Allosteric Switching of Agonist/Antagonist Activity by a Single Point Mutation in the Interluekin-1 Receptor Antagonist, IL-1Ra
Keywords: IL, interleukin; IL-1R, IL-1 receptor; IL-1Ra, IL-1 receptor antagonist; IL-1RAcP, IL-1R accessory protein; WT, wild type; HDX, hydrogen–deuterium exchange; HSQC, heteronuclear single quantum coherence; MEF, mouse embryonic fibroblast; EMSA, electrophoret