
R468A mutation in perfringolysin O destabilizes toxin structure and induces membrane fusion
Keywords: تجمع لیپوزوم; DLS; dynamic light scattering; DOPC; 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; GST-PFO; glutathione-S-transferase-tagged wild type perfringolysin O; GST-PFOR468A; glutathione-S-transferase-tagged R468A perfringolysin O; HDX-MS; hydrogen deuter