دانلود مقالات ISI درباره Maximum Tolerated Dose (Mtd) + ترجمه فارسی

ابتکار شرکت جهانی دارو: یک رویکرد مبتنی بر شواهد برای تعریف حد بالائی از کاهش وزن بدن در مطالعات سمیت کوتاه مدت

A global pharmaceutical company initiative: An evidence-based approach to define the upper limit of body weight loss in short term toxicity studies

Keywords: 3Rs; replacement, reduction, refinement; NC3Rs; National centre for the replacement, refinement and reduction of animals in research; BWL; body weight loss; MTD; maximum tolerated dose; NHPs; non-human primates; 3Rs; Body weight loss (BWL); Maximum tolera

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

“The dose makes the poison”: Key implications for mode of action (mechanistic) research in a 21st century toxicology paradigm

Keywords: Kinetically-derived Maximum Dose (KMD); Maximum Tolerated Dose (MTD); Linear-No-Threshold (LNT); ADME; Saturated metabolism; Mode of action;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

A critical examination of the mode of action of quinacrine in the reproductive tract in a 2-year rat cancer bioassay and its implications for human clinical use

Keywords: Quinacrine; Contraception; Carcinogenicity bioassay (CaBio); Maximum tolerated dose (MTD); Chronic inflammation; Mode of action; Biological relevance;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

High tolerated paclitaxel nano-formulation delivered by poly (lactic-co-glycolic acid)-g-dextran micelles to efficient cancer therapy

Keywords: Dextran; Paclitaxel; Drug delivery; Maximum tolerated dose (MTD); Tumor therapy;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Maximum Tolerated Dose and Early Response - Results of a Phase I Trial of Paclitaxel and Cisplatin with Radiation Therapy in Carcinoma of the Cervix1

Keywords: Cisplatin; maximum tolerated dose (MTD); paclitaxel; phase I; uterine cervical neoplasm;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Development of quantitative structure–activity relationship (QSAR) models to predict the carcinogenic potency of chemicals: I. Alternative toxicity measures as an estimator of carcinogenic potency

Keywords: Carcinogenic potency; Toxicity Prediction by Komputer Assisted Technology (TOPKAT); Cancer Potency Database (CPDB); Lethal Dose (LD50); Maximum Tolerated Dose (MTD); Oral Slope Factor (OSF); Tumor Dose (TD50); Mutagenicity; Octanol–Water Partition Coeffic

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Unifying CRM and EWOC designs for phase I cancer clinical trials

Keywords: Phase I cancer clinical trial; Maximum tolerated dose (MTD); Dose-limiting toxicity (DLT); Continual reassessment method (CRM); Escalation with overdose control (EWOC)

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

A review of whole animal bioassays of the carcinogenic potential of naphthalene

Keywords: Naphthalene; Animal bioassay; National Toxicology Program (NTP); Cancer; Carcinogenesis; Tumorigenesis; Cytotoxicity; Maximum tolerated dose (MTD); Inhalation studies

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Ackee (Blighia sapida) hypoglycin A toxicity: Dose response assessment in laboratory rats

Keywords: Ackee; Hypoglycin A; Dose response assessment; Acute toxic dose; Maximum tolerated dose (MTD)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه