دانلود مقالات ISI درباره JNK، c-Jun NH2-terminal kinase + ترجمه فارسی

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Fluvoxamine alleviates paclitaxel-induced neurotoxicity

Keywords: JNK، c-Jun NH2-terminal kinase; BiP, immunoglobulin heavy-chain binding protein; BIX, BiP inducer X; CACI, chemotherapy-associated cognitive impairments; CHOP, C/EBP homologous protein; CYP, cytochrome P450; ER, endoplasmic reticulum; Flv, fluvoxamine; JNK, c-Jun NH2-terminal kinase; Px

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells

Keywords: JNK، c-Jun NH2-terminal kinase; ERK, extracellular signal-regulated kinase; IL-1β, interleukin-1β; IL-6, interleukin-6; iNOS, inducible nitric oxide synthase; IκBα, inhibitor of nuclear factor ΚBα; JNK, c-Jun NH2-Terminal Kinase; LPS, lipopolysaccharide; MAPK, mitogen-activated protein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Gene expression profiles predict the possible regulatory role of OPN-mediated signaling pathways in rat liver regeneration

Keywords: JNK، c-Jun NH2-terminal kinase; AKT, v-akt murine thymoma viral oncogene homolog 1; Bcl2, B-cell CLL/lymphoma 2; ERK, extracellular regulated protein kinases; Fos, FBJ osteosarcoma oncogene; IKBKB, inhibitor of κB kinase β; JAK, Janus kinase; JNK, c-Jun NH2-terminal kinase; Jun, jun pro

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Cardenolides from the Apocynaceae family and their anticancer activity

Keywords: JNK، c-Jun NH2-terminal kinase; TCM, traditional Chinese medicine; ODS column, Octadecylsilyl; RP-HPLC, reverse phase high-performance liquid chromatography; NMR, Nuclear Magnetic Resonance; NF-κB, Nuclear Factor-kappaB; JNK, c-Jun NH2-terminal kinase; AP-1, Activator Protein-1; ROS, re

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Mangiferin ameliorates colitis by inhibiting IRAK1 phosphorylation in NF-κB and MAPK pathways

Keywords: JNK، c-Jun NH2-terminal kinase; Mangiferin; Colitis; Macrophage; IRAK1; NF-κB; MAP kinaseCOX, cyclooxygenase; ERK, extracellular signal-regulated kinase; IKK, IκB kinase; IL, interleukin; IRAK, interleukin-1 receptor-associated kinase; JNK, c-Jun NH2-terminal kinase; LPS, lipopolysaccha

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Protective effects of Acanthopanax divaricatus vat. albeofructus and its active compound on ischemia–reperfusion injury of rat liver

Keywords: JNK، c-Jun NH2-terminal kinase; AD, acanthoside-D; AE, water extract of Acanthopanax divaricatus vat. albeofructus; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CAT, catalase; GSH-Px, glutathione peroxidase; JNK, c-Jun NH2-terminal kinase; M

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Angiotensin II promotes cardiac differentiation of embryonic stem cells via angiotensin type 1 receptor

Keywords: JNK، c-Jun NH2-terminal kinase; AT1R, angiotensin type 1 receptor; Ang II, angiotensin II; ESCs, embryonic stem cells; ERK, extracellular-signal regulated kinase; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinaseAngiotensin type 1 receptor; Cardiac differentiation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Cadmium activates extracellular signal-regulated kinase 5 in HK-2 human renal proximal tubular cells

Keywords: JNK، c-Jun NH2-terminal kinase; ATF-1, activating transcription factor-1; CdCl2, cadmium chloride; CREB, cAMP response element-binding protein; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; M

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

PKCα inhibited apoptosis by decreasing the activity of JNK in MCF-7/ADR cells

Keywords: JNK، c-Jun NH2-terminal kinase; PKC, protein kinase C; JNK, c-Jun NH2-terminal kinase; MDR, multidrug resistant; TAM, tamoxifen; DCC-FBS, fatal bovine serum stripped with dextrin-coated charcoal; SP, sp600125; Go, Go6976Apoptosis; MDR; PKCα; JNK; Breast cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Modified Wu-Zi-Yan-Zong prescription, a traditional Chinese polyherbal formula, suppresses lipopolysaccharide-induced neuroinflammatory processes in rat astrocytes via NF-κB and JNK/p38 MAPK signaling pathways

Keywords: JNK، c-Jun NH2-terminal kinase; LPS, lipopolysaccharide; MWP, modified Wu-Zi-Yan-Zong prescription; NF-κB, nuclear factor kappa-B; MAPK, mitogen-activated protein kinase; JNK, c-Jun NH2-terminal kinase; Iκ-B, inhibitor of nuclear factor-κB; IKK, Iκ-B kinase; iNOS, inducible nitric oxide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

NK026680 inhibits T-cell function in an IL-2-dependent manner and prolongs cardiac allograft survival in rats

Keywords: JNK، c-Jun NH2-terminal kinase; AP-1, activator protein-1; CNI, calcineurin inhibitor; DC, dendritic cell; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; MLR, mixed lymphocyte reaction; MST, median survival time; NF-κB

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Cadmium-induced apoptosis in the BJAB human B cell line: Involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression

Keywords: JNK، c-Jun NH2-terminal kinase; HO-1, heme oxygenase-1; CO, carbon monoxide; ERK ½, extracellular signal-regulated protein kinase ½; JNK, c-Jun NH2-terminal kinase; PKC, protein kinase C; MAPK, mitogen-activated protein kinase; PI3-kinase, phosphatidyl 3-kinase; ROS, reactive oxygen spe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

CD40-mediated cell death requires TRAF6 recruitment

Keywords: JNK، c-Jun NH2-terminal kinase; AO, acridine orange; AP-1, activator protein-1; APCs, antigen presenting cells; AV, annexin V; db, disulfide bond; ERK, extracellular signal-regulated kinase; Jak3, Janus kinase 3; JNK, c-Jun NH2-terminal kinase; LMP, lysosomal membrane permeabilization;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of aldehyde dehydrogenase 2 activity enhances antimycin-induced rat cardiomyocytes apoptosis through activation of MAPK signaling pathway

Keywords: JNK، c-Jun NH2-terminal kinase; Aldehyde dehydrogenase 2; Cardiomyocyte; ApoptosisALDH2, Aldehyde dehydrogenase 2; ERK1/2, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; ROS, reactive oxygen species; 4-HNE, 4-hydroxy-2-nonenal; DCF-DA, 2′,7′-dichlorofluorescein d

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Syk mediates BCR- and CD40-signaling integration during B cell activation

Keywords: JNK، c-Jun NH2-terminal kinase; Ab, antibody; Ag, antigen; BLNK, B cell linker; BM, bone marrow; Btk, Bruton tyrosine kinase; ERK, extracellular signal regulated kinase; IP3, inositol 1,4,5-trisphosphate; JNK, c-Jun NH2-terminal kinase; PKC, protein kinase C; MAPK, mitogen-activated pro

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells

Keywords: JNK، c-Jun NH2-terminal kinase; AP-1, activator protein-1; CdCl2, cadmium chloride; Ct, threshold cycle; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated protein kinase; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; PBS, phosphate-buffered saline;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Differential expression of toll-like receptor signaling cascades in LPS-tolerant human peripheral blood mononuclear cells

Keywords: JNK، c-Jun NH2-terminal kinase; ERK, extracellular regulated kinase; Jnk, c-Jun NH2-terminal kinase; LBP, lipopolysaccharide binding protein; LPS, lipopolysaccharide; MAPK, mitogen-activated protein kinase; NF-κB, nuclear factor κB; PBMC, peripheral blood mononuclear cells; PCR, polymer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

An acidic pH environment increases cell death and pro-inflammatory cytokine release in osteoblasts: The involvement of BAX Inhibitor-1

Keywords: JNK، c-Jun NH2-terminal kinase; Ca2+, calcium; BI-1, BAX Inhibitor-1; GRP78, glucose response protein78; CHOP, C/EBP homologous protein; eIF2α, eukaryotic translation initiation factor-2α; JNK, c-Jun NH2-terminal kinase; IL-1, Interleukin-1; TNF, tumor necrosis factorCell death; Osteobl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Interplay of Posttranslational Modifications in Sp1 Mediates Sp1 Stability during Cell Cycle Progression

Keywords: JNK، c-Jun NH2-terminal kinase; SUMO, small ubiquitin-like modifier; JNK, c-Jun NH2-terminal kinase; STUbL, SUMO-targeted ubiquitin ligase; SIM, SUMO interaction motif; PML, promyelocytic leukemia; NEM, N-ethyl maleimide; GST, glutathione S-transferase; GFP, green fluorescent protein; w

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Crystal structures of MKK4 kinase domain reveal that substrate peptide binds to an allosteric site and induces an auto-inhibition state

Keywords: JNK، c-Jun NH2-terminal kinase; JNK, c-Jun NH2-terminal kinase; MAP, mitogen-activated protein; MKK, MAP kinase kinase; MKKK, MAP kinase kinase kinase; IPTG, isopropyl-β-d-thiogalactopyranoside; npMKK4, non-phosphorylated MKK4 kinase domain; AMP–PNP, adenylyl-imidodiphosphate; rmsd, roo

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Neuroprotective effect of modified Wu-Zi-Yan-Zong granule, a traditional Chinese herbal medicine, on CoCl2-induced PC12 cells

Keywords: JNK، c-Jun NH2-terminal kinase; MWG, modified Wu-Zi-Yan-Zong granule; MAPK, mitogen-activated protein kinase; CCK-8, Cell Counting Kit-8; MMP, mitochondrial membrane potential; ROS, reactive oxygen species; PARP, poly ADP-ribose polymerase; JNK, c-Jun NH2-terminal kinase; SD, senile dem

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Cochlear protection from acoustic injury by inhibitors of p38 mitogen-activated protein kinase and sequestosome 1 stress protein

Keywords: JNK، c-Jun NH2-terminal kinase; p38 MAPK; sequestosome 1; p62; A170; acoustic injury; cochleaABR, auditory brainstem response; JNK, c-Jun NH2-terminal kinase; Nrf2, NF-E2-related factor 2; p38 MAPK, p38 mitogen-activated protein kinase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Isoenzyme profile of glutathione transferases in transitional cell carcinoma of upper urinary tract

Keywords: JNK، c-Jun NH2-terminal kinase; BEN, Balkan endemic nephropathy; CDNB, 1-chloro-2,4-dinitrobenzene; EPNP, 1,2-epoxy-3-(p-nitrophenoxy)propane; GSH, glutathione; GST, glutathione S-transferase; GSTM, GST Mu; GSTP, GST Pi; GSTT, GST Theta; JNK, c-Jun NH2-terminal kinase; TCC, transitional

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibition characteristics of hypericin on rat small intestine glutathione-S-transferases

Keywords: JNK، c-Jun NH2-terminal kinase; GST, glutathione-S-transferase; JNK, c-Jun NH2-terminal kinase; GSH, reduced glutathione; CDNB, 1-chloro-2,4-dinitrobenzene; PDT, photodynamic therapy; ROS, reactive oxygen species; CYP2C19, cytochrome P450 2C19; CYP2D6, cytochrome P450 2D6; CYP3A4, cytoc

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

DJ-1, a cancer and Parkinson’s disease associated protein, regulates autophagy through JNK pathway in cancer cells

Keywords: JNK، c-Jun NH2-terminal kinase; ANOVA, analysis of variance; Atg, autophagy-related protein; EGFP, enhanced green fluorescent proteins; ERK, extracellular signal-regulated kinase; HBSS, Hanks’ balanced salt solution; HRP, horseradish peroxidase; JNK, c-Jun NH2-terminal kinase; MDC, Mono

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Pathological roles of MAPK signaling pathways in human diseases

Keywords: JNK، c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; MAP3K, MAPK kinase kinase; MAP2K, MAPK kinase; KSR, kinase suppressor of Ras-1; MP1, MEK partner 1; JIP, JNK-interacting protein; TNF, tumo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

The development of MDA-7/IL-24 as a cancer therapeutic

Keywords: JNK، c-Jun NH2-terminal kinase; MDA-7; IL-24; Apoptosis; Autophagy; Ceramide; ROS; Ca2+; Clinical trial; Signal transduction; PERK; ER stress; MCL-1ERK, extracellular regulated kinase; MEK, mitogen activated extracellular regulated kinase; JNK, c-Jun NH2-terminal kinase; PI3K, phosphati

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Cryptotanshinone sensitizes DU145 prostate cancer cells to Fas(APO1/CD95)-mediated apoptosis through Bcl-2 and MAPK regulation

Keywords: JNK، c-Jun NH2-terminal kinase; MAPK, Mitogen-activated protein kinase; JNK, c-Jun NH2-terminal kinase; ERK, extracellular signal-regulated kinase; FADD, Fas-associated protein with death domain; FAF, Fas-associated factor; FACS, fluorescence-activated cell sorting, 5-FU, fluorouracil;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Zinc protoporphyrin inhibition of lipopolysaccharide-, lipoteichoic acid-, and peptidoglycan-induced nitric oxide production through stimulating iNOS protein ubiquitination

Keywords: JNK، c-Jun NH2-terminal kinase; BSA, bovine serum albumin; FBS, fetal bovine serum; HO-1, heme oxygenase-1; ERK, extracellular signal-regulated protein kinase; FePP, ferric protoporphyrin; iNOS, inducible nitric oxide synthase; JNK, c-Jun NH2-terminal kinase; LPS, lipopolysaccharide; LT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

α3β1 integrin promotes cell survival via multiple interactions between 14-3-3 isoforms and proapoptotic proteins

Keywords: JNK، c-Jun NH2-terminal kinase; YAP, Yes-associated protein; PI3K, phosphatidylinositol 3-kinase; JNK, c-Jun NH2-terminal kinase; Ln5-P4, PPFLMLLKGSTR motif; FAK, focal adhesion kinase; NHEKs, normal human epidermal keratinocytes; KGM, keratinocyte growth medium; MTT, 3-(4,5-dimethylthi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway

Keywords: JNK، c-Jun NH2-terminal kinase; ASK1, apoptosis signal-regulating kinase 1; Prx-1, peroxiredoxin 1; Trx, thioredoxin; H2O2, hydrogen peroxide; shRNA, short hairpin RNA; JNK, c-Jun NH2-terminal kinase; TNF-α, tumor necrosis factor alphaApoptosis; Apoptosis signal-regulating kinase 1; Per

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Epidermal growth factor stimulates Rac1 and p21-activated kinase in vascular smooth muscle cells

Keywords: JNK، c-Jun NH2-terminal kinase; AngII, angiotensin II; EGF, epidermal growth factor; ERK1/2, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; LPA, lysophosphatidic acid; MAP kinase, mitogen activated protein kinase; MBP, myelin basic protein; PAK, p21-activated kin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Tyrosine phosphorylation of HPK1 by activated Src promotes ischemic brain injury in rat hippocampal CA1 region

Keywords: JNK، c-Jun NH2-terminal kinase; GCK, germinal center kinase; HPK1, Hematopoietic progenitor kinase 1; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; MKK7, MAPK kinase; NMDAR, N-methyl-D-aspartate receptor; PCR, polymerase chain reaction; PMSF, phenylmethylsulflu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways

Keywords: JNK، c-Jun NH2-terminal kinase; BDNF, brain derived neurotrophic factor; DAT, dopamine transporter; ERK1/2, extracellular-signal regulated kinase 1/2; GDNF, glial-derived neurotrophic factor; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; PARP, poly [Aop] ribose

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Phosphatase PTP1B negatively regulates MyD88- and TRIF-dependent proinflammatory cytokine and type I interferon production in TLR-triggered macrophages

Keywords: JNK، c-Jun NH2-terminal kinase; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; IFN-β, interferon-β; LPS, lipopolysaccharide; MAPK, mitogen-activated protein kinase; MyD88, myeloid differentiation factor 88; PTP1B, protein tyrosine phosphatase-1B; TLR, toll-l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibition of c-Jun N-terminal kinase sensitizes tumor cells to flavonoid-induced apoptosis through down-regulation of JunD

Keywords: JNK، c-Jun NH2-terminal kinase; Flavonoids; Tumor cells; Apoptosis; JNK; JunDAP-1, activator protein-1; ERK, extracellular signal-regulated kinase; HOS, human osteosarcoma; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; MTT, 3-(4,5-dimethylthiazol-2yl-)-2,5-diph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization

Keywords: JNK، c-Jun NH2-terminal kinase; CK8, cytokeratin 8; CK18, cytokeratin 18; IF, intermediate filament; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; NPC, nasopharyngeal carcinomaCisplatin resistance; Cytokeratin 8; Nasopharyngeal carcinoma; Proteomics; Apoptosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226

Keywords: JNK، c-Jun NH2-terminal kinase; bFGF, basic fibroblast growth factor; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; FBS, fetal bovine serum; FACS, fluorescence-activated cell sorter; JNK, c-Jun NH2-terminal kinase; MAPKs, mitogen-activated protein kinases; MMPs,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

c-Jun NH2-terminal kinase mediates leptin-stimulated androgen-independent prostate cancer cell proliferation via signal transducer and activator of transcription 3 and Akt

Keywords: JNK، c-Jun NH2-terminal kinase; AIPC, androgen-independent prostate cancer; IGF-I, insulin-like growth factor-I; IL-6, interleukin-6; STAT3, signal transducer and activator of transcription 3; PI3K, phosphatidylinositol-3 kinase; JNK, c-Jun NH2-terminal kinase; JAK, Janus kinase; SIE, s

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Helioxanthin inhibits interleukin-1β-induced MIP-1β production by reduction of c-jun expression and binding of the c-jun/CREB1 complex to the AP-1/CRE site of the MIP-1β promoter in Huh7 cells

Keywords: JNK، c-Jun NH2-terminal kinase; MIP-1β, macrophage inflammatory protein-1β; IL-1β, interleukin-1β; HE-145, helioxanthin; MAPK, mitogen-activated protein kinase; JNK, c-jun NH2-terminal kinase; AP-1, activator protein-1; ATF2, activating transcription factor 2; SP600125, anthra[1,9-cd]py

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis

Keywords: JNK، c-Jun NH2-terminal kinase; AhR, aryl hydrocarbon receptor; AKR, aldo-keto reductase; B[a]P, benzo[a]pyrene; JNK, c-Jun NH2-terminal kinase; CYP, cytochrome P450; DEP, diesel exhaust particle; ERK, extracellular signal-regulated kinase; NB, nitrobenzene; αNF, α-naphthoflavone; NM, n

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Involvement of a Rho-ROCK-JNK pathway in arsenic trioxide-induced apoptosis in chronic myelogenous leukemia cells

Keywords: JNK، c-Jun NH2-terminal kinase; APL, acute promyelocytic leukemia; CML, chronic myelogenous leukemia; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; DN MKK, dominant negative MAPK kinase; MLC, myosin light chain; GEF, guanine nucleotide exchange factorArsenic tr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Carvedilol, a nonselective β-blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro

Keywords: JNK، c-Jun NH2-terminal kinase; AP-1, activator protein-1; CHF, chronic heart failure; Egr-1, early growth response factor-1; ELISA, enzyme-linked immunosorbent assay; ERK1/2, extracellular signal-regulated kinase 1/2; JNK, c-Jun NH2-terminal kinase; LPS, lipopolysaccharide; NF-κB, nucl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

A cytotoxin isolated from Agkistrodon acutus snake venom induces apoptosis via Fas pathway in A549 cells

Keywords: JNK، c-Jun NH2-terminal kinase; LAAO, l-amino acid oxidase; JNK, c-Jun NH2-terminal kinase; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,3-diphenyltetrazodium bromide; DISC, death-inducing signaling complex; Δψm,, mitochondrial transmembrane potential; DCF, 2′,7′-dichlorofluorescein; DCFH-DA, 2′

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

RB1CC1 insufficiency causes neuronal atrophy through mTOR signaling alteration and involved in the pathology of Alzheimer's diseases

Keywords: JNK، c-Jun NH2-terminal kinase; RB1CC1, RB1-inducible Coiled-Coil 1; RB1, retinoblastoma tumor suppressor; mTOR, mammalian target of rapamycin; TSC, tuberous sclerosis complex; AD, Alzheimer's disease; KO, knockout; JNK, c-Jun NH2-terminal kinase; TNF, tumor necrosis factor; NFT, neurof

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Progression of Heart Failure Was Suppressed by Inhibition of Apoptosis Signal-Regulating Kinase 1 Via Transcoronary Gene Transfer

Keywords: JNK، c-Jun NH2-terminal kinase; ANOVA, analysis of variance; ASK1, apoptosis signal-regulating kinase 1; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; LV, left ventricular; LVPWT, left ventricular posterior wall; MAP, mitogen-activated protein; MKK, mitogen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells

Keywords: JNK، c-Jun NH2-terminal kinase; (Ac)5GP, penta-acetyl geniposide; SMase, sphingomyelinase; NGF, nerve growth factor; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated protein kinase; JNK, c-Jun NH2-terminal kinase; RT-PCR, reverse transcription polymerase chain

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Hyperosmotic stress-induced caspase-3 activation is mediated by p38 MAPK in the hippocampus

Keywords: JNK، c-Jun NH2-terminal kinase; ABS, alkaline-buffered saline; BSA, bovine serum albumin; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; KRB, Krebs Ringer bicarbonate; MAPK, mitogen-activated protein kinase; NO, nitric oxide; PARP,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Obesity, Inflammation, and Insulin Resistance

Keywords: JNK، c-Jun NH2-terminal kinase; CRP, C-reactive protein; CVD, cardiovascular disease; FFA, free fatty acids; HFD, high-fat diet; IKKβ, inhibitor of NK-kB kinase β; IL-6, interleukin-6; IRS-1, insulin receptor substrate-1; JNK, c-Jun NH2-terminal kinase; MCP-1, monocyte chemoattractant p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases

Keywords: JNK، c-Jun NH2-terminal kinase; PF, paeoniflorin; ROS, reactive oxygen species; MAPK, the mitogen-activated protein kinases; ERK, extracellular regulated kinase; JNK, c-Jun NH2-terminal kinase; FCM, flow cytometer; FACS, fluorescence-activated cell sorter; ASCGE, alkaline single-cell ge

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه