
Metabolic engineering of Chinese hamster ovary cells: Towards a bioengineered heparin
Keywords: GAG, glycosaminoglycan; IdoA, l-iduronic acid; GlcA, d-glucuronic acid; GlcNAc, N-acetyl-d-glucosamine; CHO, Chinese hamster ovary; HS, heparan sulfate; ATIII, antithrombin III; Ext, exostosin; Ndst, N-deacetylase/N-sulfotransferase; Hs6st, heparan sulfat