دانلود مقالات ISI درباره همبستگی in vitro-in vivo + ترجمه فارسی

مدل سازی فارماکوکینتیک جمعیت ترامادول با استفاده از تابع گاو معکوس برای ارزیابی جذب دارو از فرمولاسیون های طولانی و فوری

Population pharmacokinetic modelling of tramadol using inverse Gaussian function for the assessment of drug absorption from prolonged and immediate release formulations

Keywords: همبستگی in vitro-in vivo; AIC; Akaike information criteria; BCS; Biopharmaceutics Classification System; BLQ; below the limit of quantification; CI; confidence interval; CYP2D6; cytochrome P450 2D6; GC-MS; gas chromatography coupled to mass spectrometry; IIV; interindividual var

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Systematically optimized topical delivery system for Loperamide hydrochloride: Formulation design, in vitro and in vivo biopharmaceutical evaluation

Keywords: همبستگی in vitro-in vivo; Loperamide hydrochloride; Topical delivery; Skin retention; In vitro-in vivo correlation;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation

Keywords: همبستگی in vitro-in vivo; MARK; Kinase; Pharmacokinetics; Optimization; Physical properties; Disposition study; In vitro-in vivo correlation;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Sex-by-formulation interaction assessed through a bioequivalence study of efavirenz tablets

Keywords: همبستگی in vitro-in vivo; Sex-by-formulation interaction; Bioequivalence; In vitro-in vivo correlation; Efavirenz;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Enhanced oral bioavailability of capsaicin in mixed polymeric micelles: Preparation, in vitro and in vivo evaluation

Keywords: همبستگی in vitro-in vivo; PVP; polyvinylpyrrolidone;; IVIVC; in vitro-in vivo correlation;; TEM; transmission electron microscopy;; EE; encapsulation efficiency;; CMC−Na; sodium carboxymethylcellulose;; MRT; mean residence time;; DLS; dynamic light scattering; Capsaicin; Micel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Paclitaxel-loaded polymeric microparticles: Quantitative relationships between in vitro drug release rate and in vivo pharmacodynamics

Keywords: همبستگی in vitro-in vivo; AIC; Akaike Information Criterion; GA; glycolic acid; HPLC; high performance liquid chromatograph; ILS; increase in life span; IP; intraperitoneal; LA; lactic acid; MST; median survival time; PLGA; poly(d,l-lactide-co-glycolide) acid; Tg; glass transition

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Prediction of Total Hepatic Clearance by Combining Metabolism, Transport, and Permeability Data in the In Vitro-In Vivo Extrapolation Methods: Emphasis on an Apparent Fraction Unbound in Liver for Drugs

Keywords: همبستگی in vitro-in vivo; hepatocytes; intrinsic clearance; unbound fraction; metabolism; transport; permeability; in vitro-in vivo extrapolation; in vitro-in vivo correlation; IVIVE; pharmacokinetics; physiologically based pharmacokinetics; PBPK modeling;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Osmotic Release of Bioactive VEGF from Biodegradable Elastomer Monoliths is the Same In Vivo As In Vitro

Keywords: همبستگی in vitro-in vivo; vascular endothelial growth factor; in vitro-in vivo correlation; osmotic pressure release; degradable elastomer; angiogenesis; protein delivery; biodegradable polymer; osmosis; controlled release;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of Drug Supersaturation by Thermodynamic and Kinetic Approaches for the Prediction of Oral Absorbability in Amorphous Pharmaceuticals

Keywords: همبستگی in vitro-in vivo; supersaturation; amorphous; crystallization; thermodynamics; kinetics; oral absorption; in vitro-in vivo correlation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Comparative Assessment of In Vitro-In Vivo Extrapolation Methods used for Predicting Hepatic Metabolic Clearance of Drugs

Keywords: همبستگی in vitro-in vivo; disposition; microsomes; clearance; unbound fraction; computational ADME; in vitro-in vivo extrapolation; in vitro-in vivo correlation; IVIVE; pharmacokinetics; PBPK modeling;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

In vitro-in vivo correlation and bioavailability studies of captopril from novel controlled release donut shaped tablet

Keywords: همبستگی in vitro-in vivo; Donut; Coated; Captopril; In vitro; In vivo; In vitro-in vivo correlation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration-time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Keywords: همبستگی in vitro-in vivo; animal alternative; computational ADME; drug discovery; drug development; absorption; distribution; disposition; in vitro-in vivo correlation; pharmacokinetics; PBPK modeling;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2011 سفارش ترجمه

A comparison of the effects of p-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE)

Keywords: همبستگی in vitro-in vivo; blood-brain barrier; brain perfusion; cell culture; in vitro; in vitro-in vivo correlation; MDCK-WT cells; MDCK-MDR1 cells; P-glycoprotein; quinidine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Correlation between in vitro dissolution profiles from enteric-coated dosage forms and in vivo absorption in rats for high-solubility and high-permeability model drugs

Keywords: همبستگی in vitro-in vivo; in vitro-in vivo correlation; IVIVC; in vitro dissolution; in vivo absorption; enteric-coated dosage form; hypromellose acetate succinate;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Ketotifen-Loaded Microspheres Prepared by Spray-Drying Poly (D,L-Lactide) and Poly(D,L-Lactide-co-Glycolide) Polymers: Characterization and In Vivo Evaluation

Keywords: همبستگی in vitro-in vivo; ketotifen; poly(D,L-lactide); poly(D,L-lactide-co-glycolide); microspheres; spray-drying; in vitro-in vivo correlation;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

IV-IVC for topically applied preparations-a critical evaluation

Keywords: همبستگی in vitro-in vivo; In vitro-in vivo correlation; In vitro release; Rheological properties; Spreadability; Dermatopharmacokinetics; DPK; Pharmacodynamics;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Drug permeability in 16HBE14o- airway cell layers correlates with absorption from the isolated perfused rat lung

Keywords: همبستگی in vitro-in vivo; 16HBE14o-; Epithelium; Caco-2; Pulmonary absorption; In vitro-in vivo correlation; Rat;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Multivesicular liposome formulation for the sustained delivery of breviscapine

Keywords: همبستگی in vitro-in vivo; Breviscapine; Multivesicular liposomes; Sustained delivery; In vitro-in vivo correlation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

The Study of In Vitro-In Vivo Correlation: Pharmacokinetics and Pharmacodynamics of Albuterol Dry Powder Inhalers

Keywords: همبستگی in vitro-in vivo; albuterol; aerosol; in vitro-in vivo correlation; pharmacodynamics; pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه