Development of novel oxazolo[5,4-d]pyrimidines as competitive CB2 neutral antagonists based on scaffold hopping
Keywords: Cannabinoid; CB2 receptor; Neutral antagonist; oxazolo[5,4-d]pyrimidine; Boc; tert-butyloxycarbonyl; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary cells; CHO-CB2; Chinese hamster ovary cells expressing CB2 receptors; CHO-WT; Chinese ham