JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-κB activation and the JAK/STAT pathway
Keywords: JANEX-1, 4-(4′-hydroxyphenyl)-amino-6,7-dimethoxyquiazoline; IL-1β, interleukin-1β; IFN-γ, interferon-γ; NO, nitric oxide; iNOS, inducible form of nitric oxide synthase; NF-κB, nuclear factor κB; IκB, inhibitory factor of NF-κB; JAK, Janus kinase; STAT, s