دانلود مقالات ISI درباره JAK2، Janus kinase 2 + ترجمه فارسی

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A multicenter prospective study of risk factors and treatment of unusual site thrombosis

Keywords: JAK2، Janus kinase 2; USDVT, unusual site deep vein thrombosis; VTE, venous thromboembolism; DVT, deep vein thrombosis; PE, pulmonary embolism; PVT, portal vein thrombosis; CVC, central venous catheter; JAK2, Janus kinase 2; CT, computed tomography; MR, magnetic resonance; UFH

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

PAK1 در واکنش به پرولاکتین به هسته تبدیل می شود، اما نه به استروژن

PAK1 translocates into nucleus in response to prolactin but not to estrogen

Keywords: JAK2، Janus kinase 2; PAK1; Tyrosyl phosphorylation; Prolactin; EstrogenE2, 17β-estradiol; EGF, epidermal growth factor; JAK2, Janus kinase 2; NLS, nuclear localization signal; PAK, p21-activated serine–threonine kinase; PRL, prolactin; pTyr, phosphorylated on tyrosines; Tyr,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Natural killer cells in patients with polycythemia vera

Keywords: JAK2، Janus kinase 2; NK, natural killer; PV, polycythemia vera; JAK2, janus kinase 2; MPD, myeloproliferative disorders; Ph1, phildadelphia; HLA, human leukocyte antigen; STAT, signal transducer and activator of transcription; CML, chronic myeloid leukemia; KIRs, inhibitory k

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Protein tyrosine phosphatase 1B (PTP1B) is involved in the defective erythropoietic function of carbamylated erythropoietin

Keywords: JAK2، Janus kinase 2; Erythropoietin; Carbamylated erythropoietin; PTP1B; Cell proliferation; Tyrosine phosphatasesβcR, beta common receptor; cEpo, carbamylated erythropoietin; Epo, erythropoietin; EpoR, erythropoietin receptor; FBS, fetal bovine serum; Jak2, Janus kinase 2; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Mesenteric Venous Thrombosis

Keywords: JAK2، Janus kinase 2; mesenteric venous thrombosis; portal hypertension; thrombosisMVT, mesenteric venous thrombosis; TIPS, transjugular intrahepatic portosystemic shunt; PVT, portal vein thrombosis; JAK2, janus kinase 2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Genistein stimulates fatty acid oxidation in a leptin receptor-independent manner through the JAK2-mediated phosphorylation and activation of AMPK in skeletal muscle

Keywords: JAK2، Janus kinase 2; FFA, free fatty acids; FAO, fatty acid oxidation; SP, soy protein; JAK2, Janus kinase 2; AMPK, 5′-adenosine monophosphate-activated protein kinase; ACC, acetyl CoA carboxylase; PPARα, peroxisome proliferator-activated receptor-α; PPARδ, peroxisome prolife

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Erythropoietin-mediated protection of insect brain neurons involves JAK and STAT but not PI3K transduction pathways

Keywords: JAK2، Janus kinase 2; βc-R, β common receptor; Epo, erythropoietin; EpoR, Epo receptor; GM, gentamicin; JAK2, Janus kinase 2; MAPK, mitogen-activated protein kinase; PBS, phosphate-buffered saline; PI3K, phosphoinositol-3-kinase; PI3K/Akt, phosphoinositol-3-kinase/protein kina

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Bone marrow-derived myofibroblasts promote colon tumorigenesis through the IL-6/JAK2/STAT3 pathway

Keywords: JAK2، Janus kinase 2; BMFs, bone marrow-derived myofibroblasts; BMF-CM, BMF conditioned medium; Co-culture-CM, co-culture medium of BMFs and cancer cells; IL-6, interleukin-6; JAK2, janus kinase 2; STAT3, signal transducer and activator of transcription 3; CAFs, cancer-associa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Sesquiterpene dimmer (DSF-27) inhibits the release of neuroinflammatory mediators from microglia by targeting spleen tyrosine kinase (Syk) and Janus kinase 2 (Jak2): Two major non-receptor tyrosine signaling proteins involved in inflammatory events

Keywords: JAK2، Janus kinase 2; NRPTKs, non-receptor protein tyrosine kinases; Jak2, Janus kinase 2; LPS, lipopolysaccharide; IL-6, interleukin-6; IL-1β, interleukin-1β; TNF-α, tumor necrosis factor-α; NO, nitric oxide; PIAS, protein inhibitors of activated STAT; IKK, IκB kinase; NF-κB,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Effect of genetic variations within the SH2B2 gene on the growth of Chinese cattle

Keywords: JAK2، Janus kinase 2; JAK2, Janus kinase 2; SH2B2, Src homology 2 B 2; SNPs, single nucleotide polymorphisms; PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism; APS, adapter protein with a PH and SH2 domain; SH2B, Src homology 2 B; HWE, Hardy–Weinber

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Da-Huang-Fu-Zi-Tang attenuates liver injury in rats with severe acute pancreatitis

Keywords: JAK2، Janus kinase 2; ANOVA, analysis of variance; ELISA, enzyme-linked immunosorbent assay; HE, hematoxylin and eosin; HPLC–MS, high performance liquid chromatography–mass spectrometry; JAK2, Janus kinase 2; KCs, Kupffer cells; PBS, phosphate buffered saline; SAP, severe acut

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

JAK2 inhibition is neuroprotective and reduces astrogliosis after quinolinic acid striatal lesion in adult mice

Keywords: JAK2، Janus kinase 2; CNS, central nervous system; CNTF, ciliary neurotrophic factor; DMSO, dimethyl sulfoxide; GFAP, glial fibrillary acidic protein; IL-6, interleukin-6; NMDA, N-methyl-d-aspartic acid; QA, quinolinic acid; JAK2, Janus Kinase 2; STAT, signal transducer and ac

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Stat3 pathway correlates with the roles of leptin in mouse liver fibrosis and sterol regulatory element binding protein-1c expression of rat hepatic stellate cells

Keywords: JAK2، Janus kinase 2; Jak2, Janus kinase 2; Stat3, signal transducer and activator of transcription 3; HSC, hepatic stellate cell; SREBP-1c, sterol regulatory element binding protein-1c; LXR, liver X receptor; FBS, fetal bovine serum; DMEM, Dulbecco's modified Eagle's medium;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Design, synthesis and biological evaluation of β-carboline derivatives as novel inhibitors targeting B-Raf kinase

Keywords: JAK2، Janus kinase 2; B-Raf kinase inhibitor; β-Carboline derivatives; Kinase inhibitory activitiesMAPK, mitogen-activated protein kinase; IC50, half maximal inhibitory concentration; JAK2, janus kinase 2; CDK, cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Prolactin-releasing peptide is a potent mediator of the innate immune response in leukocytes from Salmo salar

Keywords: JAK2، Janus kinase 2; DPI, dibenziodolium chloride; PRL, prolactin; ROS, reactive oxygen species; PKC, protein kinase C; PRL, prolactin; PRLR, PRL receptor; IL, interleukin; HK, head kidney; Jak2, Janus kinase 2; TLR, Toll Like Receptor; PMA, phorbol myristate acetate; NF-κB,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Alternately binding probe competitive PCR as a simple, cost-effective, and accurate quantification method for JAK2V617F allele burden in myeloproliferative neoplasms

Keywords: JAK2، Janus kinase 2; MPNs, myeloproliferative neoplasms; PV, polycythemia vera; ET, essential thrombocythemia; PMF, primary myelofibrosis; JAK2, janus kinase 2; AS-qPCR, allele-specific quantitative PCR; ABC-PCR, alternately binding probe competitive PCR; AB-Probe, alternatel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of Lactobacillus reuteri GMNL-263 treatment on renal fibrosis in diabetic rats

Keywords: JAK2، Janus kinase 2; α-SMA, α-smooth muscle actin; DN, diabetic nephropathy; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; JAK2, Janus kinase 2; JNK, c-Jun N-terminal kinase; MAPK, mitogen-activated protein kinase; PAI-1, plasminogen activator inhibit

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts

Keywords: JAK2، Janus kinase 2; α-SMA, α-smooth muscle actin; DN, diabetic nephropathy; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; HG, high glucose; HM, high mannitol; JAK2, Janus kinase 2; JNK, c-Jun N-terminal kinase; LDH, lactate dehydrogenase; MAPK, mitog

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Protein kinase Cμ mediates adenosine-stimulated steroidogenesis in primary rat adrenal cells

Keywords: JAK2، Janus kinase 2; Ado, adenosine; AR, adenosine receptor; CREB, cyclic AMP responsive-element binding protein; ERK, extracellular signal-related regulated kinase; GPCRs, G protein-coupled receptors; JAK2, Janus kinase 2; MEK, mitogen-activated protein kinase kinase; PKC, p

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFκB/HIF-1α activation

Keywords: JAK2، Janus kinase 2; MT, mammary tumor cells; VEGF, vascular endothelial growth factor; VEGFR2, vascular endothelial growth factor receptor 2; ER, estrogen receptor; JAK2, Janus kinase 2; STAT3, signal transducer and activator of transcription 3; ERK 1/2, extracellular signal

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: Central role for JAK2 activation of STAT3 and NF-κB

Keywords: JAK2، Janus kinase 2; Ang II, angiotensin II; JAK2, Janus kinase 2; MLA, methyllycaconitine; NF-κB, nuclear factor-kappa B; nAChR, nicotinic acetylcholine receptor; PBS, phosphate-buffered saline; PC12, Pheochromocytoma-derived cell line; SHP-1, Src homology phosphatase-1; STA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: Failure of Stat5 activation and functional differentiation in the absence of Elf5

Keywords: JAK2، Janus kinase 2; AQP5, aquaporin 5; Cldn7, claudin 7; Elf5, E74-like factor 5; ERα, estrogen receptor alpha; ES, embryonic stem; ESE, epithelium specific Ets; Ets, E twenty-six; Id2, inhibitor of DNA binding 2; IKKα, inhibitor of kappa B kinase alpha; Jak2, janus kinase 2

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

The chemokine CCL2 activates p38 mitogen-activated protein kinase pathway in cultured rat hippocampal cells

Keywords: JAK2، Janus kinase 2; CREB, cAMP response element-binding protein; BDNF, brain derived neurotrophic factor; CNS, central nervous system; HIV, human immunodeficiency virus; JAK2, Janus kinase 2; STAT, signal transducer and activator of transcription; MAPK, mitogen-activated pro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Signal transducers and activators of transcription 5 contributes to erythropoietin-mediated neuroprotection against hippocampal neuronal death after transient global cerebral ischemia

Keywords: JAK2، Janus kinase 2; EPO, erythropoietin; ICV, intracerebral ventricle; JAK2, Janus kinase 2; STAT5, signal transducer and activator of transcription 5; XIAP, X-linked inhibitor of apoptosis proteinSTAT5; CA1; Ischemia; EPO

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis

Keywords: JAK2، Janus kinase 2; JAK2, Janus kinase 2; SOCS, suppressor of cytokine signaling; STAT3, signal transducer and activator of transcription 3; TRAIL, tumor necrosis factor-related apoptosis-inducing ligandSTAT3; AG490; TRAIL; Hepatoma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Chronic idiopathic myelofibrosis (CIMF) resulting from a unique 3;9 translocation disrupting the janus kinase 2 (JAK2) gene

Keywords: JAK2، Janus kinase 2; 3;9 translocation; CMPD, chronic myeloproliferative disorder; CIMF, chronic idiopathic myelofibrosis; FISH, fluorescent in situ hybridization; JAK2, janus kinase 2; t(3;9)(q21;p24)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

The coffee diterpene kahweol inhibits tumor necrosis factor-α-induced expression of cell adhesion molecules in human endothelial cells

Keywords: JAK2، Janus kinase 2; Akt, protein kinase B; GFP, green fluorescent protein; ICAM, intercellular cell adhesion molecule; IκBα, inhibitor κBα; JAK2, Janus kinase 2; NF-κB, nuclear factor-κB; PI3K, phosphatidylinositol-3 kinase; TNFα, tumor necrosis factor-α; VCAM, vascular cell

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه