Keywords: IL-2، اینترلوکین-2; FKBP12, FK506 binding protein; IL-2, interleukin-2; PP2B, calcineurin phosphatase; PLGA, poly-d,l-lactic-co-glycolic acidBiodegradable microspheres; Calcineurin phosphatase; Interleukin-2; Rats and tacrolimus
مقالات ISI IL-2، اینترلوکین-2 (ترجمه نشده)
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Keywords: IL-2، اینترلوکین-2; GVHD, graft-versus-host disease; GFP, green fluorescent protein; HSCs, hematopoietic stem cells; HSCT, hematopoietic stem cell transplantation; IFN-γ, interferon-γ; IL-2, interleukin-2; IL-4, interleukin-4; MST, median survival time; MLR, mixed lymphocyte
Keywords: IL-2، اینترلوکین-2; CI, confidence interval; CSF, colony-stimulating factor; HBsAg, hepatitis B virus surface antigen; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HR, Hazard Ratio; IL, Interleukin; IL-1B b, Interleukin-1 beta; IL-2, Interleukin-2; IL-4, Interleuki
Structural analysis and immunoregulation activity comparison of five polysaccharides from Angelica sinensis
Keywords: IL-2، اینترلوکین-2; CAPS, Chinese Angelica sinensis polysaccharide; ConA, Concanavalin A; TNF-α, tumor necrosis factor-alpha; IFN-γ, interferon-γ; IL-2, interleukin-2; FT-IR, Fourier transform infrared; HPGPC, high performance gel permeation chromatography; GC–MS, gas chroma
Deoxynivalenol-induced cytokines and related genes in concanavalin A-stimulated primary chicken splenic lymphocytes
Keywords: IL-2، اینترلوکین-2; DON, Deoxynivalenol; ConA, concanavalin A; IL-1β, interleukin-1beta; IL-12β, interleukin-12 beta; Th1, T Helper Type 1; IL-2, interleukin-2; Th 2, T Helper Type 2; IL-1RI, interleukin-1 receptor I; IL-4, interleukin-4; IL-6, interleukin-6; IL-10, interleu
Augmentation of natural killer cell activity in vitro and in vivo by sericin-derived oligopeptides
Keywords: IL-2، اینترلوکین-2; BW, body weight; ConA, Concanavalin A; ELISA, enzyme-linked immunosorbent assay; GC/MS, gas chromatography/mass spectrometry; IFN-γ, interferon-γ; IL-2, interleukin-2; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NK, natural killer;
Thymic B cells promote thymus-derived regulatory T cell development and proliferation
Keywords: IL-2، اینترلوکین-2; Thymic B cells; Thymic Treg cells; Development; Proliferation; Cell–cell contactTreg cells, regulatory T cells; μMT, immunoglobulin heavy chain of the class mu knockout mice; IL-7, interleukin-7; IL-2, interleukin-2; MOG, myelin oligodendrocyte glycoprote
Effects of polysaccharide on chicks co-infected with Bordetella avium and Avian leukosis virus
Keywords: IL-2، اینترلوکین-2; TPPPS, Taishan Pinus massoniana pollen polysaccharide; ALV-B, subgroup B Avian leukosis virus; B. avium, Bordetella avium; IL-2, interleukin-2; IFN-γ, interferon-γ; LTR, lymphocyte transformation rate; p27, group-specific antigen; ConA, concanavalin A; TF
Synergistic immunosuppressive effects of the mTOR inhibitor sirolimus and the phytochemical curcumin
Keywords: IL-2، اینترلوکین-2; C, controls; Con A, concanavalin A; DMSO, dimethylsulfoxide; ELISA, enzyme-linked immunosorbent assay; FACS, fluorescence activated cell scanner; IC50, halfmaximal inhibitory concentration; IL-2, interleukin-2; IκB, inhibitor of κB; mTOR, mammalian target
Current Status of Immunosuppression in Liver Transplantation
Keywords: IL-2، اینترلوکین-2; liver transplantation; immunosuppression; metabolic syndromeHLA, human leukocyte antigen; MAP, mitogen activated protein; NF-kB, nuclear factor kappa B; IL-2, interleukin-2; CNI, Calcineurin inhibitor; NFAT, nuclear factor of activated T cells; FKBP12, FK
Validated detection of anti-GD2 antibody ch14.18/CHO in serum of neuroblastoma patients using anti-idiotype antibody ganglidiomab
Keywords: IL-2، اینترلوکین-2; mAb, monoclonal antibody; NB, neuroblastoma; AIT, anti-idiotype; ELISA, enzyme-linked immunosorbent assay; QC, quality controls; LOD, limit of detection; IL-2, interleukin-2; DMEM, modified Eagle's medium; BSA, bovine serum albumin; HRP, horseradish perox
Deciphering the molecular bases of the biological effects of antibodies against Interleukin-2: A versatile platform for fine epitope mapping
Keywords: IL-2، اینترلوکین-2; aa, amino acid; Abs, absorbance; Ag, antigen; ELISA, enzyme-linked immunosorbent assay; hIL-2, human IL-2; IL-2, Interleukin-2; IPTG, isopropyl-β-d-thiogalactopyranoside; mAb, monoclonal antibody; mIL-2, mouse IL-2; PBS, phosphate buffered saline; RT, roo
Increased numbers and suppressive activity of regulatory CD25+CD4+ T lymphocytes in the absence of CD4 engagement by MHC class II molecules
Keywords: IL-2، اینترلوکین-2; Ab, antibody; AICD, activation-induced cell death; APC, antigen-presenting cell; FITC, fluorescein isothiothyanate; IFN, interferon; IL-2, interleukin-2; MHC, major histocompatibility complex; Ova323, ovalbumin peptide 323-339; R-PE, phycoerythrin; SEA, S
WISH cell line: From the antiviral system to a novel reporter gene assay to test the potency of human IFN-α and IFN-β
Keywords: IL-2، اینترلوکین-2; AVA, antiviral activity assay; eGFP, enhanced green fluorescent protein; FSC, forward scatter; G-CSF, granulocyte-colony stimulating factor; GM-CSF, granulocyte macrophage-colony stimulating factor; IFN, interferon; IL-2, interleukin-2; ISRE, IFN sensitiv
Manganese promotes phorbol ester-induced interleukin-2 production via AP-1 activation in Jurkat T-cells
Keywords: IL-2، اینترلوکین-2; AP-1, activator protein-1; ConA, concanavalin A; IL-2, interleukin-2; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase; NFAT, nuclear factor of activated T-cells; NFκB, nuclear factor kappa B
Upfront Denileukin Diftitox as in vivo regulatory T-cell depletion in order to enhance vaccination effects in a canine allogeneic hematopoietic stem cell transplantation model
Keywords: IL-2، اینترلوکین-2; CSA, cyclosporine A; DCs, dendritic cells; DD, Denileukin Diftitox; DLA, dog leukocyte antigen; GVHD, graft-versus-host disease; HSCT, hematopoietic stem cell transplantation; IL-2, interleukin-2; MMF, mycophenolate mofetil; MLR, mixed lymphocyte reaction
Intravitreous interleukin-2 treatment and inflammation modulates glial cells activation and uncrossed retinotectal development
Keywords: IL-2، اینترلوکین-2; IL-2; critical period; development; superior colliculus; plasticity; glial cellsDAPI, 4′,6-diamidino-2-phenylindole; GFAP, glial fibrillary acidic protein; HRP, horseradish peroxidase; IL-2, interleukin-2; LTD, long-term depression; LTP, long-term potenti
JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation
Keywords: IL-2، اینترلوکین-2; Treg, regulatory T cells; TCR, T cell receptor; TGF-β, transforming growth factor; IL-2, interleukin-2; ChIP, chromatin immunoprecipitationFoxp3; Transcription; TCR; TGF-β; IL-2; Epigenetics; JunB; c-Rel
Transient proteasome inhibition as a strategy to enhance lentiviral transduction of hematopoietic CD34+ cells and T lymphocytes: Implications for the use of low viral doses and large-size vectors
Keywords: IL-2، اینترلوکین-2; CB, cord blood; eGFP, enhanced green fluorescent protein; FL, flt3/flk2 ligand; HSC, hematopoietic stem cells; HLA, human leukocyte antigen; IL-6, interleukin-6; IL-2, interleukin-2; LV, lentiviral vectors; MLR, mixed lymphocyte reaction; MOI, multiplicit
Characterization of protoberberine analogs employed as novel human P2X7 receptor antagonists
Keywords: IL-2، اینترلوکین-2; ATP, adenosine-5-triphosphate; BzATP, 2′(3′)-O-(4-benzoylbenzoyl)-ATP; ELISA, enzyme-linked immunosorbent assay; ERK1/2, extracellular signal-regulated kinases 1/2; IFN-γ, interferon-γ; IL-1β, interleukin-1β; IL-2, interleukin-2; KN62, 1-[N,O-bis(5-isoqui
Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture
Keywords: IL-2، اینترلوکین-2; PBMC, peripheral blood mononuclear cells; mAb, monoclonal antibody; HUVEC, human umbilical vein endothelial cell(s); IL-6, interleukin-6; IL-8, interleukin-8; TNFα, tumour necrosis factor alpha; IL-2, interleukin-2; IFNγ, interferon gamma; vWF, von Willeb
TRP expression pattern and the functional importance of TRPC3 in primary human T-cells
Keywords: IL-2، اینترلوکین-2; APC, antigen-presenting cells; [Ca2+]i, intracellular Ca2+ concentration; CRAC channel, Ca2+ release-activated Ca2+ channel; IL-2, interleukin-2; IS, immunological synapse; o/n, over night; NCX, Na+/Ca2+ exchanger; PBLs, peripheral blood lymphocytes; RNAi
Phosphorylation at serine 318 is not required for inhibition of T cell activation by ALX
Keywords: IL-2، اینترلوکین-2; TCR, T cell receptor; IL-2, interleukin-2; WT, wild-type; PAGE, polyacrylamide gel electrophoresis; LC, liquid chromatography; MS, mass spectrometryT cell; Adaptor; ALX; Phosphorylation
Antioxidative and immunoprotective effects of Pyracantha fortuneana (Maxim.) Li polysaccharides in mice
Keywords: IL-2، اینترلوکین-2; DMSO, dimethyl sulphoxide; SOD, superoxide dismutase; GSH-PX, glutathione peroxidase; MDA, malondialdehyde; NK, natural killer cells; PFP, Pyracantha fortuneana (Maxim.) Li polysaccharides; IL-2, interleukin-2; IL-6, interleukin-6; TNF-α, tumor necrosis f
Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes—A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies
Keywords: IL-2، اینترلوکین-2; PNP, purine nucleoside phosphorylase; dGuo, deoxyguanosine; dGTP, deoxyguanosine triphosphate; dCyK, deoxycytidine kinase; dGMP, deoxyguanosine monophosphate; IL-2, interleukin-2; Con A, concanavalin A; dCyt, deoxycytidine; CPT, cell preparation tubes; PB
IKK antagonizes activation-induced cell death of CD4+ T cells in aged mice via inhibition of JNK activation
Keywords: IL-2، اینترلوکین-2; IKK, IκB kinase; JNK, c-Jun N-terminal protein kinase; AICD, activation-induced cell death; IL-2, interleukin-2; TNF-α, tumor necrosis factor alpha; IL-6, interleukin-6; FADD, Fas-associated protein with death domain; c-FLIP, caspase-8 (FLICE)-like inhibi
Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4+ T cells
Keywords: IL-2، اینترلوکین-2; cAMP, cyclic adenosine monophosphate; Treg, regulatory T cells; Tcon, conventional T cells; PDE, phosphodiesterase; AC, adenylyl cyclase; IL-2, interleukin-2; mAbs, monoclonal Abs; ddADO, 2′,3′-dideoxy-adenosine; Dip, DipyridamoleCyclic adenosine monophos
Phenyl methimazole suppresses dextran sulfate sodium-induced murine colitis
Keywords: IL-2، اینترلوکین-2; C10, phenyl methimazole (compound 10); DMSO, dimethyl sulfoxide; DSS, dextran sulfate sodium; IL-1β, interleukin-1β; IL-2, interleukin-2; IL-6, interleukin-6; IL-12, interleukin-12; IP-10, interferon inducible protein-10; PBS, phosphate buffered saline; T
Molecular therapeutic approaches to melanoma
Keywords: IL-2، اینترلوکین-2; FDA, federal food and drug administration; IL-2, interleukin-2; DTIC, alkylating agent dacarbazine; BCNU, carmustine; RTK, receptor tyrosine kinase; SCF, stem cell factor; MAPK, mitogen-activated protein kinase; PI3K/AKT, phosphoinositide 3-kinase/serine-
Plant lectins: Potential antineoplastic drugs from bench to clinic
Keywords: IL-2، اینترلوکین-2; AKT, serine/threonine-specific protein kinase; CBL, Canavalia brasiliensis lectin; CKL, Cladrastis kentukea lectin; ConA, concanavalin A; DGL, Dioclea grandiflora lectin; GNA, Galanthus nivalis agglutinin; IL-2, interleukin-2; KM, Korean mistletoe; LNL, L
Surgical Resection of Renal Cell Carcinoma After Targeted Therapy
Keywords: IL-2، اینترلوکین-2; kidney; carcinoma; renal cell; complications; angiogenesis inhibitors; antineoplastic agentsCT, computerized tomography; EBL, estimated blood loss; IL-2, interleukin-2; RCC, renal cell carcinoma
Effect of naturally occurring hydroxychavicol acetate on the cytokine production in T helper cells
Keywords: IL-2، اینترلوکین-2; ACA, acetoxychavicol acetate; HCA, hydroxychavicol acetate; Th cell, T helper cell; IL-2, interleukin-2; IFNγ, interferon γ; T-bet, T-box protein expressed in T cellsAcetoxychavicol acetate; Hydroxychavicol acetate; T helper cell; IL-2; IFNγ; T-bet
A cell-based screening assay for Natural Killer cell activity
Keywords: IL-2، اینترلوکین-2; CFDA-SE, Carboxyfluorescein Diacetate Succinimidyl Ester; NK, Natural Killer cells; IL-2, Interleukin-2; PBMC, peripheral mononuclear blood cells; PI, propidium iodideFresh PBMC; Cell-based assay; Natural Killer cytolytic activity; Flow cytometry; Screeni
The combination of IL-21 and IFN-α boosts STAT3 activation, cytotoxicity and experimental tumor therapy
Keywords: IL-2، اینترلوکین-2; IL-2, interleukin-2; IFN-α, interferon-α; TNF-αR, TNF-α receptor; γc, common gamma chain; STAT, signal transducers and activators of transcription; Ab, antibody; PBMCs, peripheral blood mononuclear cells; MLC, mixed lymphocyte culture; PY-STAT, tyrosine-p
Genomic organization and functional characterization of the promoter for the human suppressor of cytokine signaling 6 gene
Keywords: IL-2، اینترلوکین-2; 5-aza-dC, 5-aza-2'-deoxycytidine; CRC, colorectal cancer; CT, threshold cycle; DMEM, Dulbecco’s modified Eagle medium; EST, Expressed sequence tags; GC, gastric cancer; GH, growth hormone; HEK, human embryonic kidney; IL-2, interleukin-2; IR, insulin rece
Comprehensive analysis of NK cell function in whole blood samples
Keywords: IL-2، اینترلوکین-2; IFNγ, interferon-γ; IL-2, interleukin-2; NK cell, natural killer cell; PBMC, peripheral blood mononuclear cellsCytokines; Cytotoxicity; Functional analysis; Human; Natural killer cells; Surface receptor; Whole blood
Select phytochemicals suppress human T-lymphocytes and mouse splenocytes suggesting their use in autoimmunity and transplantation
Keywords: IL-2، اینترلوکین-2; T-cell, T-lymphocyte; IL-2, interleukin-2; EGCG, epigallocatechin gallate; PBMC, peripheral blood mononuclear cells; SEM, standard error of the mean; NF-κB, nuclear factor κB; NF-AT, nuclear factor of activated T cellsImmunosuppression; Healthy dietary nu
Quantitative analysis of cytokine-induced vascular toxicity and vascular leak in the mouse brain
Keywords: IL-2، اینترلوکین-2; IL-2, interleukin-2; VLS, vascular leak syndrome; NO, nitric oxide; MRI, magnetic resonance imaging; BBB, blood-brain barrier; NaFl, sodium fluorescein; Iso-B4, isolectin GS-IB4; vWF, von Willebrand Factor; ROI, region of interest; SI, signal intensity; P
High-level transfection of primary rabbit T lymphocytes
Keywords: IL-2، اینترلوکین-2; PI, propidium iodide; CD, cluster of differentiation; HIV, human immunodeficiency virus; Nef, negative factor; PHA, Phytohaemagglutinin; Con A, Concanavalin A; IL-2, interleukin-2; GFP, green fluorescent protein; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diph
Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita
Keywords: IL-2، اینترلوکین-2; AV, Artemisia vestita; Con A, concanavalin A; Dex, dexamethasone; DTH, delayed-type hypersensitivity; ES-MS, electrospray mass spectrometry; HPLC, high performance liquid chromatography; IL-2, interleukin-2; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylt
The Chemokine Receptor CXCR3 is an Independent Prognostic Factor in Patients With Localized Clear Cell Renal Cell Carcinoma
Keywords: IL-2، اینترلوکین-2; kidney; carcinoma, renal cell; mortality; CXC chemokine receptor 3; neoplasm recurrence, localCAIX, carbonic anhydrase IX; ECOG PS, Eastern Cooperative Oncology Group performance status; IL-2, interleukin-2; RCC, renal cell carcinoma; Th1, T helper type 1
Rapid histone deacetylation and transient HDAC association in the IL-2 promoter region of TSST-1-stimulated T cells
Keywords: IL-2، اینترلوکین-2; IL-2, interleukin-2; TSST-1, toxic shock syndrome toxin-1; OVA, ovalbumin; MHC, major histocompatibility complex; ChIP assay, chromatin immunoprecipitation assay; AcH3, acetylated histone H3; HDAC, histone deacetylase; TCR, T cell receptor; APC, antigen p
Seselin from Plumbago zeylanica inhibits phytohemagglutinin (PHA)-stimulated cell proliferation in human peripheral blood mononuclear cells
Keywords: IL-2، اینترلوکین-2; PBMC, peripheral blood mononuclear cells; IL-2, interleukin-2; IFN-γ, interferon-γ; PHA, phytohemagglutinin; EtOAc, ethyl acetate; TLC, thin-layer chromatography; NMR, nuclear magnetic resonance; DMSO, dimethylsulfoxide; HBSS, Hanks’ buffer saline solutio
Potential role of phospholipase D2 in increasing interleukin-2 production by T-lymphocytes through activation of mitogen-activated protein kinases ERK1/ERK2
Keywords: IL-2، اینترلوکین-2; PLD2, phospholipase D2; PA, phosphatidic acid; DAG, diacylglycerol; PC, phosphatidylcholine; TCR, T-cell receptor; IL-2, interleukin-2; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; LFA-1, lymphocyte function-associat
Regulatory mechanisms of IL-2 and IFNγ suppression by quercetin in T helper cells
Keywords: IL-2، اینترلوکین-2; Th cells, T helper cells; T-bet, T-box protein expressed in T cells; IL-2, interleukin-2; IL-2R, interleukin-2 receptor; IFN, interferonQuercetin; IL-2; IFNγ; Th1; T-bet
The profile of immune modulation by cannabidiol (CBD) involves deregulation of nuclear factor of activated T cells (NFAT)
Keywords: IL-2، اینترلوکین-2; AFC, antibody-forming cell; CBD, cannabidiol; THC, delta-9-tetrahydrocannabinol; IL-2, interleukin-2; IFN-γ, interferon-gammaCannabinoid; Interleukin-2; Interferon-gamma; NFAT; AP-1
Comparative methodologies of regulatory T cell depletion in a murine melanoma model
Keywords: IL-2، اینترلوکین-2; Treg, regulatory T cell; CY, cyclophosphamide; DD, denileukin diftitox; IL-2, interleukin-2; DC, dendritic cell.Regulatory T cell; Dendritic cell; Melanoma; Cyclophosphamide; Denileukin diftitox; Anti-CD25 antibody
The complex role of iNOS in acutely rejecting cardiac transplants
Keywords: IL-2، اینترلوکین-2; cNOS, constitutive nitric oxide synthase; EPR, electron paramagnetic resonance; iNOS, inducible nitric oxide synthase; IFN-γ, interferon-γ; IL-2, interleukin-2; ISHLT, International Society of Heart and Lung Transplantation; L-NIL, N6-(1-iminoethyl)-l-lys
Zinc up-regulates NF-κB activation via phosphorylation of IκB in HUT-78 (Th0) cells
Keywords: IL-2، اینترلوکین-2; NF-κB, nuclear factor of κB; IκB, inhibitory protein of NF-κB; IKK, IκB kinase; IL-2, interleukin-2; IL-2Rα, interleukin-2 receptor-α; PMA, phorbol-12 myristate 13 acetate; PHA, phytohemagglutinin-pZinc; NF-κB; IκB; IL-2; IL-2Rα
Immunotherapy for Orthotopic Murine Bladder Cancer Using Bacillus Calmette-Guerin Recombinant Protein Mpt-64
Keywords: IL-2، اینترلوکین-2; bladder; bladder neoplasms; Mycobacterium bovis; recombinant proteins; miceBCG, bacillus Calmette-Guerin; IFN-γ, interferon-γ; IL-2, interleukin-2; KLH, keyhole limpet hemocyanin; PBS, phosphate buffered saline; Th1, T-helper type 1