
Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice
Keywords: TKI; tyrosine kinase inhibitors; BCRP; breast cancer resistance protein; LC/MS/MS; liquid chromatography-tandem mass spectroscopy; MDR; multi-drug resistance; 5,7-DMF; 5,7-dimethoxyflavone; P-gp; P-glycoprotein; EHC; enterohepatic cycling; Tyrosine kinase