Keywords: IF، رشته متوسط; CmC, chloro-m-cresol; IF, intermediate filament; SNP, single nucleotide polymorphism; SR, sarcoplasmic reticulum; TMRE, tetramethylrhodamine, ethyl ester, perchlorate; WT, wild type miceCalcium; Desmin; Mitochondria; Myotube; Satellite cell
مقالات ISI IF، رشته متوسط (ترجمه نشده)
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Keywords: IF، رشته متوسط; IF, intermediate filament; NSCs, neural stem cells; NPCs, neural progenitor cells; E8.5, embryonic day 8.5; WT, wild type; TG, transgenic; PI3K, phosphoinositide 3-kinaseNestin; Embryonic development; Heart; Forebrain; Cell proliferation; PI3K/Akt pathway
Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease
Keywords: IF، رشته متوسط; AD, Alzheimer's disease; Aβ, amyloid-beta; APP, amyloid precursor protein; GABA, gamma-aminobutyric acid; GFAP, glial fibrillary acidic protein; IF, intermediate filament; VIM, vimentin; TNFα, tumor necrosis factor α; BBB, blood brain barrier; EC, entorhi
Heterogeneity in the properties of NEFL mutants causing Charcot–Marie–Tooth disease results in differential effects on neurofilament assembly and susceptibility to intervention by the chaperone-inducer, celastrol
Keywords: IF، رشته متوسط; NF, neurofilaments; IF, intermediate filament; NEFL, neurofilament light protein; NEFH, neurofilament heavy protein; NEFM, neurofilament medium protein; CMT, Charcot–Marie–Tooth disease; BN-PAGE, Blue Native Polyacrylamide Gel Electrophoresis; PDVF, polyv
Structural and physiological phenotypes of disease-linked lamin mutations in C. elegans
Keywords: IF، رشته متوسط; dsRNA, double stranded RNA; EDMD, Emery–Dreifuss muscular dystrophy; ET, electron tomography; IF, intermediate filament; TEM, transmission electron microscopyLaminopathic diseases; Nuclear lamina; EDMD; HGPS; Caenorhabditis elegans
Stabilization of vimentin coil2 fragment via an engineered disulfide
Keywords: IF، رشته متوسط; IF, Intermediate filament; CC, Coiled coil; SeMet, Selenomethionine; PDB, Protein data bank; MAD, Multiple-wavelength anomalous dispersion; OD, Optical density; IPTG, Isopropyl-β-d-thio-galactoside; Tris, Tris(hydroxymethyl)aminomethane; TEV, Tobacco etch
Looking back at a quarter-century of research at the Maurice E. Müller Institute for Structural Biology
Keywords: IF، رشته متوسط; 2D, two-dimensional; 3D, three-dimensional; AFM, atomic force microscope/microscopy; AQP, aquaporin; EM, electron microscope/microscopy; IF, intermediate filament; MIH, Maurice E. Müller Institute for High-Resolution Electron Microscopy/Maurice E. Müller
Cytokeratin 18-mediated disorganization of intermediate filaments is induced by degradation of plectin in human liver cells
Keywords: IF، رشته متوسط; MT, microtubule; MF, microfilament; IF, intermediate filament; CK, cytokeratin; IFAP, intermediate filament associated protein; HCC, hepatocellular carcinoma; HRP, horseradish peroxidase; DMEM, Dulbecco’s minimum essential medium; FBS, fetal bovine serum;
Identification of in vivo released products of Onchocerca with diagnostic potential, and characterization of a dominant member, the OV1CF intermediate filament
Keywords: IF، رشته متوسط; OOTE, O. volvulus total extract; ESP, excretory/secretory products; Mab, monoclonal antibody; IF, intermediate filament; IFs, intermediate filaments; NRP, nodular released products; mf, microfilaria; PBS, phosphate buffered saline; FCS, fetal calf serum;
Nuclear positioning: Mechanisms and functions
Keywords: IF، رشته متوسط; ABD, actin-binding domain; APC, adenomatous polyposis coli; EDMD, Emery–Dreifuss muscular dystrophy; IF, intermediate filament; KASH, Klarsicht ANC-1 and SYNE Homology; LINC, LInkers of the Nucleoskeleton to the Cytoskeleton; LIS1, Lissencephaly-1; MT, mi
Plectin interacts with the rod domain of type III intermediate filament proteins desmin and vimentin
Keywords: IF، رشته متوسط; AD, activation domain; BD, binding domain; EBS-MD, epidermolysis bullosa simplex associated with muscular dystrophy; GFP, green fluorescent protein; GST, glutathione-S-transferase; IF, intermediate filament; mAb, monoclonal antibody; Y2H, yeast two-hybrid
Crystal Structure of a Rigid Four-Spectrin-Repeat Fragment of the Human Desmoplakin Plakin Domain
Keywords: IF، رشته متوسط; IF, intermediate filament; DP, desmoplakin; SR, spectrin repeat; BPAG1, bullous pemphigoid antigen 1; SAD, single-wavelength anomalous dispersion; ARVD/C, arrhythmogenic right ventricular dysplasia/cardiomyopathy; PDB, Protein Data Bankdesmoplakin; spectr
Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability
Keywords: IF، رشته متوسط; IF, intermediate filament; sHSPs, small heat shock proteins; GFAP, glial fibrillary acidic protein; TEM, transmission electron microscopy; ULF, unit length filament; WT, wild typeGFAP; Mutation; Alexander disease; Intermediate filament; Stress; Small heat
GFAP in health and disease
Keywords: IF، رشته متوسط; GFAP, glial fibrillary acidic protein; IF, intermediate filament; CNS, central nervous system; MS, multiple sclerosis; aa, amino acid; AxD, Alexander disease; AD, Alzheimer's disease; DS, Down syndrome; VZ, ventricular zone; gw, gestational week; SVZ, sub
Severe Myopathy Mutations Modify the Nanomechanics of Desmin Intermediate Filaments
Keywords: IF، رشته متوسط; IF, intermediate filament; MPL, mass per length; AFM, atomic force microscopy; EM, electron microscopy; FWHM, full width at half maximumatomic force microscopy; coiled-coil interactions; molecular slippage; desminopathy; myofibrillar myopathy
Desmin and Vimentin Intermediate Filament Networks: Their Viscoelastic Properties Investigated by Mechanical Rheometry
Keywords: IF، رشته متوسط; IF, intermediate filament; LS, low salt; HS, high saltdesmin and vimentin intermediate filament; electron microscopy; rheology; persistence length; strain stiffening
The Supramolecular Organization of the C. elegans Nuclear Lamin Filament
Keywords: IF، رشته متوسط; IF, intermediate filament; cryo-ET, cryo-electron tomographyC. elegans, cryo-electron tomography, intermediate filaments, lamin
Mutation in keratin 18 induces mitochondrial fragmentation in liver-derived epithelial cells
Keywords: IF، رشته متوسط; CB, cytochalasin B; DMSO, dimethyl sulfoxide; Drp1, dynamin-related protein 1; FRAP, fluorescence recovery; GFP, green fluorescent protein; IF, intermediate filament; K, keratin; MF, microfilament; MT, microtubule; OPA1, optic atrophy 1; WT, wild typeCyto
Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization
Keywords: IF، رشته متوسط; CK8, cytokeratin 8; CK18, cytokeratin 18; IF, intermediate filament; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; NPC, nasopharyngeal carcinomaCisplatin resistance; Cytokeratin 8; Nasopharyngeal carcinoma; Proteomics; Apoptosis
Bone marrow stromal cells reduce ischemia-induced astrocytic activation in vitro
Keywords: IF، رشته متوسط; bone marrow stromal cell; astrocyte; stroke; IL-6; IL-6 receptor; gp130BMSC, bone marrow stromal cell; DMEM, Dulbecco’s modified eagle medium; FBS, fetal bovine serum; GFAP, glial fibrillary acidic protein; IF, intermediate filament; IL-6R, IL-6 receptor;
Keratin Mutation Predisposes to Mouse Liver Fibrosis and Unmasks Differential Effects of the Carbon Tetrachloride and Thioacetamide Models
Keywords: IF، رشته متوسط; Ab, antibody; CCl4, carbon tetrachloride; h, human; H&E, hematoxylin and eosin; Hsp, heat shock protein; IF, intermediate filament; MMP, matrix metalloproteinase; RT-PCR, reverse-transcription polymerase chain reaction; TAA, thioacetamide; TIMP, tissue in
Plectin deficiency affects precursor formation and dynamics of vimentin networks
Keywords: IF، رشته متوسط; Cdk1, cyclin dependent kinase 1; GFP, green fluorescent protein; IF, intermediate filament; NuMA, nuclear mitotic apparatus protein; Plk1, polo-like kinase 1Plectin; Vimentin; Squiggles; IF dynamics; Motility
Genetically engineered mouse models for skin research: Taking the next step
Keywords: IF، رشته متوسط; BAC, bacterial artificial chromosome; EHK, epidermolytic hyperkeratosis; ES cell, embryonic stem cell; GEM, genetically engineered mouse; GEMM, genetically engineered mouse model; IF, intermediate filament; HSV-TK, herpes simplex virus thymidine kinaseKno
Insights into the beaded filament of the eye lens
Keywords: IF، رشته متوسط; IF, intermediate filament; BFSP1 and 2, beaded filament structural protein 1 and 2; CP49, cytoskeletal protein 49; CP115, cytoskeletal protein 115Intermediate filament; Cataract; CP49; Filensin; Beaded filament
Structural analysis of vimentin and keratin intermediate filaments by cryo-electron tomography
Keywords: IF، رشته متوسط; CEMOVIS, cryo-electron microscopy on vitreous sections; Cryo-EM, cryo-electron microscopy; Cryo-ET, cryo-electron tomography; CTF, contrast transfer function; EM, electron microscopy; IF, intermediate filament; PSF, point-spread function; STEM, scanning t
Transglutaminase 2 Regulates Mallory Body Inclusion Formation and Injury-Associated Liver Enlargement
Keywords: IF، رشته متوسط; Ab, antibody; ALT, alanine aminotransferase; DDC, 3,5-diethoxycarbonyl-1,4-dihydrocollidine; HD, Huntington’s disease; IF, intermediate filament; K, keratin; MB, Mallory body; Mr, molecular mass; R, resolving gel; S, stacking gel; TG, transglutaminase
Towards a molecular description of intermediate filament structure and assembly
Keywords: IF، رشته متوسط; EM, electron microscopy; IF, intermediate filament; MPL, mass-per-length; SAXS, small-angle X-ray scattering; STEM, scanning transmission EM; ULF, unit-length filamentAssembly; Keratin; Intermediate filaments; Polymorphism; Small-angle X-ray scattering; V
Mouse models of the laminopathies
Keywords: IF، رشته متوسط; IF, intermediate filament; INM, inner nuclear membrane; ONM, outer nuclear membrane; NE, nuclear envelope; LMNA, lamin A/C; LMNB, lamin B; EDMD, Emery–Dreifuss muscular dystrophy (X-linked); AD-EDMD, autosomal-dominant EDMD; LMG1B, limb-girdle muscular dy
From Mallory to Mallory–Denk bodies: What, how and why?
Keywords: IF، رشته متوسط; Ab, antibody; ASH, alcoholic steatohepatitis; Atg, autophagy related gene; DDC, 3,5-diethoxycarbonyl-1,4-dihydrocollidine; GF, griseofulvin; Hsp, heat shock protein; IF, intermediate filament; IHBs, intracytoplasmic hyaline bodies; K, keratin; MB, Mallory
Identification of a novel, highly variable amino-terminal amino acid sequence element in the nuclear intermediate filament protein lamin B2 from higher vertebrates
Keywords: IF، رشته متوسط; IF, intermediate filament; MALDI-TOF MS, matrix-assisted laser desorption ionization time-of-flight mass spectrometry; NF-H, heavy neurofilament triplet protein; SDS, sodium dodecyl sulphateIntermediate filaments; Lamin B2; Nuclear envelope
Pharmacologic transglutaminase inhibition attenuates drug-primed liver hypertrophy but not Mallory body formation
Keywords: IF، رشته متوسط; Ab, antibody; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; DDC, 3,5-diethoxycarbonyl-1,4-dihydrocollidine; ECM, extracellular matrix; H&E, hematoxylin and eosin; IF, intermediate filament; Inh, transglutaminas
Exploring the Mechanical Properties of Single Vimentin Intermediate Filaments by Atomic Force Microscopy
Keywords: IF، رشته متوسط; IF, intermediate filament; AFM, atomic force microscopy; ULF, unit-length filaments; MT, microtubule; TEM, transmission electron microscopyvimentin; intermediate filaments; atomic force microscopy; bending stiffness; axial sliding between dimmers; glutara
Impact of Disease Mutations on the Desmin Filament Assembly Process
Keywords: IF، رشته متوسط; IF, intermediate filament; STEM, scanning transmission electron microscopy; ULF, unit-length filament; MPL, mass per length; FWHM, full width at half maximum massintermediate filament; analytical ultracentrifugation; inherited mutations; myofibrillar myop