دانلود مقالات ISI درباره IN، انتگرال + ترجمه فارسی

Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors

Keywords: IN، انتگرال; Antiviral agents; HIV-1 integrase inhibitors; HIV-1 RNase H inhibitors; Metal complexes; Dual inhibitorsHIV, human immunodeficiency virus; IN, integrase; HAART, highly active antiretroviral therapy; 3-P, 3′-processing; ST, strand-transfer; DKA, diketoacid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Specific features of HIV-1 integrase inhibition by bisphosphonate derivatives

Keywords: IN، انتگرال; HIV; Integrase; Bisphosphonates; Inhibitors; SARHAART, highly active antiretroviral therapy; IN, integrase; BP, bisphosphonate; INSTI, integrase strand transfer inhibitor; LEDGF, lens epithelium derived growth factor; RT, reverse transcriptase; VDPA, viny

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

A comparative study of backbone versus side chain peptide cyclization: Application for HIV-1 integrase inhibitors

Keywords: IN، انتگرال; AIDS, acquired immunodeficiency syndrome; HIV, human immunodeficiency virus; IN, integrase; MAGI, multinuclear activation of a galactosidase indicator; MOI, multiplicity of infection; LEDGF, lens epithelium-derived growth factor; TDW, triple distilled wat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Aspects of HIV-1 assembly that promote primer tRNALys3 annealing to viral RNA

Keywords: IN، انتگرال; HIV-1, human immunodeficiency virus type 1; MA, matrix protein; CA, capsid protein; NC, nucleocapsid protein; PR, protease; RT or, reverse transcriptase; IN, integrase; PBS, primer binding site; MuLV, murine leukemia virus; AMV, avian myeloblastosis virus

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

MuLV IN mutants responsive to HDAC inhibitors enhance transcription from unintegrated retroviral DNA

Keywords: IN، انتگرال; IN, Integrase; M-MuLV, Moloney murine leukemia virus; PIC, pre-integration complex; TSA, Trichostatin A; HDAC, histone deacetylaseNon-integrating vectors; Integrase; MuLV IN; HDAC inhibitors; Pre-integration complex, PIC; Intasome

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus

Keywords: IN، انتگرال; HIV, human immunodeficiency virus; IN, integrase; HCV, hepatitis C virus; SOC, standard of care; peg-INF, peglylated interferon; RBV, ribavirin; SVR, sustained virological response; DAA, direct-acting antiviral; NNI, non-nucleoside inhibitor; EVG, elviteg

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4

Keywords: IN، انتگرال; 2-Hydroxyisoquinoline-1,3(2H,4H)-dione; Integrase; Ribonuclease H; Magnesium complexation; AntiretroviralHAART, highly active antiretroviral therapies; HIV-1, human immunodeficiency virus type 1; IN, integrase; LDA, lithium diisopropylamide; LEDGF, lens e

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

HIV-1 Integrase Strand Transfer Inhibitors Stabilize an Integrase–Single Blunt-Ended DNA Complex

Keywords: IN، انتگرال; IN, integrase; STI, strand transfer inhibitors; ISD, IN–single DNA; RAL, raltegravir; HIV, human immunodeficiency virus; PIC, preintegration complex; LTR, long terminal repeat; SC, synaptic complex; STC, strand transfer complex; PFV, prototype foamy virus

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of Critical Motifs within HIV-1 Integrase Required for Importin α3 Interaction and Viral cDNA Nuclear Import

Keywords: IN، انتگرال; HIV-1, human immunodeficiency virus type 1; PIC, pre-integration complex; Vpr, viral protein R; MA, matrix; IN, integrase; CCD, catalytic core domain; CTD, C-terminal domain; NLS, nuclear localization signal; LTR, long terminal repeat; Co-IP, co-immunopre

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

In Vitro DNA Tethering of HIV-1 Integrase by the Transcriptional Coactivator LEDGF/p75

Keywords: IN، انتگرال; IN, integrase; NLS, nuclear localization signal; LTR, long terminal repeat; PIC, preintegration complex; IBD, integrase binding domain; HIV-1, human immunodeficiency virus type 1; 1O2, singlet oxygen; CR1, charged region 1; MBP, maltose binding protein; F

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2011 سفارش ترجمه

Mechanism of action of the HIV-1 integrase inhibitory peptide LEDGF 361–370

Keywords: IN، انتگرال; AIDS, acquired immunodeficiency syndrome; AA, amino acids; HIV, human immunodeficiency virus; LTR, long terminal repeat; IN, integrase; MAGI, multinuclear activation of a galactosidase indicator; LEDGF, lens epithelium derived growth factor; IBD, integras

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Formation of the tRNALys packaging complex in HIV-1

Keywords: IN، انتگرال; HIV-1, human immunodeficiency virus type 1; MA, matrix protein; CA, capsid protein; NC, nucleocapsid protein; PR, protease; RT, reverse transcriptase; IN, integrase; PBS, primer binding site; MuLV, murine leukemia virus; AMV, avian myeloblastosis virus; a

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Pharmacophore and structure–activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase

Keywords: IN، انتگرال; HIV, human immunodeficiency virus; AIDS, acquired immunodeficiency syndrome; RT, reverse transcriptase; IN, integrase; HEPT, 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine; NNRTI, non-nucleoside reverse transcriptase inhibitors; SAR, structure–activity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Influence of Mg2+ on the binding modes of HIV-1 integrase with thiazolothiazepine inhibitor studied by molecular simulation

Keywords: IN، انتگرال; IN, integrase; THI, thiazolothiazepines; MD, molecular dynamics; RMSD, root mean square deviation.HIV-1 integrase; Thiazolothiazepines; Mg2+ ions; Molecular simulation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Structural analysis of 83-kb genomic DNA from Thellungiella halophila: Sequence features and microcolinearity between salt cress and Arabidopsis thaliana

Keywords: IN، انتگرال; BAC, Bacterial artificial chromosome; dK, The distance estimated by Kimura two-parameter method; DT, Divergence time; IP, Identity percent; IN, Integrase; LTR, Long terminal repeat; MS, Microsatellites; PPT, Polypurine tract; PR, Protease; PBS, Primer-bin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Defining the DNA Substrate Binding Sites on HIV-1 Integrase

Keywords: IN، انتگرال; HIV-1, human immunodeficiency virus type 1; IN, integrase; LTR, long terminal repeat; SIV, simian immunodeficiency virus; ASV, avian sarcoma virus; LEDGF, lens-epithelium-derived growth factor; MLV, murine leukemia virus; oligo, oligodeoxyribonucleotideHI

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and anti-HIV-1 integrase activity of modified dinucleotides

Keywords: IN، انتگرال; HIV-1 integrase inhibitors; Modified dinucleotides; Intercalator-dinucleotide conjugatesHIV-1, Human Immunodeficiency virus type 1; IN, Integrase; DNA, Deoxyribonucleic Acid; FDA, Food and Drug Administration; IC 50, half maximal inhibitory concentration

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

Keywords: IN، انتگرال; HIV-1, human immunodeficiency virus type 1; RT, reverse transcriptase; PR, protease; IN, integrase; PBS, primer binding site; R, repeat; PPT, polypurine tract; LTR, long terminal repeat; DEC, dead-end complex; NRTI, nucleoside RT inhibitor; NNRTI, nonnucl

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase–DNA complex formation and catalysis

Keywords: IN، انتگرال; HIV-1, human immunodeficiency virus type 1; IN, integrase; WT, wild-type; LEDGF, lens epithelium-derived growth factor; IBD, integrase binding domainHIV-1; Integrase; Cellular cofactor; LEDGF/p75; Peptide; Peptidomimetic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity

Keywords: IN، انتگرال; HIV-1, human immunodeficiency virus type 1; IN, integrase; WT, wild type; SM, soluble double mutant (F185K/C280S) integrase proteinHIV-1; Integrase; 3′-Processing; Strand transfer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Single-particle Image Reconstruction of a Tetramer of HIV Integrase Bound to DNA

Keywords: IN، انتگرال; IN, integrase; BME, β-mercaptoethanolHIV; integrase; DNA-binding; electron microscopy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Ogre elements — A distinct group of plant Ty3/gypsy-like retrotransposons

Keywords: IN، انتگرال; EST, expressed sequence tag; IN, integrase; LTR, long terminal repeat; ORF, open reading frame; PBS, primer binding site; PPT, polypurine tract; RH, RNaseH; RT, reverse transcriptase.Transposable elements; LTR retrotransposons; Computational identificatio

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of the LEDGF/p75 Binding Site in HIV-1 Integrase

Keywords: IN، انتگرال; LEDGF, lens epithelium-derived growth factor; HIV, human immunodeficiency virus; IN, integrase; IBD, integrase binding domain; PIC, pre-integration complex; Y2H, yeast two-hybrid; ELISA, enzyme-linked immunosorbent assay; RT, reverse transcriptase; NLS, n

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of the Activities of Reverse Transcriptase and Integrase of Human Immunodeficiency Virus Type-1 by Peptides Derived from the Homologous Viral Protein R (Vpr)

Keywords: IN، انتگرال; HIV, human immunodeficiency virus; PIC, preintegration complex; RT, reverse transcriptase; IN, integrase; Vpr, viral protein R; CCD, catalytic core domain; AIDS, acquired immune deficiency syndrome; PDB, Protein Data BankHIV-1; reverse transcriptase; inte

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Differential Interaction of HIV-1 Integrase and JPO2 with the C Terminus of LEDGF/p75

Keywords: IN، انتگرال; LEDGF, lens epithelium-derived growth factor; STRE, stress responsive; HSE, heat shock element; HIV-1, human immunodeficiency virus type 1; HDGF, hepatoma-derived growth factor; IN, integrase; IBD, integrase-binding domain; MAO, monoamine oxidase; SID, sp

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه