دانلود مقالات ISI درباره IR، تابش یونیزه + ترجمه فارسی

Higher-order chromatin structure in DSB induction, repair and misrepair

Keywords: IR، تابش یونیزه; DSB, DNA double-strand break; γH2AX, histone H2AX phosphorylated on serine 139; PFGE, pulse-field gel electrophoreses; PI, post-irradiation; IR, ionizing radiation; IRIF, ionizing radiation-induced foci; RIDGE, regions of increased gene expression; antiRI

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Radioprotection by short-term oxidative preconditioning: Role of manganese superoxide dismutase

Keywords: IR، تابش یونیزه; H2O2, hydrogen peroxide; PI, propidium iodide; PS, phosphatidylserine; AA, antimycin A; MnSOD, manganese superoxide dismutase; IR, ionizing radiation; MECs, mouse embryonic cells; SC, scrambled controlApoptosis; MnSOD; Irradiation; Preconditioning; ROS

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Pyridoxamine protects intestinal epithelium from ionizing radiation-induced apoptosis

Keywords: IR، تابش یونیزه; BSA, bovine serum albumin; GI, gastrointestinal; IR, ionizing radiation; PBS, phosphate-buffered saline; PM, pyridoxamine; ROS, reactive oxygen species; RCS, reactive carbonyl species.Ionizing radiation; Radioprotection; Reactive oxygen species; Reactive

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

In vitro non-homologous DNA end joining assays—The 20th anniversary

Keywords: IR، تابش یونیزه; AFIGE, asymmetric field inversion gel electrophoresis; APE1, apurinic/apyrimidinic endonuclease; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; DSBs, DNA double-strand breaks; IR, ionizing radiation; NHEJ, non-homologous DNA end joining; PNK, p

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Choreography of recombination proteins during the DNA damage response

Keywords: IR، تابش یونیزه; DSB, double-strand break; DSBR, double-strand break repair; HR, homologous recombination; IR, ionizing radiation; MMS, methyl methanesulfonate; NHEJ, non-homologous end-joining; RPA, replication protein A; GFP, green fluorescent protein; CFP, cyan fluores

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of rDNA stability by sumoylation

Keywords: IR، تابش یونیزه; 4-NQO, 4-nitroquinoline 1-oxide; BIR, break-induced repair; DSB, double-strand break; GC, gene conversion; HR, homologous recombination; IR, ionizing radiation; MMS, methyl methanesulfonate; NHEJ, non-homologous end-joining; rDNA, ribosomal DNA; RFB, repl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation

Keywords: IR، تابش یونیزه; Apex1, apurinic/apyrimidinic endonuclease 1; DSB, double-strand break; HRR, homologous recombination repair; IR, ionizing radiation; MEFs, mouse embryonic fibroblasts; NHEJ, non-homologous end-joining; PG, phosphoglycolate; pTyr, phosphotyrosyl; Pnkp, pol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia–telangiectasia cells

Keywords: IR، تابش یونیزه; A-T, ataxia–telangiectasia; WT, wild type; SOD, superoxide dismutase; IR, ionizing radiation; DSB, double-strand break; IRIF, irradiation-induced immunofluorescent nuclear focus; MnTM-2-PyP5+, manganese(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)por

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Serum starvation induces H2AX phosphorylation to regulate apoptosis via p38 MAPK pathway

Keywords: IR، تابش یونیزه; IR, ionizing radiation; UV, ultraviolet; MEFs, mouse embryonic fibroblasts; MAPKs, mitogen-activated protein kinases; TBST, Tris-buffered saline containing Tween 20H2AX; Apoptosis; p38; MAPK

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations

Keywords: IR، تابش یونیزه; Aprt, adenine phosphoribosyltransferase; DSB, double-strand break; Hprt, hypoxanthineguanine phosphoribosyltransferase; IR, ionizing radiation; MF, mutant frequency; MMR, mismatch repair; MR, mitotic recombinationLoss of heterozygosity; Mismatch repair; M

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Low doses of alpha particles do not induce sister chromatid exchanges in bystander Chinese hamster cells defective in homologous recombination

Keywords: IR، تابش یونیزه; CHO, Chinese hamster ovary; DSB, double-strand break; GJIC, gap-junction-mediated intercellular communication; HPRT, hypoxanthine-guanine phosphoribosyltransferase; HRR, homologous recombinational repair; IR, ionizing radiation; NHEJ, non-homologous end j

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Amplification of the γ-irradiation-induced cell death pathway by reactive oxygen species in human U937 cells

