Keywords: IL1β, interleukin 1β; TXNIP, thioredoxin-interacting protein; ER, endoplasmic reticulum; NLRP, NOD-like receptor; PERK, protein kinase RNA-like ER kinase; IRE, inositol requiring enzyme; Atg7, autophagy-related gene; LC3, light chain 3; eIF2a, eukaryotic
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Study of autophagy-related protein light chain 3 (LC3)-II expression levels in thyroid diseases
Keywords: LC3, light chain 3; PTC, papillary thyroid cancerAutophagy-related protein light chain 3 (LC3)-II; Papillary thyroid cancer; Autophagy
Resveratrol regulates autophagy signaling in chronically ischemic myocardium
Keywords: 23; 29; 31.2; 38.2ACC, regular diet control; ATG 12-5, autophagy-related-gene 12-5 conjugate; HCC, high cholesterol control; HCRV, high cholesterol plus resveratrol; LAMP, lysosome-associated membrane protein; LC3, light chain 3; mTOR, mammalian target of
SB216763, a selective small molecule inhibitor of glycogen synthase kinase-3, improves bleomycin-induced pulmonary fibrosis via activating autophagy
Keywords: Autophagy; Pulmonary fibrosis; SB216763; Protein interactionBcl-2, B-cell lymphoma 2; BLM, bleomycin; ECM, extracellular matrix; GSK3, glycogen synthase kinase-3; IL-17A, interlukin-17A; LAMP-1, lysosome-associated membrane protein 1; LC3, light chain 3;
The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice
Keywords: 3-MA, 3-methyladenine; ANOVA, analysis of variance; BBB, blood–brain barrier; CCA, common carotid artery; EDTA, ethylenediaminetetraacetic acid; GFAP, glial fibrillary acidic protein; IGF, insulin-like growth factor; LC3, light chain 3; MCA, middle cerebr
Parkin Co-Regulated Gene is involved in aggresome formation and autophagy in response to proteasomal impairment
Keywords: 3-MA, 3-methyladenine; AV, autophagic vesicle; BSA, bovine serum albumin; ER, endoplasmic reticulum; FBS, foetal bovine serum; LB, Lewy body; LC3, light chain 3; MT, microtubule; MTOC, microtubule organising centre; PACRG, Parkin Co-Regulated Gene; PD, Pa
p53 Mediates autophagy activation and mitochondria dysfunction in kainic acid-induced excitotoxicity in primary striatal neurons
Keywords: p53; kainic acid; excitotoxicity; autophagy; mitochondriaEDTA, Ethylenediaminetetraacetic acid; KA, Kainic acid; LC3, light chain 3; LDH, lactate dehydrogenase; PFT-α, pifithrin-alpha; PFT-μ, pifithrin-mu; PIGs, p53-induced genes; 3-MA, 3-methyladenine; R
Exacerbation of ischemia-induced amyloid-β generation by diabetes is associated with autophagy activation in mice brain
Keywords: Aβ, amyloid-β; AD, Alzheimer's disease; avd, autophagy-like vacuoles containing electron-dense material; CCAO, occlusion of the common carotid artery; DM, diabetes mellitus; EM, electron microscopy; LC3, light chain 3; STZ, streptozotocin; PGL, plasma glu
Nutrient control of macroautophagy in mammalian cells
Keywords: LC3, light chain 3; GATE16, golgi-associated ATPase enhancer of 16 kDa; GABARAP, γ-aminobutyric-acid-type-A-receptor-associated protein; mTOR, mammalian target of rapamycin; DPPIV, Dipeptidyl peptidase IV; MAP, multiple antigen peptide; IVC, isovaleryl-l-