Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; DQ, dopaquinone; EE, ethyl ester; l-DOPA, l-3,4-dihydroxyphenylalanine; MM-GB/SA, molecular mechanics-generalized born/surface area; PBA, phenylbenzoic acid; SASA, solvent-accessible surface area; UV, ultra violet; VDW, van der WaalsInhibitor; MM-GB/SA; M
مقالات ISI L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین (ترجمه نشده)
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Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; CH, citron hydrosol; CIHS, citrus hydrosol; GC, gas chromatography; l-DOPA, l-3,4-dihydroxyphenylalanine; LH, lemon hydrosol; OH, orange hydrosol; t-BC, tert-butylcatechol; TYR, tyrosinaseHydrosols; Citrus; Tyrosinase; Inhibitors; Gas chromatography
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Chlorcinnamic acid; Synthesis; Mushroom tyrosinase; Inhibition; KineticsDMSO, dimethyl sulfoxide; l-DOPA, l-3,4-dihydroxyphenylalanine; IC50, the inhibitor concentrations leading to 50% activity lost; KIS, equilibrium constant of the inhibitor combining w
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; ADHD, attention deficit hyperactivity disorder; AP, acute pancreatitis; DA, dopamine; DOPAC, 3,4-dihydroxyphenylacetic acid; EDTA, ethylenediaminetetraacetic acid; HVA, homovanillic acid; L-DOPA, l-3,4-dihydroxyphenylalanine; MAO, monoamine oxidase; MAO-A
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; ABTS 2,2′, azino-bis(3-ethylbenzothiazoline-6-sulfonic acid); l-DOPA, L-3,4-dihydroxyphenylalanine; ConA, Concanavalin A; CBS, Centraalbureau voorLaccase; Yellow laccase; 454 pyrosequencing; Gene isolation; Inverse PCR; Dye decolorisation
l-DOPA-induced dyskinesia is associated with a deficient numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; 6-OHDA, 6-hydroxydopamine; AADC, aromatic amino acid decarboxylase; AIM, abnormal involuntary movements; ANOVA, Analysis of Variance; DA, dopamine; ISH, in situ hybridization; l-DOPA, l-3,4-Dihydroxyphenylalanine; LID, l-DOPA-induced dyskinesia; mfb, medi
Polypharmacology of dopamine receptor ligands
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; ACh, acetylcholine; AC, adenylyl cyclase; APO, apomorphine; PD, Parkinson’s disease; CNS, central nervous system; COMT, catecholamine O-methyl transferase; DML, designed multiple ligands; L-DOPA, L-3,4-dihydroxyphenylalanine; LID, L-DOPA induced dyskinesi
Identification and characterization of proteins with phenoloxidase-like activities in the sea urchin Strongylocentrotus nudus
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Biochemical characteristics; Coelomocyte; Phenoloxidase; Sea urchin (Strongylocentrotus nudus)PO, phenoloxidase; CLS, coelomocyte lysate supernatant; l-DOPA, L-3,4-dihydroxyphenylalanine; U, unit; EDTA, ethylenediaminetetraacetic acid disodium; DETC, sodi
Extracellular melanogenesis inhibitory activity and the structure-activity relationships of ugonins from Helminthostachys zeylanica roots
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; ERK, extracellular signal-regulated kinases; JNK, c-Jun N-terminal kinase; l-DOPA, l-3,4-dihydroxyphenylalanine; MITF, microphthalmia-associated transcription factor; MAPK, mitogen-activated protein kinaseHelminthostachys zeylanica; Tyrosinase; B16 melano
Serotonin transporter availability may moderate the association between perceiving stress and depressive tendencies — A SPECT with 5-HTTLPR genotyping study
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; FWHM, full width at half maximum; G × E, gene-by-environmental; GLM, generalized linear model; l-DOPA, l-3,4-dihydroxyphenylalanine; MDD, major depressive disorder; MRI, magnetic resonance imaging; PCR, polymerase chain reaction; PET, positron emission to
Structure-based modification of 3-/4-aminoacetophenones giving a profound change of activity on tyrosinase: From potent activators to highly efficient inhibitors
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Aminophenylethylidenethiosemicarbazide compounds; Tyrosinase activator; Tyrosinase inhibitor; SARs; Inhibition mechanism; Inhibitory kineticsSARs, structure-activity relationships; L-DOPA, L-3,4-dihydroxyphenylalanine; THSG, 2,3,5,4′-tetrahydroxystilbene-
Antioxidant activity of dopamine and L-DOPA in lipid micelles and their cooperation with an analogue of α-tocopherol
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; ABAP, 2,2′-azobis(2-methylpropionamidine) dihydrochloride; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; BBB, blood–brain barrier; DA, dopamine; HAT, Hydrogen Atom Transfer; HB, hydrogen bond; L-DOPA, L-3,4-dihydroxyphenylalanine; MeLin, me
D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; AMPT, DA: dopamine; D1R, D1 dopamine receptor; GFP, green fluorescent protein; L-dopa, l-3,4-dihydroxyphenylalanine; LID, L-dopa-induced dyskinesia; PD, Parkinson's disease; RT, room temperatureDopamine D1 receptor; Dyskinesia; Cellular localization; Memb
Mitogen- and stress-activated protein kinase 1 is required for specific signaling responses in dopamine-denervated mouse striatum, but is not necessary for l-DOPA-induced dyskinesia
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; AIMs, abnormal involuntary movements; CREB, cAMP-responsive element binding protein; D1R, D1 receptor; ERK, extracellular signal-regulated kinase; FosB, FBJ murine osteosarcoma viral oncogene homolog B; l-DOPA, L-3,4-dihydroxyphenylalanine; LID, l-DOPA-in
In vitro antibacterial analysis of phenoloxidase reaction products from the sea cucumber Apostichopus japonicus
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Sea cucumber (Apostichopus japonicus); Phenoloxidases; L-3,4-dihydroxyphenylalanine; Dopamine; Antibacterial effectsPO, phenoloxidase; L-DOPA, L-3,4-dihydroxyphenylalanine; SEM, scanning electron microscope; G−, gram-negative; G+, gram-positive; PBS, phos
Characterization of receptor of activated C kinase 1 (RACK1) and functional analysis during larval metamorphosis of the oyster Crassostrea angulata
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; RACK1, Receptor of activated C kinase 1; Ca-RACK1, The RACK1-homolog gene from Crassostrea angulata; EPI, Epinephrine; RT-PCR, Real time-polymerase chain reaction; L-DOPA, l-3,4-Dihydroxyphenylalanine; AC, Adenylate cyclase; PLC, Phospholipase C; PKA, Pro
GCH1 variants, tetrahydrobiopterin and their effects on pain sensitivity
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; CFA, Complete Freund’ Adjuvant; DAHP, 2,4-diamino-6-hydroxypyrimidine; DHPR, dihydropteridine reductase; l-DOPA, l-3,4-dihydroxyphenylalanine; DRG, dorsal root ganglia; GCH1, GTP cyclohydrolase 1; GTP, guanosine triphosphate; NAS, N-acetylserotonin; NO, n
Reverse microdialysis of a 5-HT2A receptor antagonist alters extracellular glutamate levels in the striatum of the MPTP mouse model of Parkinson’s disease
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; L-DOPA, L-3,4-dihydroxyphenylalanine; 5-HT, serotoninGlutamate; M100907; Microdialysis; Parkinsonism; MPTP; Serotonin
Influencing the monophenolase/diphenolase activity ratio in tyrosinase
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; l-Dopa, l-3,4-dihydroxyphenylalanine; TyrBm, tyrosinase from Bacillus megateriumTyrosinase; Bacillus megaterium; Rational design; Diphenol; Copper
5-HT1 receptor agonists for the treatment of L-DOPA-induced dyskinesia: From animal models to clinical investigation
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; 6-OHDA, 6-hydroxydopamine; AIMs, Abnormal involuntary movements; DA, Dopamine; L-DOPA, L-3,4-dihydroxyphenylalanine; LID, L-DOPA-induced dyskinesia; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Partkinson's disease6-OHDA; Dopamine; Serotonin; L
Pharmacological and genetic evidence for pre- and postsynaptic D2 receptor involvement in motor responses to nociceptin/orphanin FQ receptor ligands
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Amisulpride; Dopamine; D2 receptors; l-dopa; Nociceptin/orphanin FQ; PramipexoleJ-113397, 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H benzimidazol-2-one; l-dopa, l-3,4-dihydroxyphenylalanine; N/OFQ, nociceptin/orphani
Ambient illuminance, retinal dopamine release and refractive development in chicks
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; chicks; refraction; illuminance; light intensity; continuous light; outdoor light; dopamine; DOPACDOPAC, dihydroxyphenylacetic acid; l-DOPA, l-3,4-dihydroxyphenylalanine
Voltage-gated calcium channels and Parkinson's disease
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Ca2+, calcium ion; CaV, voltage-gated calcium channel; L-DOPA, L-3,4-dihydroxyphenylalanine; 6-OHDA, 6-hydroxydopamine; mRNA, messenger RNA; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PCR, polymerase chain reaction; RT, reverse transcription; SN,
Antityrosinase and antimicrobial activities of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; l-DOPA, l-3,4-dihydroxyphenylalanine; DMSO, dimethylsulfoxide; IC50, the inhibitor concentrations leading to 50% activity lost; MIC, the minimum inhibitory concentration; MBC, the minimum bactericidal concentration; KI, the equilibrium constant of the inh
First evidence of a potential antibacterial activity involving a laccase-type enzyme of the phenoloxidase system in Pacific oyster Crassostrea gigas haemocytes
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Phenoloxidases; Antibacterial activity; Vibrio; Bivalve; ImmunityPOs, phenoloxidases; HLS, haemocyte lysate supernatant; l-DOPA, l-3,4-dihydroxyphenylalanine; PPD, p-phenylenediamine; PTU, 1-phenyl-2-thiourea; DETC, diethyldithiocarbamate; CTAB, cethyltri
Dopamine release and molecular modeling study of some coumarin derivatives
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; PC12, pheochromocytoma; PKA, protein kinase A; CaMK II, Ca2+/calmodulin-dependent protein kinases II; L-DOPA, L-3,4-dihydroxyphenylalanine; TH, tyrosine hydroxylase; BuChE, butyrylcholinesterase; AD, Alzheimer’s disease; DA, dopamine; AMPH, amphetamine; P
Inhibitory effects of p-alkylbenzoic acids on the activity of polyphenol oxidase from potato (Solanum tuberosum)
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; PPO, polyphenol oxidase; l-DOPA, l-3,4-dihydroxyphenylalanine; DMSO, dimethylsulphoxide; IC50, the inhibitor concentrations leading to 50% activity lost; PBS, sodium phosphate buffer; Km, Michaelis–Menten constant; Vm, maximum velocityPotato; Polyphenol o
Influence of olfactory bulbectomy on maternal behavior and dopaminergic function in nucleus accumbens in mice
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; ANOVA, analysis of variance; l-DOPA, l-3,4-dihydroxyphenylalanine; MPOA, medial preoptic area; NAc, nucleus accumbens; NAcC, nucleus accumbens core; NAcSh, nucleus accumbens shell; NGS, normal goat serum; OB, olfactory bulb; OBX, olfactory bulbectomy; PBS
Nest building performance following MPTP toxicity in mice
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; DA, dopamine; DAT, dopamine transporter; DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanilic acid; l-DOPA, l-3,4-dihydroxyphenylalanine; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; SEM, standard error of the mean; TH,
Inhibitory effects of α-cyano-4-hydroxycinnamic acid on the activity of mushroom tyrosinase
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; HCCA, α-cyano-4-hydroxycinnamic acid; DMSO, dimethyl sulfoxide; l-DOPA, l-3,4-dihydroxyphenylalanine; Tyr, l-tyrosine; IC50, the inhibitor concentrations leading to 50% activity lostMushroom tyrosinase; Monophenolase activity; Diphenolase activity; α-Cyan
A case of 6-pyruvoyl-tetrahydropterin synthase deficiency demonstrates a more significant correlation of l-Dopa dosage with serum prolactin levels than CSF homovanillic acid levels
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; BH4, tetrahydrobiopterin; 5-HTP, 5-hydroxytryptophan; HVA, homovanillic acid; l-Dopa, l-3,4-dihydroxyphenylalanine; PTPS, 6-pyruvoyl-tetrahydropterin synthase6-Pyruvoyl-tetrahydropterin synthase deficiency; Prolactin; Tetrahydrobiopterin; Homovanillic aci
Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; DMSO, dimethylsulfoxide; l-DOPA, l-3,4-dihydroxyphenylalanine; Tyr, l-tyrosine; IC50, the inhibitor concentrations leading to 50% activity lost; PDA, potato dextrose agar; CFU, colony forming unit; MIC, the minimum inhibitory concentration; MBC, the minim
Characterization of polyphenoloxidase (PPO) and total phenolic contents in medlar (Mespilus germanica L.) fruit during ripening and over ripening
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; PPO, polyphenoloxidase; PHPPA, (p-hydroxyphenyl) propionic acid; 4-MC, 4-methylcatechol; DAFB, day after full bloom; PMSF, phenylmethylsulfonyl fluoride; l-DOPA, l-3,4-dihydroxyphenylalanine; MBTH, 3-methyl-2-benzothiazolinone hydrazone; DMF, dimethylform
Inhibitory effects of phloridzin dihydrate on the activity of mushroom (Agaricus bisporus) tyrosinase
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; PPO, polyphenol oxidase; DMSO, Dimethylsulfoxide; Tyr, tyrosine; l-DOPA, l-3,4-dihydroxyphenylalanine; IC50, the inhibitor concentration leading to 50% activity lostMushroom tyrosinase; Diphenolase activity; Inhibition; Phloridzin dihydrate
Characterization of phenoloxidase activity in Sydney rock oysters (Saccostrea glomerata)
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; CPIC, complete protease inhibitor cocktail; DDC, DOPA decarboxylase; FSW, sterile filtered sea water; HBHZ, m-hydroxybenzylhydrazine; HL, hemolymph lysate; 4HA, hydroquinine monomethyl ether; LPS, lipopolysaccharide; l-DOPA, l-3,4-dihydroxyphenylalanine;
Induction of phenoloxidase and other immunological activities in Sydney rock oysters challenged with microbial pathogen-associate molecular patterns
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; Sydney rock oyster (Saccostrea glomerata); Zymosan; LPS; Phenoloxidase; PhagocytosisLPS, lipopolysaccharide; FSW, sterile filtered sea water; L-DOPA, l-3,4-dihydroxyphenylalanine; 4HA, hydroquinine monomethyl ether; MBTH, 3-methyl-2-benzothiazolinone hydr
Chronic 3,4-dihydroxyphenylalanine treatment induces dyskinesia in aphakia mice, a novel genetic model of Parkinson’s disease
Keywords: L-DOPA، L-3،4-دی هیدروکسی فنیل آلانین; DR, dopamine receptor KW-6002 (E)-1,3-diethyl-8-(3,4-dimethoxy)-7-methylxanthine; l-DOPA, l-3,4-dihydroxyphenylalanine; LID, l-DOPA-induced dyskinesia; PD, Parkinson’s disease; PPN, pedunculopontine nucleus; SN, substantia nigra; ZI, zona incerta; WT, wil