
Modifying the determinants of α-ketoacid substrate selectivity in mycobacterium tuberculosis α-isopropylmalate synthase
Keywords: AcCoA; acetyl coenzyme A; HCS; homocitrate synthase; IPMS; α-isopropylmalate synthase; IPTG; isopropyl thio-d-galactoside; KIV; α-ketoisovalerate; PDB; protein data bank; MtuIPMS; Mycobacterium tuberculosis IPMS; TthHCS; Thermus thermophilus HCS; Leucin