دانلود مقالات ISI درباره استاندارد داخلی + ترجمه فارسی

محتوای فیبر رژیم غذایی ناشی از تنش های ناشی از انقباض در حالت ناشتا و پس از ریزش در یک مطالعه متقاطع آزمایشی

Fiber content of diet affects exhaled breath volatiles in fasting and postprandial state in a pilot crossover study

Keywords: استاندارد داخلی; Exhaled breath; Volatile organic compounds; Dietary fiber; Postprandial test; Randomized crossover trialBCFA, branched-chain fatty acid; DF, dietary fiber; GC-MS, gas chromatography–mass spectrometry; HFD, high-fiber diet; IS, internal standard; LFD, low-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

تعیین همزمان اسید شیکیمیک، اسید سالیسیلیک و اسانس جاسونیک در گیاهان نیکوتینا لنسدورفینی وحشی و ترنسژنیک در معرض تنش های بی رویه

Simultaneous determination of shikimic acid, salicylic acid and jasmonic acid in wild and transgenic Nicotiana langsdorffii plants exposed to abiotic stresses

Keywords: استاندارد داخلی; Abiotic stress; Jasmonic acid; Nicotiana langsdorffii; Rat glucocorticoid receptor gene; rol C; Salicylic acid; Shikimic acidABA, Abscisic acid; ACN, acetonitrile; Cr, chromium; gr, glucocorticoid receptor; HS, heat stress; IS, internal standard; FR, inst

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

تعیین همزمان بوپرنورفین، نوروبپرانورفین و نالوکسون در پلاسمای انسانی با استفاده از کروماتوگرافی مایع / طیف سنجی جرم دو طرفه

Simultaneous determination of buprenorphine, norbuprenorphine and naloxone in human plasma by liquid chromatography/tandem mass spectrometry

Keywords: استاندارد داخلی; BUP, buprenorphine; NAL, naloxone; NorBUP, norbuprenorphine; IS, internal standard; CV, coefficient of variation; AUC0-last, area under the concentration-time curve in plasma from time zero (predose) to the time of last quantifiable concentration; AUC0-in

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

تعیین مشخصات متابولیک ژنتیانین پس از تزریق دهان به موشها با استفاده از کروماتوگرافی مایع با کارایی بالا / طیف سنجی جرمی یونیزاسیون اسپری الکترو اسپری

Determination of the metabolic profile of gentianine after oral administration to rats by high performance liquid chromatography/electrospray ionization-trap mass spectrometry

Keywords: استاندارد داخلی; LC/MS, liquid chromatography–mass spectrometry; ESI, electrospray ionization; IS, internal standard; TIC, total ion currentGentianine; Metabolite; LC–MS

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

تعیین همزمان کپسیباتین و متابولیت های نوکلئیدی آن در پلاسمای انسان با استفاده از کروماتوگرافی مایع با عملکرد بالا طیف سنجی جرمی

Simultaneous determination of capecitabine and its three nucleoside metabolites in human plasma by high performance liquid chromatography–tandem mass spectrometry

Keywords: استاندارد داخلی; 5-FU, 5-fluorouracil; Cape, capecitabine; DFCR, 5′-deoxy-5-fluorocytidine; DFUR, 5′-deoxy-5-fluorouridine; EMA, European Medicines Agency; FDA, Food and Drug Administration; HQC, high quality control; IS, internal standard; LLOQ, lower limit of quantifica

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

پاکسازی نمونه ساده با استفاده از استخراج جامد فاز جامد و فیلتراسیون درونی برای تجزیه و تحلیل آفت کش ها و آلاینده های محیطی در میگو آ

Streamlined sample cleanup using combined dispersive solid-phase extraction and in-vial filtration for analysis of pesticides and environmental pollutants in shrimp

Keywords: استاندارد داخلی; DPX, Disposable pipette extraction; d-SPE, Dispersive solid-phase extraction; FRs, Flame retardants; HPLC-MS/MS, High-performance liquid chromatography – tandem mass spectrometry; IS, Internal standard; LOD, Limit of detection; LOQ, Limit of quantificatio

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

تست چند ماتریسی اولین آگوملاتین ضد افسردگی ملاتونرژیک با تشخیص کروماتوگرافی مایع همراه با فلوریمتریک و میکروکاکساسیون با استفاده از جاذب بسته بندی شده

Multi-matrix assay of the first melatonergic antidepressant agomelatine by combined liquid chromatography-fluorimetric detection and microextraction by packed sorbent

Keywords: استاندارد داخلی; MDD, Major Depressive Disorder; AGO, agomelatine; MLT, melatonin; IS, internal standard; DBS, dried blood spot; MEPS, microextraction by packed sorbent; MAE, microwave assisted extraction; SPE, solid phase extraction; LLE, liquid–liquid extraction; TDM, t

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

دفع متابولیت های تکرتیرین در ادرار و صفراوی موش صحرایی در دوزهای مختلف و فعالیت مهار کننده آنها علیه آلدواز ردوکتاز

Excretion of tectoridin metabolites in rat urine and bile orally administrated at different dosages and their inhibitory activity against aldose reductase

Keywords: استاندارد داخلی; AR, aldose reductase; Dihydro-Te, dihydrotectorigenin; EIC, extracted ion chromatograms; HE, high energy; IR, infrared radiation; Ir-7G, irisolidone-7-O-glucuronide; IS, internal standard; Iso-Te, isotectorigenin; LE, low energy; LLOQ, lower limit of quan

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

محاسبه مقدار نورووتوکسین آنوناسین محیطی در مغز موش توسط UPLC-MS / MS

Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS

Keywords: استاندارد داخلی; Acetogenin; Annonaceae; Annonacin; Distribution; Rat brain; UPLC-MS/MSAAG, Annonaceous acetogenin; amu, atomic mass unit; CI, confidence interval; EMA, European Medicines Agency; IS, internal standard; i.v., intravenous; LLOQ, lower limit of quantificatio

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

تعیین کمی استرون توسط طیف سنجی جرمی پشت سر هم ـ کروماتوگرافی مایع در بافت چربی زیرجلدی از پستان در زنان یائسه

Quantitative determination of estrone by liquid chromatography–tandem mass spectrometry in subcutaneous adipose tissue from the breast in postmenopausal women

Keywords: استاندارد داخلی; BMI, body mass index; GC–MS, gas chromatography-mass spectrometry; IS, internal standard; LC–MS/MS, liquid chromatography–tandem mass spectrometry; RIA, radioimmunoassay; STS, steroid sulfataseEstrone; Estrogen; Adipose tissue; Menopause; Breast cancer; L

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Validated UHPLC–MS/MS method for the simultaneous determination of pramipexole and ropinirole in plasma of patients with Parkinson’s disease

Keywords: استاندارد داخلی; PRA, pramipexole; ROP, ropinirole; IS, internal standard; DA, dopaminergic agonists; PD, Parkinson’s disease; UHPLC–MS/MS, ultra high performance liquid chromatography-tandem mass spectrometry; LLE, liquid–liquid extraction; TDM, therapeutic drug monitori

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats

Keywords: استاندارد داخلی; ITP, Idiopathic Thrombocytopenic Purpura; CPL, Carica papaya Linn. Leaves; MRM, Multiple Reaction Monitoring; GLP, Good Laboratory Practice; CPCSEA, Committee for the Purpose of Control and Supervision of Experiments on Animals; IS, Internal Standard; LLO

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Simultaneous determination of levophencynonate and its metabolite demethyl levophencynonate in human plasma by liquid chromatography tandem mass spectrometry

Keywords: استاندارد داخلی; HPLC–MS/MS, high performance liquid chromatography tandem mass spectrometry; ESI, electro-spray ionization; LLOQ, lower limit of quantitation; LPH, levophencynonate; DMLPH, demethyl levophencynonate; d3-LPH, d3-levophencynonate; IS, internal standard; QC,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Liquid chromatography–tandem mass spectrometric assay for the T790M mutant EGFR inhibitor osimertinib (AZD9291) in human plasma

Keywords: استاندارد داخلی; TKI, tyrosine kinase inhibitor; EGFR-TK, epidermal growth factor receptor-tyrosine kinase; IS, internal standard; LC–MS/MS, liquid chromatography–tandem mass spectrometry; LLE, liquid–liquid extraction; NSCLC, non-small cell lung carcinoma; PP, protein pr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

LC–MS/MS determination and urinary excretion study of seven alkaloids in healthy Chinese volunteers after oral administration of Shuanghua Baihe tablets

Keywords: استاندارد داخلی; SBT, Shuanghua Baihe tablets; IS, internal standard; LLOQ, lower limit of quantification; LQC, low QC; MQC, medium QC; HQC, high QC; MRM, multiple reaction monitoring; RE, relative errorBerberine; Berberrubine; LC–MS/MS; Magnoflorine; Shuanghua Baihe tabl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

A chiral LC–MS/MS method for the stereospecific determination of efonidipine in human plasma

Keywords: استاندارد داخلی; LLE, liquid-liquid extraction; DHP, dihydropyridine; CKD, chronic kidney disease; BP, blood pressure; MBF, medullary blood flux; IS, internal standard; ESI, electrospray ionization; CAD, collision activated dissociation; EP, entrance potential; CXP, colli

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Determination of tulobuterol in rat plasma using a liquid chromatography–tandem mass spectrometry method and its application to a pharmacokinetic study of tulobuterol patch

Keywords: استاندارد داخلی; LC–MS/MS, liquid chromatography–tandem mass spectrometry; MR, multiple reaction monitoring; IS, internal standard; HPLC, high performance liquid chromatography; ESI, electrospray ionization; LLE, liquid–liquid extraction; LLOQ, lower limit of quantificati

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Development and validation of a UHPLC–MS/MS method for simultaneous quantitation the plasma concentration of Sabarubicin and its alcohol metabolite M3 in Chinese small cell lung cancer patients

Keywords: استاندارد داخلی; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; CFDA, China Food and Drug Administration; UHPLC–MS/MS, ultra high performance liquid chromatography–tandem mass spectrometry; IS, internal standard; HPLC-grade, high performance liquid chrom

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Detection and quantification of the selective EP4 receptor antagonist CJ-023423 (grapiprant) in canine plasma by HPLC with spectrofluorimetric detection

Keywords: استاندارد داخلی; PGE2, prostaglandin E2; IS, internal standard; ACN, acetonitrile; MeOH, methanol; CH2Cl2, dichloromethane; Et2O, diethyl ether; CHCl3, chloroform; C3H8O, 2-propanol; AcOEt, ethyl acetate; AcONH4, ammonium acetate; HCl, hydrochloric acid; NaOH, sodium hydr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Development and validation of an HPLC–MS/MS method to determine clopidogrel in human plasma

Keywords: استاندارد داخلی; ESI, electrospray ionization; IS, internal standard; LC–MS/MS, liquid chromatography tandem mass spectrometry; LLOQ, lower limit of quantification; MRM, multiple reaction monitoring; SPE, solid phase extraction; QC, quality controlClopidogrel; Online-SPE;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Alterations of the exo- and endometabolite profiles in breast cancer cell lines: A mass spectrometry-based metabolomics approach

Keywords: استاندارد داخلی; Metabolomics; Breast cancer; Quadrupole time-of-flight; Liquid chromatography; Mass spectrometryESI, electrospray ionization; IS, internal standard; LC (HPLC), high-performance liquid chromatography; LC-MS, liquid chromatography mass spectrometry; MS, mas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Chemical and biological assessment of Jujube (Ziziphus jujuba)-containing herbal decoctions: Induction of erythropoietin expression in cultures

Keywords: استاندارد داخلی; ASR, Anelicae Sinensis Radix; CC, Cinnamomi Cortex; CR, Cinnamomi Ramulus; EPO, erythropoietin; GRRPM, Glycyrrhizae Radix et Rhizoma Praeparata cum Melle; HIF, hypoxia induced factor; GZT, Guizhi Tang; HRE, hypoxia response element; IS, internal standard;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacokinetic studies of novel berberine derivatives with ultra-performance liquid chromatography–tandem mass spectrometry

Keywords: استاندارد داخلی; BBR, berberine; UPLC–MS/MS, ultra-performance liquid chromatography with tandem mass spectrometric detection; HCPT, 10-hydroxycamptothecin; IS, internal standard; MRM, multiple reaction-monitoring; ESI, electro-spray ionization; LLOQ, lower limit of quant

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Metabolic studies of prostanozol with the uPA-SCID chimeric mouse model and human liver microsomes

Keywords: استاندارد داخلی; AAS, anabolic androgenic steroids; CEVAC, center for vaccinology; EIC, extracted ion chromatogram; GC–MS, gas chromatography–mass spectrometry; HAc, acetic acid; HLM, human liver microsomes; IS, internal standard; LC–MS/MS, liquid chromatography–tandem ma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Stereoselective pharmacokinetic and metabolism studies of 20(S)- and 20(R)-ginsenoside Rg3 epimers in rat plasma by liquid chromatography-electrospray ionization mass spectrometry

Keywords: استاندارد داخلی; AUC, area under the curve; Cmax, peak plasma concentration; ig, intra-gastric; IS, internal standard; iv, intravenous; LC–MS/MS, liquid chromatography coupled with tandem mass spectrometry; LLOQ, lower limit of quantitation; MRM, multiple reaction monitor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

HPLC method development for the online-coupling of chromatographic Perilla frutescens extract separation with xanthine oxidase enzymatic assay

Keywords: استاندارد داخلی; XOD, xanthine oxidase; IS, internal standard; ROS, reactive oxygen species; RC, reaction coilOnline coupled continuous flow system; HPLC method development; Temperature gradient; Xanthine oxidase; Perilla frutescens; Inhibition

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

LC–MS/MS as a tool for TDM services: Where are we?

Keywords: استاندارد داخلی; DBS, dried blood spot samples; ILIS, isotopically labeled internal standards; IS, internal standard; ISD, immunosuppressive drugs; LLE, liquid–liquid extraction; ME, matrix effects; MEPS, micro extraction in packed sorbent; MPA, mycophenolic acid; OF, ora

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Determination of a novel phosphodiesterase-4 inhibitor chlorbipram in mouse plasma and brain by UFLC–MS/MS: Application in pharmacokinetic studies after intravenous administration

Keywords: استاندارد داخلی; PDE4, phosphodiesterase-4; UFLC–MS/MS, ultra-fast liquid chromatography-tandem mass spectrometry; MRM, multiple reaction monitoring; ESI, electrospray ionization; IS, internal standard; cAMP, cyclic AMP; CREB, cAMP response element-binding protein; BDNF,

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Determination of efonidipine in human plasma by LC–MS/MS for pharmacokinetic applications

Keywords: استاندارد داخلی; DHP, dihydropyridine; HR, heart rate; CKD, chronic kidney disease; BP, blood pressure; IS, internal standard; LLOQ, lower limit of quantification; QC, quality control; ULOQ, upper limit of quantification; ESI, electrospray ionization; DP, declustering pot

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Quantification of new antiepileptic drugs by liquid chromatography/electrospray ionization tandem mass spectrometry and its application to cellular uptake experiment using human placental choriocarcinoma BeWo cells

Keywords: استاندارد داخلی; GBP, gabapentin; IS, internal standard; LC/MS/MS, liquid chromatography/tandem mass spectrometry; LEV, levetiracetam; LLOQ, lower limit of quantification; LTG, lamotrigine; R.E., relative error; R.S.D., relative standard deviation; SRM, selected reaction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Simultaneous determination of andrographolide, dehydroandrographolide and neoandrographolide in dog plasma by LC–MS/MS and its application to a dog pharmacokinetic study of Andrographis paniculata tablet

Keywords: استاندارد داخلی; AP, andrographolide; DP, dehydroandrograpolide; NP, neoandrograpolide; BB, bilobalide; IS, internal standard; A. paniculata, Andrographis paniculata; MRM, multiple reaction monitoring; LC–MS/MS, liquid chromatography–tandem mass spectrometry; QC, quality

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Method development for quantification of the environmental neurotoxin annonacin in Rat plasma by UPLC–MS/MS and application to a pharmacokinetic study

Keywords: استاندارد داخلی; AAG, Annonaceous acetogenin; amu, atomic mass unit; AUC, area under curve; Cl, clearance; EMA, Eropean Medicines Agency; F, obsapparent bioavailability; IS, internal standard; LLOQ, lower limit of quantification; MF, matrix factor; MQC, medium concentrati

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Bio-analytical method based on MALDI-MS analysis for the quantification of CIGB-300 anti-tumor peptide in human plasma

Keywords: استاندارد داخلی; MALDI-TOF MS, Matrix Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry; QCs, quality control samples; CSs, calibration standard samples; TFA, trifluoroacetic acid; IS, internal standard; LLOQ, lower limit of quantification; AUC, area u

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Microextraction by packed sorbent (MEPS) to analyze catecholamines in innovative biological samples

Keywords: استاندارد داخلی; CAs, catecholamines; NE, norepinephrine; E, epinephrine; DA, dopamine; IS, internal standard; DUS, dried urine spot; DPS, dried plasma spot; MEPS, microextraction by packed sorbent; PPT, protein precipitation; SPE, solid phase extraction; LLE, liquid–liqu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

On-cartridge derivatization coupled with solid-phase extraction for the ultra-sensitive determination of minodronic acid in human plasma by LC–MS/MS method

Keywords: استاندارد داخلی; AA, alendronic acid; BP, bisphosphonate; D4-MA, D4-minodronic acid; HQC, high QC; IMF, IS-normalized matrix factor; IS, internal standard; LLOQ, lower limit of quantification; LQC, low QC; MA, minodronic acid; MQC, medium QC; MRM, multiple reaction monito

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Comprehensive analysis of the lipophilic reactive carbonyls present in biological specimens by LC/ESI-MS/MS

Keywords: استاندارد داخلی; AA, arachidonic acid; DH, dansyl hydrazine; DHA, docosahexaenoic acid; 2,4-DDE, 2,4-decadienal; EDE, 4,5-epoxy-2-decenal; 2,4-HxDE, 2,4-hexadienal; 2,4-HpDE, 2,4-heptadienal; HNE, 4-hydroxy-2-nonenal; IS, internal standard; LA, linoleic acid; LC/ESI-MS/MS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Novel LC–MS/MS method for plasma vancomycin: Comparison with immunoassays and clinical impact

Keywords: استاندارد داخلی; LC–MS/MS, liquid chromatography–tandem mass spectrometry; TDM, therapeutic drug monitoring; IS, internal standard; QC, quality control; MRM, multiple reaction monitoring; S/N, signal to noise ratio; CV, coefficient of variation; ME, matrix effect; DR, det

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Pharmacokinetic study of salvianolic acid D after oral and intravenous administration in rats

Keywords: استاندارد داخلی; AUC, the area under curve; CI, confidence interval; CL, clearance; Cmax, peak plasma concentration; ECE-1, endothelin converting enzyme 1; ESI, electrospray ionization; IS, internal standard; LLOQ, lower limit of quantification; QC, quality control; R.E.,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of in vitro primary metabolic profile of SKLB-M8, a novel antitumor compound, using liquid chromatography coupled with triple quadrupole tandem mass spectrometry and quadrupole time-of-flight tandem mass spectrometry

Keywords: استاندارد داخلی; CID, collision-induced dissociation; CLint, intrinsic clearance; DLMs, dog liver microsomes; ESI, electrospray ionization; h, Hill coefficient; HLMs, human liver microsomes; IC50, half maximal inhibitory concentration; IS, internal standard; M1-4, metabol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

LC-ESI–MS/MS method for bioanalytical determination of osteogenic phytoalexin, medicarpin, and its application to preliminary pharmacokinetic studies in rats

Keywords: استاندارد داخلی; ESI, electrospray ionization; IS, internal standard; LC, liquid chromatography; LLOQ, lower limit of quantification; MRM, multiple reaction monitoring; SD, Sprague–Dawley; Vd, volume of distribution; Cl, clearanceBioavailability; Pharmacokinetics; Bioanal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Validation of a UPLC–MS/MS method for the simultaneous determination of E6005, a phosphodiesterase 4 inhibitor, and its metabolite in human plasma

Keywords: استاندارد داخلی; HQ, Chigh QC; IS, internal standard; LLOQ, lower limit of quantification; LQC, low QC; MQC, middle QC; PDE, phosphodiesterase; QC, quality control; RE, relative error; RSD, relative standard deviations; ULOQ, upper limit of quantification; UPLC–MS/MS, ult

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Measurement of intracellular ribavirin mono-, di- and triphosphate using solid phase extraction and LC–MS/MS quantification

Keywords: استاندارد داخلی; RBV, ribavirin; NA, nucleoside analog; MP, monophosphate; DP, diphosphate; TP, triphosphate; IS, internal standard; hPBMC, human peripheral blood mononuclear cells; SPE, solid phase extraction; RBC, red blood cells; DBS, dried blood spots; UP, ultrapure;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Development and validation of an efficient ultrasound assisted extraction of phenolic compounds from flax (Linum usitatissimum L.) seeds

Keywords: استاندارد داخلی; CafG, caffeic acid glucoside; DW, dry weight; FerG, ferulic acid glucoside; HCAG, hydroxy cinnamic acid glucosides; HDG, herbacetin di-glucoside; HMG, hydroxy methyl glutaryl; HMGA, hydroxy methyl glutaric acid; IS, internal standard; LOD, limit of detect

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Floating lipid beads for the improvement of bioavailability of poorly soluble basic drugs: In-vitro optimization and in-vivo performance in humans

Keywords: استاندارد داخلی; ANOVA, analysis of variance; AUC, area under the curve; Cmax, peak concentration; CNZ, Cinnarizine; DSC, differential scanning calorimetry; Gel, Gelucire; h, hour; IS, internal standard; LC-MS/MS, liquid chromatography mass spectroscopy; SEM, scanning ele

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Study of pharmacokinetic profiles and characteristics of active components and their metabolites in rat plasma following oral administration of the water extract of Astragali radix using UPLC–MS/MS

Keywords: استاندارد داخلی; TCM, traditional Chinese medicine; LC–MS/MS, ultra-performance liquid chromatography–electrospray ionization–mass spectrometry; UGT, UDP-glucuronosyltransferase; IS, internal standard; C-3′-G, calycosin-3′-glucuronide; CG, calycosin-7-β-glucoside; CG-3′-G

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Highly sensitive method for simultaneous determination of nine alkaloids of Shuanghua Baihe tablets in human plasma by LC–MS/MS and its application

Keywords: استاندارد داخلی; SBT, Shuanghua Baihe tablets; RAS, recurrent aphthous stomatitis; TCM, traditional Chinese medicine; TCMs, traditional Chinese medicines; LLOQ, lower limit of quantification; IS, internal standard; MRM, multiple reaction monitoring; PPT, protein precipita

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Simultaneous determination of oxiracetam and its degraded substance in rat plasma by HPLC-MS/MS and its application to pharmacokinetic study after a single high-dose intravenous administration

Keywords: استاندارد داخلی; HOPAA, 4-hydroxy-2-oxo-1-pyrrolidine acetic acid; IS, internal standard; MRM, multiple reaction monitoring; ESI, electrospray ionization; QC, quality control; LLOQ, lower limit of quantification; RE, relative error; RSD, relative standard deviation.Simult

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Determination of irinotecan and its metabolite SN-38 in rabbit plasma and tumors using a validated method of tandem mass spectrometry coupled with liquid chromatography

Keywords: استاندارد داخلی; CPT, camptothecin; CPT-11, irinotecan; CV, coefficient of variation; IS, internal standard; LLE, liquid-liquid extraction; MRM, multiple reaction monitoring; SD, standard deviationIrinotecan; SN-38; Camptothecin; Rabbit; VX2 tumor; LC–MS/MS

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

No endogenous ouabain is detectable in human plasma by ultra-sensitive UPLC-MS/MS

Keywords: استاندارد داخلی; EDLF, endogenous digitalis like factor; OLC, ouabain-like compound; EO, endogenous ouabain; ACTH, adrenocorticotropic hormone; LC-MS, liquid chromatography mass spectrometry; API, atmospheric pressure ionization; QC, quality control; IS, internal standard

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Determination of a deuterohemin–peptide conjugate in rat plasma by liquid chromatography–tandem mass spectrometry and application to a preclinical pharmacokinetic study

Keywords: استاندارد داخلی; DhHP-6, deuterohemin–peptide conjugate; LC–MS/MS, liquid chromatography tandem mass spectrometry; IS, internal standard; ROS, reactive oxygen species; H2O2, hydrogen peroxide; MRM, multiple reaction monitoring; HCl, hydrochloric acid; FDA, US Food and Dru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه