Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr925
Keywords: Macrophage; PAI-1; FAK; Melanoma; Invasion; LRP1;
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The LRP1-independent mechanism of PAI-1-inudced migration in CpG-ODN activated macrophages
Keywords: CpG-ODN; Macrophages; PAI-1; LRP1; Migration;
Inverse relationship between raft LRP1 localization and non-raft ERK1,2/MMP9 activation in idiopathic dilated cardiomyopathy: Potential impact in ventricular remodeling
Keywords: α-2M; α-2 Macroglobulin; Ab; antibody; Cav-3; caveolin 3; cTnI; cardiac troponin I; ERK; extracellular signal-regulated kinase; p-ERK1,2; phospho-ERK; Flot-1; flotillin 1; IDCM; idiopathic dilated cardiomyopathy; LDL; low-density lipoprotein; LRP1; low-
t-PA acts as a cytokine to regulate lymphocyte-endothelium adhesion in experimental autoimmune encephalomyelitis
Keywords: Tissue-type plasminogen activator; ICAM-1; Endothelial cells; LRP1; Experimental autoimmune encephalomyelitis;
Agile delivery of protein therapeutics to CNS
Keywords: Aβ; amyloid β; Ab-InsR; antibodies against insulin receptor; Ab-TfR; antibodies against transferrin receptor; AD; Alzheimer's disease; Aerosol OT; bis-(2-ethylhexyl) sulfosucciate; ALS; amyotrophic lateral sclerosis; ApoB; apolipoprotein B; ApoE; apolip
Lipopolysaccharide downregulates CD91/low-density lipoprotein receptor-related protein 1 expression through SREBP-1 overexpression in human macrophages
Keywords: Lipopolysaccharide; Aggregated LDL; Human macrophages; LRP1; LDLR; SREBP-1; SREBP-2;
Association of polymorphisms in the LRP1 and A2M genes with Alzheimer’s disease in the Northern Chinese Han population
Keywords: Alzheimer’s disease; A2M; LRP1; Polymorphism
The role of astrocytes in amyloid β-protein toxicity and clearance
Keywords: Astrocytes; Amyloid β-protein; Apolipoprotein E; Clearance; Toxicity; Blood–brain barrier; LRP1
Interaction between intravenous immunoglobulin (IVIg) and the low-density lipoprotein receptor-related protein 1: A role for transcytosis across the blood brain barrier?
Keywords: Intravenous immunoglobulin; IVIg; LRP1; Endocytosis;
Los polimorfismos del gen LRP1 se asocian al riesgo prematuro de enfermedad cardiovascular en pacientes con hipercolesterolemia familiar
Keywords: ECVp; enfermedad cardiovascular prematura; HFh; hipercolesterolemia familiar heterocigótica; LRP1; proteÃna 1 relacionada con el receptor de lipoproteÃnas de baja densidad; SNP; polimorfismo de un solo nucleótido; Enfermedad cardiovascular; Polimorfis
Low-density lipoprotein receptor-related protein 1: A physiological Aβ homeostatic mechanism with multiple therapeutic opportunities
Keywords: Alzheimer's disease; Amyloid β-peptide; LRP1; Soluble LRP1 (sLRP1); sLRP1 fragments
Signaling through LRP1: Protection from atherosclerosis and beyond
Keywords: Atherosclerosis; Lipid metabolism; Cell signaling; Vascular smooth muscle cells; LRP1
Lead exposure increases levels of β-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice
Keywords: Lead; Alzheimer's disease; β-Amyloid; LRP1; Choroid plexus; APP transgenic mice
Apolipoprotein A-V; a potent triglyceride reducer
Keywords: TG; triglycerides; LPL; lipoprotein lipase; LDLr; LDL receptor; LRP1; LDLr-related protein 1; HSPG; heparin sulfate proteoglycans; Apolipoprotein A-V; Apolipoprotein A5; Plasma triglyceride metabolism; Lipoproteins; Lipoprotein lipase; Heparan sulfate pro
Extracellular proteases in epilepsy
Keywords: ADAM; a disintegrin and metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; CCI; controlled cortical impact; ECM; extracellular matrix; ECS; electroconvulsive shock; FH; complement inhibitor; GCD; granule cell disper
Angiotensin II-induced smooth muscle cell migration is mediated by LDL receptor-related protein 1 via regulation of matrix metalloproteinase 2 expression
Keywords: Smooth muscle cells; Migration; LRP1; Angiotensin II; Matrix metalloproteinase 2;
Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy
Keywords: Matrix metalloproteinase; Furin; LRP1; TIMP-2; Cell migration; Metastasis
Lead-induced accumulation of β-amyloid in the choroid plexus: Role of low density lipoprotein receptor protein-1 and protein kinase C
Keywords: Blood–CSF barrier; Lead or Pb; Aβ; LRP1; Choroid plexus; Protein kinase C; PKC-δ; Rottlerin
Immunohistochemical localization of low density lipoprotein receptor-related protein 1 and α2-Macroglobulin in retinal and choroidal tissue of proliferative retinopathies
Keywords: α2-Macroglobulin; LRP1; diabetes mellitus; sickle cell disease; ischemia; retina; choroid
Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression
Keywords: Aggregated LDL; LRP1; SREBP-1a; SREBP-1c; SREBP-2; Human VSMC
Identification of LRP1B-interacting proteins and inhibition of protein kinase Cα-phosphorylation of LRP1B by association with PICK1
Keywords: LDL receptor family; LRP1B; LRP1; PICK1; JIP; PDZ domain; Protein kinase C;
RAGE, LDL receptor, and LRP1 expression in the brains of SAMP8
Keywords: BBB; LDLR; LRP1; RAGE; SAM
MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1
Keywords: MicroRNA; LRP1; Cell migration; Tumor
Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance
Keywords: Lipoprotein metabolism; Low density lipoprotein receptor-related protein 1; LRP1; Insulin; Insulin resistance; Postprandial lipaemia
Increased β-amyloid levels in the choroid plexus following lead exposure and the involvement of low-density lipoprotein receptor protein-1
Keywords: Blood–CSF barrier; Pb; Aβ; LRP1; Choroid plexus; Blood–brain barrier; Alzheimer's disease
Minimization of the third domain of the LDL receptor-associated protein (RAP)
Keywords: RAP; Receptor-associated protein; LDLR; LRP1; VLDLR; Complement-type repeat; Domain;
Functional mimicry of the LDL receptor-associated protein through multimerization of a minimized third domain
Keywords: RAP; Receptor-associated protein; LRP1; Multimer; Avidity; Liver; Delivery; Targeting;
Slow endocytosis of the LDL receptor-related protein 1B: Implications for a novel cytoplasmic tail conformation
Keywords: LRP1B; LRP1; Endocytosis; Tumor suppressor;
Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway
Keywords: Lactoferrin; LRP1; Apoptosis; Osteoblast;
Sterol Regulatory Element-binding Protein-2 Negatively Regulates Low Density Lipoprotein Receptor-related Protein Transcription
Keywords: LRP1; SREBP-2; down-regulationLDL, low density lipoprotein; agLDL, aggregated LDL; LDLR, LDL receptor; SRE, sterol regulatory element; SREBP-2, sterol regulatory element binding protein; VSMC, vascular smooth muscle cells; LRP1, low density lipoprotein re
Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease
Keywords: Alzheimer's disease; LRP1; Meta-analysis; Brain pathology; Association study;
LRP1B functions as a receptor for Pseudomonas exotoxin
Keywords: Toxin; Receptor; LRP1; LRP1B; Pseudomonas; ADP-ribosylation;
Do clustered β-propeller domains within the N-terminus of LRP1 play a functional role?
Keywords: LRP1; low density lipoprotein receptor-related protein 1; LDLR; low density lipoprotein receptor; ER; endoplasmic reticulum; EGF; epidermal growth factor; RAP; receptor-associated protein; CHO; Chinese hamster ovary; endo H; endoglycosidase H; PNGaseF; pe