دانلود مقالات ISI درباره Iks + ترجمه فارسی

Made for “anchorin”: Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons

Keywords: Action potential; M-current; IKS; Benign familial neonatal seizures; Excitozone

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Lysophosphatidylcholine enhances IKs currents in cardiac myocytes through activation of G protein, PKC and Rho signaling pathways

Keywords: LPC; lysophosphatidylcholine; LPC-16; 1-palmitoyl-lysophosphatidylcholine; LPC-6; 1-caproyl-lysophosphatidylcholine; LPC-18:1; 1-oleoyl-lysophosphatidylcholine; PC; phosphatidylcholine; SPC; sphingosylphosphorylcholine; IKs; slow activating component of d

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Partial restoration of the long QT syndrome associated KCNQ1 A341V mutant by the KCNE1 β-subunit

Keywords: Long QT syndrome; IKs; A341V; KCNE1; Arrhythmia; Action potentials;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Structural basis for KV7.1–KCNEx interactions in the IKs channel complex

Keywords: IKs; KCNE1; KCNE2; KCNQ1; KV7.1IKr, cardiac rapid delayed rectifier current; IKs, cardiac slow delayed rectifier current; KV, voltage-gated potassium channel; NMR, nuclear magnetic resonance; PIP2, phosphatidylinositol 4,5-bisphosphate

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking

Keywords: IKs; KCNQ1; S4-S5 linker; Kv gating;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular determinants of Kv1.5 channel block by diphenyl phosphine oxide-1

Keywords: DPO-1; diphenylphosphine oxide-1; APD; action potential duration; IKr; rapid delayed rectifier K+ current; IKs; slow delayed rectifier K+ current; IKur; ultra-rapid delayed rectifier current; IC50; the concentration of drug required for 50% block of curre

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Evaluation of channel function after alteration of amino acid residues at the pore center of KCNQ1 channel

Keywords: Long QT syndrome; Missense mutation; KCNQ1; IKs; Pore center; Amino acid residue

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Blockade of the IKs potassium channel: An overlooked cardiovascular liability in drug safety screening?

Keywords: APD, action potential duration; EAD, early after-depolarisation; hERG, human ether-a-go-go-related gene; HSD-1, 11β-hydroxysteroid dehydrogenase-1; IC50, 50% inhibitory concentration; IKr, rapidly activating delayed inward rectifier potassium channel; IKs

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Models of torsades de pointes: Effects of FPL64176, DPI201106, dofetilide, and chromanol 293B in isolated rabbit and guinea pig hearts

Keywords: STV; short-term variability; Tp-Te; peak to end of T-wave; QTc; corrected QT interval; Chromanol 293B; Dofetilide; DPI201106; FPL64176; IKs; Langendorff; Torsades; QTc; Short-term variability;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Tanshinone IIA: A new activator of human cardiac KCNQ1/KCNE1 (IKs) potassium channels

Keywords: Tanshinone IIA; hKCNQ1/hKCNE1; IKs; Kv1.5; hERG; IK1; HEK 293 cell; Potassium channel; Ion channel; Patch clamp; Human

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Assessing QT prolongation in conscious dogs: Validation of a beat-to-beat method

Keywords: Electrocardiogram; Restitution; Torsades de pointes; Arrhythmia; Autonomic tone; Translation to humans; BPM; beats per minute; ECG; electrocardiogram; IKr; rapid potassium delayed rectifier current; IKs; slow potassium delayed rectifier current; PK; pharm

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Model systems for the discovery and development of antiarrhythmic drugs

Keywords: Arrhythmias; Ion channel blockers; Ion currents; Reentry; AF; atrial fibrillation; APD; action potential duration; CAVB; chronic atrio-ventricular block; CHF; congestive heart failure; DAD; delayed afterdepolarization; EAD; early afterdepolarization; hERG

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Dual roles of the A kinase-anchoring protein Yotiao in the modulation of a cardiac potassium channel: A passive adaptor versus an active regulator

Keywords: IKs; KCNQ1; AKAP; Yotiao; PKA; Phosphorylation; Sympathetic nervous system

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Modulation of functional properties of KCNQ1 channel by association of KCNE1 and KCNE2

Keywords: IKs; KCNE1; KCNE2; KCNQ1; Mefenamic acid; Long QT syndrome; K+ channel; Heart; Patch–clamp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Both β-adrenergic receptor stimulation and cardiac tissue type have important roles in elucidating the functional effects of IKs channel blockers in vitro

Keywords: IKs; IKr; Action potential duration (APD); IKs channel blockers; Triangulation; Tissue-specific difference; β-adrenoceptor receptor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Nonclinical proarrhythmia models: Predicting Torsades de Pointes

Keywords: AP; Action potential; APD; Action potential duration; APD90; Action potential duration at 90% repolarization; A-V; Atrioventricular; CAVB; Chronically A-V block; CV; Conduction velocity; EADs; Early after-depolarizations; ECG; Electrocardiogram; hERG; Hum

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه