaceutical companies operate safety pharmacology?

Keywords: ICH, International Conference on Harmonisation; FTEs, full time equivalents; R&D, Research & development; PK/PD, pharmacokinetic/pharmacodynamic; PhD, Doctor of PhilosophyPharmaceutical company; Drug discovery; Drug development

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Detecting drug-induced prolongation of the QRS complex: New insights for cardiac safety assessment

Keywords: bpm, beats per minute; Cmax, maximal plasma concentration; ECG, electrocardiogram; HR, heart rate; hERG, human ether-à-go-go gene; hNav1.5, human cardiac Na channels; ICH, International Conference on Harmonisation; INa, sodium current; TdP, Torsades de po

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of the physical properties and stability of two lipid drug delivery systems containing mefloquine

Keywords: CLSM, Confocal laser scanning microscopy; %EE, Percentage entrapment efficacy; FSC, Forward light scattering; ICH, International Conference on Harmonisation; MQ, Mefloquine hydrochloride; PBS, Phosphate buffer saline; RH, Relative humidity; WHO, World Hea

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Working in partnership to advance the 3Rs in toxicity testing

Keywords: 3Rs, Replacement, Reduction, Refinement; BBSRC, Biotechnology and Biological Sciences Research Council; BTS, British Toxicology Society; ICH, International Conference on Harmonisation; mAb, monoclonal antibody; NC3Rs, National Centre for the Replacement,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Potential bias and mitigations when using stable isotope labeled parent drug as internal standard for LC–MS/MS quantitation of metabolites

Keywords: APCI, atmospheric pressure chemical ionization; AUC, area under the curve; ESI, electrospray ionization; FDA, Food and Drug Administration; HILIC, hydrophilic interaction chromatography; HQC, high QC; ICH, international conference on harmonisation; J&J PR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

A framework to assess the translation of safety pharmacology data to humans

Keywords: ADRs, Adverse drug reactions; NCE, New chemical entity; FDA, Food and Drug Administration; hERG, Human Ether-a-go-go Related Gene; FTIM, First Time In Man; HESI, Health and Environmental Science Institute; ICH, International Conference on Harmonisation; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه