
Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions
Keywords: 6′-sulfo-sLex, 6′-sulfated sialyl Lewis X (NeuAcα2–3(6S)Galβ1–4(Fucα1–3)GlcNAc; CD, cluster of differentiation; Fc, fragment crystalizable region of IgG; Ig, immunoglobulin; IL, interleukin; ITIM, immunoreceptor tyrosine-based inhibitory motif; mAb, monoc