Keywords: AEC; apical epithelial cap; AGP; anterior gradient protein; BDNF; brain-derived neurotrophic factor; Cnox-2; paraHox gsx homologue gene; DUOX; dual oxidase; EGR; early growth response; ERK; extracellular signal-regulated kinase; FGF; fibroblast growth fac
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Keywords: ATRX; beta-catenin; DAXX; LEF1; p53; pancreatic ductal adenocarcinoma; pancreatic neuroendocrine tumor; Smad4; solid-pseudopapillary neoplasm; solitary fibrous tumor; STAT6
Bovine pituitary homeobox 2 (PITX2): mRNA expression profiles of different alternatively spliced variants and association analyses with growth traits
Keywords: SNP; single nucleotide polymorphism; CNV; copy number variation; PITX2; pituitary homeobox 2; PITX; paired-like homeodomain transcription factor; PITX2-V1; PITX2-variant 1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; NCBI; National Center of Biotechn
Inhibition of hepatocellular carcinoma tumorigenesis by curcumin may be associated with CDKN1A and CTGF
Keywords: TFs; transcription factors; miRNAs; microRNAs; HCC; hepatic cancer; DEGs; differentially expressed genes; KEGG; Kyoto Encyclopedia of Genes and Genomes; PPIs; protein-protein interactions; OS; overall survival; NGS; next generation sequencing; MATHT; Mult
Epithelial mesenchymal transition Transcription Factor (TF): The structure, function and microRNA feedback loop
Keywords: SNAIL; Snail family transcriptional repressor; ZEB; Zinc finger E-box binding homeobox; BMP1; Bone Morphogenetic protein1; TWIST; twist family bHLH transcription factor 1; GSC; goosecoid hemeobox; TGF-β; transforming growth factor beta; NPC; nasopharynge
An integrated study on TFs and miRNAs in colorectal cancer metastasis and evaluation of three co-regulated candidate genes as prognostic markers
Keywords: CRC; colorectal cancer; GRN; gene regulatory network; DEG; differentially expressed gene; TFs; transcription factors; DETF; differentially expressed transcription factor; miRNAs; micro-RNAs; DEmiR; differentially expressed miRNA; GO; gene ontology; Colore
Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway
Keywords: Agmatine; Akt; HT22; Ketamine; Neuroprotection; p70S6 kinase; PSD95; 4E-BPs; 4E binding proteins; ANOVA; analysis of variance; DMEM; Dulbecco's Modified Eagle Medium; ECT; electroconvulsive therapy; CUS; chronic unpredictable stress; FST; forced swim test
Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination
Keywords: RNA-Seq; Gonadal development; Transcriptional regulation; Lef1; Testis; Ovary;
Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model
Keywords: Cancer stem cells; PEITC; EpCAM; Oct4; Xenograft model; bFGF; basic fibroblast growth factor; EpICD; intracellular domain of EpCAM; FHL2; four and one-half LIM domains protein 2; GSK-3β; glycogen synthase kinase-3 beta; Lef1; lymphoid enhancer-binding fa
Original ArticleBruceine D inhibits hepatocellular carcinoma growth by targeting β-catenin/jagged1 pathways
Keywords: BD; Hepatocellular carcinoma; β-catenin; Jagged1; Wnt/Notch crosstalk; Sorafenib; HCC; hepatocellular carcinoma; BD; bruceine D; APC; adenomatous polyposis coli; GSK3β; glycogen synthase kinase-3β; LEF1; lymphoid enhancer binding factor 1; TCF4; T-cell
Expression and colocalization of β-catenin and lymphoid enhancing factor-1 in prostate cancer progression
Keywords: β-Catenin; LEF1; Multispectral imaging; Prostate cancer; Metastasis; Immunohistochemistry
Cell-autonomous requirement for TCF1 and LEF1 in the development of Natural Killer T cells
Keywords: TCF1; LEF1; NKT cells
microRNA regulation of Wnt signaling pathways in development and disease
Keywords: Wls; wntless; Porc; porcupine; HSPG; heparin sulfate proteoglycans; ARF; ADP-Ribosylation Factor; Dsh/Dvl; disheveled; DIX; disheveled Axin domain; PDZ; postsynaptic density 95, discs large, zonula occludens-1; DEP; Dvl, Egl-10, Pleckstrin; LRP5/6; low-de
Expression of LEF1 is an independent prognostic factor for patients with oral squamous cell carcinoma
Keywords: immunohistochemistry; LEF1; oral squamous cell carcinoma; prognosis
Identification of HDAC4 as a target of γ-catenin that regulates the oncogenic K-Ras-mediated malignant phenotype of Rat2 cells
Keywords: γ-Catenin; HDAC4; Lef1; Oncogenic K-Ras; Rat2 fibroblast cells;
Nemo-like kinase, a multifaceted cell signaling regulator
Keywords: NLK; Nemo-like kinase; IL-6; intereukin-6; MAPK; mitogen activated protein kinase; ERK; extracellular-signal regulated kinase; Pro; proline; Ser; serine; Thr; threonine; C. elegans; Caenorhabditis elegans; POP-1; Posterior pharynx defect protein 1; LEF1;
Hairless down-regulates expression of Msx2 and its related target genes in hair follicles
Keywords: HR; Msx2; Hair follicle; Hairpoor; Lef1; Foxn1
NLF2 gene expression in the endometrium of patients with implantation failure after IVF treatment
Keywords: ANGPTL; angiopoietin-like protein 1; APCR; activated protein C resistance; ART; assisted reproductive technology; DKK1; Dickkopf-related protein 1; ECM; extracellular matrix; EG-VEGF; endocrine gland-derived vascular endothelial growth factor; GAPDH; glyc
Towards the elucidation of the regulatory network guiding the insulin producing cells' differentiation
Keywords: NGN3 (NEUROG3); neurogenin3; ESCs; Embryonic Stem Cells; TFBS; Transcription Factor Binding Sites; TFs; Transcription Factors; AP4 (TFAP4); Activating enhancer-binding Protein 4 (Transcription Factor AP-4); WISP1; WNT-Induced Secreted Protein 1; CTGF; Con
5-Aza-2′-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-β-catenin expression
Keywords: Renal cell carcinoma; LEF1; β-catenin; DAC; PTX
β-Catenin/LEF1 activated enamelin expression in ameloblast-like cells
Keywords: Enamelin; Wnt/β-catenin; LEF1; Amelogenesis imperfecta; Tooth development
Wnt/Lef1 signaling acts via Pitx2 to regulate somite myogenesis
Keywords: Chicken embryo; Wnt signaling; Myogenesis; Lef1; Pitx2; Proliferation;
Role of Lef1 in sustaining self-renewal in mouse embryonic stem cells
Keywords: embryonic stem cells; Wnt signaling; β-catenin; Lef1; Oct4; Nanog
Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription
Keywords: Pax3; Lef1; β-Catenin; Transcription; Wnt-signalling; Cooperative interaction
Gene expression analysis of canonical Wnt pathway transcriptional regulators during early morphogenesis of the facial region in the mouse embryo
Keywords: Wnt signalling; Branchial arches; Tcf1; Lef1; Tcf3; Tcf4; Beta-cantenin; Facial development
Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction
Keywords: Beta-catenin; Notch1; NICD; HES1; LEF1; Osteogenesis
Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells
Keywords: HSC; Ki-67; Lef1; Pitx2; Tcf1; TWS119; Wnt
Collagen 11a1 is indirectly activated by lymphocyte enhancer-binding factor 1 (Lef1) and negatively regulates osteoblast maturation
Keywords: Lef1; Wnt; Beta-catenin; Collagen 11a1; VO; V1b; Osteoblasts
Genetic analysis and functional evaluation of the C/T(â318) and A/G(â1661) polymorphisms of the CTLA-4 gene in patients affected with Graves' disease
Keywords: CTLA-4; Graves' disease; Association; Promoter polymorphisms; LEF1; MEF2;
Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland
Keywords: Lef1; Mammary gland; TOPGAL; Wnt signaling; Hedgehog pathway;