Keywords: Nitro compounds; Natural products; Pharmaceuticals; Stereoselective synthesis; Organocatalysis; Metal catalysis; Nitronates; Nitrile oxides; AIBN; azobisisobutyronitrile; AZADO; 2-azaadamantane-N-oxyl; 9-BBN; 9-borabicyclo[3.3.1]nonane; BINAP; 2,2â²-bis(
مقالات ISI (ترجمه نشده)
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Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship
Keywords: Cefiderocol; Siderophore; Siderophore cephalosporin; Multi-drug resistant Gram-negative pathogens; ESBL; extended-spectrum β-lactamase; MDR; multi-drug resistant; PG; protecting group; ACLE·HCl; (7-amino-3-chloromethyl-3-cephem-4-carboxylate p-methoxybe
Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential
Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c
Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective α1D adrenoceptor antagonists
Keywords: Phenoxyethylamine derivatives; Selective human α1D adrenoceptor antagonist; 3,4-Dihydro-2H-thiochromene 1,1-dioxide; Ligand-lipophilicity efficiency (LLE); AR; Adrenoceptor; BH3; borane; Boc2O; di-tert-butyl bicarbonate; t-BuXphos; 2-di-tert-butylphosp
Investigation of catalytic activity of new Co(II) phthalocyanine complexes in cyclohexene oxidation using different type of oxidants
Keywords: Phthalocyanine; Cobalt(II); Cyclohexene oxidation; Oxidant; m-Chloroperoxybenzoic acid
Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125
Keywords: DPP-4; Dipeptidyl peptidase IV; GLP-1; Glucagon-like peptide 1; SAR; Structure-activity relationship; AcOH; Acetic acid; DIBAL-H; Diisobutylaluminum hydride; Boc; tert-Butoxy carbonyl; TMSCN; Trimethylsilyl cyanide; TBAF; Tetrabutylammonium fluoride; mC
Advances in the Baylis-Hillman reaction-assisted synthesis of cyclic frameworks
Keywords: Baylis-Hillman reaction; Cyclic compounds; Heterocycles; Nucleophilic substitution; Ac; acetyl; AIBN; 2,20-azobisisobutyronitrile; Aq; aqueous; Ar; aryl; 9BBN; 9-borabicyclo[3.3.1]nonane; BINAP; 2,20-bis(diphenylphosphanyl)-1,10-binaphthyl; BF3·Et2O; b
Reactivity of fluorinated sulfur-containing heterocycles towards nucleophilic and oxidizing reagents
Keywords: Diels-Alder adducts of hexafluorothioacetone; Reaction with iso-propyl magnesium chloride; Oxidation; m-Chloroperoxybenzoic acid;
Synthesis of cis-3,4-diarylpiperidines and cis-3,4-diaryltetrahydropyrans
Keywords: m-Chloroperoxybenzoic acid; Boron trifluoride etherate; cis-3,4-Diarylpiperidines; cis-3,4-Diaryltetrahydropyrans; 3,4-Diarylpyridines;
New synthesis of cis-3,4-diaryl-1-tosylpyrrolidines
Keywords: 4-Aryl-1,2,5,6-tetrahydropyridines; 3-Arylpyrrolines; cis-3,4-Diarylpyrrolidines; Grignard addition; m-Chloroperoxybenzoic acid; Boron trifluoride etherate;
New synthesis of 3-arylpyrrolines
Keywords: 3-Arylpyrrolines; 4-Aryl-1,2,3,6-tetrahydropyridines; m-Chloroperoxybenzoic acid; Boron trifluoride etherate;
Spectroscopic investigations of intermediates in the reaction of cytochrome P450BM3–F87G with surrogate oxygen atom donors
Keywords: Cytochrome P450BM3; Stopped-flow; Compound I; Compound ES; Electron paramagnetic resonance; Iodosobenzene; m-Chloroperoxybenzoic acid
Use of monoterpenes, 3-carene and 2-carene, as synthons in the stereoselective synthesis of 2,2-dimethyl-1,3-disubstituted cyclopropanes
Keywords: Cyclopropane; Chiral; Carenes; AIBN; 2,2â²-azobisisobutyronitrile; CSI; chlorosulfonyl isocyanate; DBU; 1,8-diazabicyclo[4.3.0]undec-7-ene; DIBAL; diisobutylaluminium hydride; DMAP; 4-dimethylaminopyridine; IBX; o-iodoxybenzoic acid; Ipy2BF4; bis(pyridin