GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death
Keywords: FCS, fetal calf serum; LMP, lysosomal membrane permeabilization; MMP, mitochondrial membrane potential; mTOR, mammalian target of rapamycin; PI3K, phosphatidylinositol-3-kinase; TFEB, Transcription Factor EB; zVAD.fmk, N-benzyloxycarbonyl-Val-Ala-Asp-fluo