Keywords: COPD; Budesonide; Formoterol fumarate dihydrate; Glycopyrronium; Co-suspension delivery technology; Pharmacokinetic; AE; adverse event; AUC0-â; area under the plasma concentration-time curve from time 0 to infinity; AUC0-12; area under the plasma
مقالات ISI (ترجمه نشده)
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Keywords: AMD; age-related macular degeneration; BCVA; best-corrected visual acuity; CGA; central geographic atrophy; CNV; choroidal neovascularization; DA; dark adaptation; LLQ; Low Luminance Questionnaire; logMAR; logarithm of the minimum angle of resolution; OCT
Keywords: FLG loss-of-function mutations; filaggrin; skin barrier; peanut sensitization; peanut allergy; environmental peanut exposure; dust; threshold; AD; Atopic dermatitis; CRD; Component-resolved diagnostics; FLG; Filaggrin; GEE; Penalized generalized estimatin
Keywords: Peanut; sensitization; allergy; environment; dust; aerosolized; airborne; saliva; hand; ELISA; validation; IOM; Inhalable occupational medicine; LLQ; Lower limit of quantitation; VPPE; Veratox polyclonal peanut ELISA;
Randomized study of the effects of Aerochamber Plus® Flow-Vu® on the efficacy, pharmacokinetics and safety of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler in patients with chronic obstructive pulmonary disease
Keywords: Co-suspension delivery technology; Formoterol fumarate dihydrate; Glycopyrronium; Metered dose inhaler; Spacer; Valved holding chamber; AE; adverse event; ANOVA; analysis of variance; AUC0-12; area under the curve from 0 to 12â¯h; BMI; body mass index;
Pharmacokinetics and safety of a single dose of the novel LAMA/LABA fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler, formulated using co-suspension delivery technology, in Japanese healthy subjects
Keywords: GFF MDI; Chronic obstructive pulmonary disease; Co-suspension delivery technology; LAMA/LABA; Pharmacokinetics; AE; adverse event; AUC0-12; area under the curve from 0 to 12â¯h; AUC0-t; area under the curve from 0 to time of the last measurable plasm
Safety and pharmacokinetics of budesonide/glycopyrronium/formoterol fumarate dihydrate metered dose inhaler (BGF MDI) in healthy adult subjects of Japanese descent
Keywords: Chronic obstructive pulmonary disease; Co-suspension delivery technology; ICS/LAMA/LABA; Western; Japanese; Triple fixed-dose combination; AE; adverse event; AUC0-12; area under the plasma concentration-time curve from 0 to 12â¯h; AUC0-â; area un
PKPD modelling of PR and QRS intervals in conscious dogs using standard safety pharmacology data
Keywords: AIC; Akaike information criterion; BSV; between subject variability; BLQ; below the limit of quantification; CV; cardiovascular; ECG; electrocardiogram; hERG; human ether-a-go-go-related gene channel; hCav1.2; human cardiac calcium channel; hNav1.5; human
A randomized, three-period crossover study of umeclidinium as monotherapy in adult patients with asthma
Keywords: Asthma; Fixed-dose combination; Muscarinic antagonist; Inhaled corticosteroid; Trough FEV1; Ae; amount of dose excreted unchanged in urine; AE; adverse event; ALT; alanine aminotransferase; AUC; area under the curve; BID; twice daily; bpm; beats per minut
Persistence of serogroup C antibody responses following quadrivalent meningococcal conjugate vaccination in United States military personnel
Keywords: ACIP; Advisory Committee on Immunization Practices; CDC; Centers for Disease Control and Prevention; DMSS; Defense Medical Surveillance System; DoD; Department of Defense; DoDSR; Department of Defense Serum Repository; ELISA; enzyme-linked immunosorbent a
Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: AÂ randomized trial
Keywords: IL-13; IL13Rα1; IL13Rα2; efficacy; safety; pharmacokinetics; pharmacodynamics; ACQ; Asthma Control Questionnaire; ADA; Anti-drug antibody; AE; Adverse event; ECLIA; Electrochemiluminescence immunoassay; Feno; Fraction of exhaled nitric oxide; FPE; Fluti
Combination of Vaniprevir With Peginterferon and Ribavirin Significantly Increases the Rate of SVR in Treatment-Experienced Patients With Chronic HCV Genotype 1 Infection and Cirrhosis
Keywords: Clinical Trial; Fibrosis; Direct-Acting Antiviral Agent; HCV; hepatitis C virus; LLQ; lower limit of quantification; mITT; modified intention-to-treat; P/R; peginterferon alfa and ribavirin; RAV; resistance-associated variants; RVR; rapid virologic respon
Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: A population and clonal analysis
Keywords: DAA; directly acting antiviral agent; HCV; hepatitis C virus; IC50; inhibitory concentration 50%; IU/mL; international units per milliliter; LLD; lower limit of detection; LLQ; lower limit of quantification; P/R; peginterferon alfa/ribavirin; SVR; sustain
Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: Examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia
Keywords: 5-HT2; 5-hydroxytryptamine; 6-OHDA; 6-hydroxydopamine; AM; allosteric modulator; AUC; area under curve; AUCINF; area under curve extrapolated to infinity; AUClast; area under curve from dosing to observation; AUMC; area under first moment curve; CL; total
Double-balloon enteroscopy as a rescue technique for failed direct percutaneous endoscopic jejunostomy when using conventional push enteroscopy (with video)
Keywords: BAE; balloon-assisted enteroscopy; BMI; body mass index; CVA; cerebrovascular accident; DBE; double-balloon enteroscopy; DPEJ; direct percutaneous endoscopic jejunostomy; GETA; general endotracheal anesthesia; LLQ; left lower abdominal quadrant; LUQ; left
Maximizing Opportunities and Avoiding Mistakes in Triple Therapy for Hepatitis C Virus
Keywords: Hepatitis C; Boceprevir; Telaprevir; Safety; Triple Therapy; ADVANCE; a new direction in HCV Care: a study of treatment naïve hepatitis C patient with telaprevir; DAA; direct-acting antiviral; eRVR; extended rapid virologic response; HCV; hepatitis C vir
Performance characteristics of the Cavidi ExaVir viral load assay and the ultra-sensitive P24 assay relative to the Roche Monitor HIV-1 RNA assay
Keywords: cp/mL; copies/mL; ELISA; enzyme-linked immunosorbent assay; FDA; US Food and Drug Administration; HIV; human immunodeficiency virus; LLQ; lower limit of quantitation; NPV; negative predictive value; PPV; positive predictive value; RT; reverse transcriptas
Efficacy and safety of fluticasone propionate hydrofluoroalkane inhalation aerosol in pre-school-age children with asthma: A randomized, double-blind, placebo-controlled study
Keywords: CFC; Chlorofluorocarbon; FP; Fluticasone propionate; HFA; Hydrofluoroalkane; ICS; Inhaled corticosteroid; ITT; Intent to treat; LLQ; Lower limit of quantification; MDI; Metered-dose inhaler; PEF; Peak expiratory flow; UC; Urinary cortisol; VHC; Valved hol
Assessment of Smoking Behaviors in the Home and Their Influence on Children's Passive Smoking: Development of a Questionnaire
Keywords: Cotinine; ETS; Parents; Outdoor Smoking; ABIS; All Babies in South-east Sweden; CCR; cotinine/creatinine ratio; CHC; child health clinic; CI; confidence interval; ETS; environmental tobacco smoke; LLQ; lowest level of quantification; OR; odds ratio; rs; S