Keywords: IR، تابش یونیزه; JNK, c-Jun N-terminal kinase; ROS, reactive oxygen species; IR, ionizing radiation; siRNA, small interfering RNA; DCF, 2′,7′-dichlorofluorescein; ΔΨm, mitochondrial transmembrane potential; MPT, mitochondrial permeability transition; CsA, cyclosporine A.C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Two distinctly altered cellular responses to DNA double-strand breaks in human neuroblastoma

Keywords: IR، تابش یونیزه; Neuroblastoma; DNA double-strand breaks; Chk2; p21; VimentinNB, neuroblastoma; MNA, MYCN amplification; DSB, double-strand break; ATM, ataxia telangiectasia mutated; NSE, neuron-specific enolase; NCS, neocarzinostatin; IR, ionizing radiation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H2O2

Keywords: IR، تابش یونیزه; GBM, glioblastoma multiforme; IR, ionizing radiation; ROS, reactive oxygen species; SOD, superoxide dismutase; GSH, reduced glutathione; GSSG, oxidized glutathione; GPx, glutathione peroxidase; GR, glutathione reductase; DMEM, Dulbecco’s minimum essential

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

NF-κB-mediated adaptive resistance to ionizing radiation

Keywords: IR، تابش یونیزه; ATM, ataxia-telangiectasia mutated; ERK, extracellular signal-regulated kinase; FIR, fractionated ionizing radiation; GADD45β, growth arrest DNA damage gene 45β; IκB, inhibitor-κB; IKK, IκB kinase; IL-1, interleukin-1; IR, ionizing radiation; JNK, c-Jun N

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1

Keywords: IR، تابش یونیزه; DNA damage; ICRF-193; Topoisomerase II; Cell cycle; G2 arrestA-T, ataxia-telangiectasia; ATM, ataxia-telangiectasia mutated; ATR, ATM- and Rad3-related; DSB, DNA double-strand breaks; IR, ionizing radiation; ATR-kd, kinase-dead ATR; LMP, low melting point

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

p53 translational control: A new facet of p53 regulation and its implication for tumorigenesis and cancer therapeutics

Keywords: IR، تابش یونیزه; IRES, internal ribosome entry site; IR, ionizing radiation; UVC, short ultraviolet; UTR, untranslated region; RT-PCR, reverse transcriptase PCR; ELAV, embryonic lethal abnormal vision; 4E-BP1, eIF4E binding protein 1; hnRNP, heterogeneous ribonuclear part

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit DNA-repair defects post exposure to gamma ionizing radiation

Keywords: IR، تابش یونیزه; HAT, histone acetyltransferase; HDAC, histone deacetylase; IR, ionizing radiation; MEFs, mouse embryonic fibroblasts; MORF4, mortality factor on chromosome 4; MRG15, MORF4-related gene on chromosome 15; TSA, trichostatin A; het, heterozygousMORF4; NuA4; S

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells

Keywords: IR، تابش یونیزه; ANOVA, One-way analysis of variance; asHTF, Alternative splice variant of human TF; AU, Arbitrary units; DIC, Disseminated intravascular coagulation; FCS, Fetal Calf Serum; ICBT, Intracoronary brachytherapy; IR, Ionizing radiation; LPS, Lipopolysaccharide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Analysis of DNA repair and recombination responses in mouse cells depleted for Brca2 by SiRNA

Keywords: IR، تابش یونیزه; IR, ionizing radiation; MMC, mitomycin C; MMS, methyl methane sulfonate; SiRNA, small inhibitory RNA; TNP, 2,4,6-trinitrophenyl; TNP-specific PFC, TNP-specific plaque forming cellsMouse hybridoma cells; Small inhibitory RNA; Brca2; DNA damaging agents; DN

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Characterization of the porcine ATM gene: Towards the generation of a novel non-murine animal model for Ataxia-Telangiectasia

Keywords: IR، تابش یونیزه; aa, amino acid(s); AS, alternative splicing; ATM, Ataxia-Telangiectasia mutated: BAC, bacterial artificial chromosome; bp, base pair; cDNA, complementary to RNA; IR, ionizing radiation; kb, kilobase pair or 1000 bp; nt, nucleotide; ORF, open reading frame

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Ionizing radiation induces a Yap1-dependent peroxide stress response in yeast

Keywords: IR، تابش یونیزه; IR, ionizing radiation; SSB, single-strand break; DSB, double-strand break; GPx, glutathione peroxidase; 2D-PAGE, two-dimensional polyacrylamide gel electrophoresis; ORF, open-reading frame; SD, synthetic defined minimal medium; YPD, yeast peptone dextros

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model

Keywords: IR، تابش یونیزه; IR, ionizing radiation; qPCR, quantitative polymerase chain reaction; MEF, mouse embryo fibroblast; NMD, nonsense-mediated RNA decayCHEK2; Breast cancer; DNA damage; Mouse model; Genomic instability

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway

Keywords: IR، تابش یونیزه; IR, ionizing radiation; AP, apurinic/apyrimidinic site; αdN, alpha-anomeric 2′-deoxynucleosides; αdC, alpha-anomeric 2′-deoxycytidine; 5ohC, 5-hydroxycytosine; DHU, 5,6-dihydrouracil; 5ohU, 5-hydroxyuracil; THF, tetrahydrofuran; 8oxoG, 7,8-dihydro-8-oxogu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Role for DNA polymerase beta in response to ionizing radiation

Keywords: IR، تابش یونیزه; APE1, AP endonuclease 1; BER, base excision repair; dRP, 5′ deoxyribose phosphate; DSB, double strand break; DSBR, double strand break repair; FEN1, flap endonuclease 1; H2O2, hydrogen peroxide; IR, ionizing radiation; J, Joule; LI, labeling index; MEF, m

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress

Keywords: IR، تابش یونیزه; RNR, ribonucleotide reductase; ATM, ataxia telangiectasia-mutated; ATR, ATM and Rad3-related; DSBs, DNA double-stranded breaks; IR, ionizing radiation; chk1, checkpoint kinase 1; γ-H2Ax, phosphorylated-histone 2Ax; sh/siRNA, short hairpin/short interferen

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of sequences that target BRCA1 to nuclear foci following alkylative DNA damage

Keywords: IR، تابش یونیزه; ATM, ataxia telangiectasia mutated; ATR, ATM and Rad3 related; DMEM, Dulbecco's modified Eagle's medium; DSB, double-strand break; IR, ionizing radiation; EMS, ethyl methanesulfonate; MMTS, methyl methanethiosulfonate; MMS, methyl methanesulfonate; PBS, p

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Ionizing radiation suppresses FAP-1 mRNA level in A549 cells via p53 activation

Keywords: IR، تابش یونیزه; FAP-1, Fas-associated phosphatase-1; FITC, fluorescein isothiocyanate; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IR, ionizing radiation; MFI, mean fluorescence intensity; PFTα, pifithrin αFas; Fas-associated phosphatase-1; Ionizing radiation; p53

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

The Fanconi anemia pathway limits the severity of mutagenesis

Keywords: IR، تابش یونیزه; CHO, chinese hamster ovary; DSB, double-strand break; FA, Fanconi anemia; Hprt, hypoxanthine phosphoribosyltransferase; HRR, homologous recombination repair; IR, ionizing radiation; NHEJ, nonhomologous end joining; 6S-Gua, 6-thioguanineSpontaneous mutatio

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Microarray analysis of differentially expressed genes after exposure of normal human fibroblasts to ionizing radiation from an external source and from DNA-incorporated iodine-125 radionuclide

Keywords: IR، تابش یونیزه; IR, ionizing radiation; HDR, high-dose rate; LDR, low-dose rate; DSB, double-strand break; 125I-IUdR, [125I]-iododeoxyuridine; LET, linear energy transfer; cDNA, DNA complementary to RNA; PBS, phosphate-buffered saline; EMEM, Eagle's Minimum Essential Med

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage

Keywords: IR، تابش یونیزه; Plk3, polo-like kinase 3; ATM, ataxia-telangiectasia mutated; IR, ionizing radiation; FPLC, fast performance liquid chromatography; GFP, green fluorescence proteinPlk3; Chk2; ATM; DNA damage; Priming phosphorylation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Possible genetic damage in the Czech nuclear power plant workers

Keywords: IR، تابش یونیزه; AB.C., aberrant cells; FISH, fluorescence in situ hybridization; IR, ionizing radiation; mSv, miliSievert, unit of the radiation equivalent dose; NPP, nuclear power plant; PAINT, protocol for aberrations identification and nomenclature; PBL, peripheral bl

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells

Keywords: IR، تابش یونیزه; ATM, ataxia telangiectasia mutated kinase; CHO, Chinese hamster ovary; DAPI, 4,6-diamidino-2-phenylindole; DNA-PK, DNA-dependent protein kinase; DSB, DNA double-strand break; HSF, human skin fibroblast; IR, ionizing radiation; PCD, programmed cell death;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Control of p53 nuclear accumulation in stressed cells

Keywords: IR، تابش یونیزه; MDM, murine double minute; NLS, nuclear localization signal; NES, nuclear export signal; IR, ionizing radiation; Etop., etoposide; Act. D, actinomycin D; LMB, leptomycin B; HA, hemagglutinin; GFP, green fluorescent protein; OD, oligomerization domain; p53

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه