Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation
Keywords: Cancer; eIF4E; Protein synthesis; mRNA translation; Cap-binding inhibitor; eIF; eukaryotic translation initiation factor; 4E-BP; eF4E-binding protein; FP; fluorescence polarisation; m7G; N7-methyl guanosine; RRL; rabbit reticulocyte lysate;