دانلود مقالات ISI درباره Mcrc + ترجمه فارسی

واکنش زیستی تومورهای زنگ زده سرطان کولورکتال به درمان متوالی با پانیتومومب و بویازیوماب

Biologic Response of Colorectal Cancer Xenograft Tumors to Sequential Treatment with Panitumumab and Bevacizumab

Keywords: BB; bevacizumab-bevacizumab; BP; bevacizumab followed by panitumumab; CA9; carbonic anhydrase 9; CRC; colorectal cancer; DEGs; differentially expressed genes; EGFR; epidermal growth factor receptor; EPHA2; ephrin type-A receptor 2; FASN; fatty acid syntha

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

یک بررسی فاز دوم چند مرحله ای فاز دوم مطالعه اثربخشی و امکان سنجی 15 دقیقه تزریق پانیمومبوب پلاس ایرینوتانک برای سرطان کولورکتال متاستاتیک کریستال اکسپلی پلاتین و مقاوم در برابر ایزوالکتامین و کراس (تزریق کوتاه مدت آزمایش پانیومومب)

A Prospective, Multicenter Phase II Study of the Efficacy and Feasibility of 15-minute Panitumumab Infusion Plus Irinotecan for Oxaliplatin- and Irinotecan-refractory, KRAS Wild-type Metastatic Colorectal Cancer (Short Infusion of Panitumumab Trial)

Keywords: Anti-EGFR therapy; Convenience of outpatient; Fully humanized monoclonal antibody; Infusion-related reaction; mCRC;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

مینی بررسی شیمیدرمانی متیونومتری در سرطان متاستاتیک کولورکتال

Mini-reviewMetronomic chemotherapy in metastatic colorectal cancer

Keywords: Low dose; Metronomic chemotherapy; Metastatic colorectal cancer; CRC; colorectal cancer; mCRC; metastatic colorectal cancer; MTD; maximal tolerated dose; PFS; progression-free survival; OS; overall survival; TSP-1; thrombospondin-1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

کوانتومی تغییرات فشار خون در محفظه عروقی هنگام استفاده از یک کاتتر ضد رفلکس در طول شبیه سازی مایع در مقابل رادیو آمبولیزاسیون: یک سری موارد گذشته نگر

Quantification of Blood Pressure Changes in the Vascular Compartment When Using an Anti-Reflux Catheter during Chemoembolization versus Radioembolization: A Retrospective Case Series

Keywords: ANOVA; analysis of variance; DEE; drug-eluting embolic; HCC; hepatocellular carcinoma; ICC; intrahepatic cholangiocarcinoma; mCRC; metastatic colorectal carcinoma; SHAPD; systemic-hepatic artery pressure difference; SIS; Surefire Infusion System; TARE; tr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

توسعه همکاری داروی بیومارکرین در انکولوژی - 20 سال و شمارش

Drug-biomarker co-development in oncology - 20 years and counting

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; AKT; protein kinase B; ATP; adenosine triphosphate; cfDNA; circulating free DNA; CISH; chromogenic in-situ hybridization; CTC; circulating tumor cells; EGFR; epithelial growth factor receptor; EMT; epit

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

نشانگرهای مولکولی پیش آگهی و اهداف درمانی در سرطان متاستاتیک کولورکتال

Molecular markers of prognosis and therapeutic targets in metastatic colorectal cancer

Keywords: Colorectal; Targeted therapy; Metastatic colorectal cancer; Molecular markers; Biologic therapy; mCRC; metastatic colorectal cancer; CRC; colorectal cancer; OS; overall survival; DFI; disease free interval; MSI; microsatellite instability; CTC; circulatin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

پیگیری های بالینی و تصویربرداری پس از درمان ترانس آرترال برای بدخیمی های اولیه و ثانویه

Clinical and Imaging Follow-up Practices after Transarterial Therapy for Primary and Secondary Hepatic Malignancies

Keywords: Transarterial therapy; follow-up; hepatic malignancy; survey; IO; Interventional Oncology; IR; Interventional Radiology; LRT; locoregional therapy; SIR; Society of Interventional Radiology; CT; computed tomography; TACE; transarterial chemoembolization; c

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

محدودیت محاسبه فعالیت بر اساس سطح بدن برای رادیو آمبولیسازی متاستازهای کبدی در سرطان کولورکتال

Limitations of Body Surface Area-Based Activity Calculation for Radioembolization of Hepatic Metastases in Colorectal Cancer

Keywords: BSA; body surface area; CEA; carcinoembryonic antigen; DWL; whole-liver absorbed dose; mCRC; metastatic colorectal carcinoma; RECIST; Response Evaluation Criteria in Solid Tumors; REILD; radioembolization-induced liver disease; SPECT; single photon emissi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

بررسی آزمایشی پاسخ آنژیوژنیک به رادیو آمبولسیون یتریم-90 با میکروسپورهای رزین

Pilot Study of Angiogenic Response to Yttrium-90 Radioembolization with Resin Microspheres

Keywords: aFGF; acidic fibroblast growth factor; Ang-2; angiopoietin-2; bFGF; basic fibroblast growth factor; Conc; concentration; FGFR; fibroblast growth factor receptor; G-CSF; granulocyte colony-stimulating factor; GM-CSF; granulocyte-macrophage colony-stimulati

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease

Keywords: mCRC; KRAS mutation; PI3KCA mutation; FIr-B/FOx; Anti-VEGF; Anti-EGFR;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Observed benefit and safety of aflibercept in elderly patients with metastatic colorectal cancer: An age-based analysis from the randomized placebo-controlled phase III VELOUR trial

Keywords: Elderly; Aflibercept; mCRC; Second-line; VEGF-Trap; VELOUR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Cost-effectiveness of Trifluridine/tipiracil for Previously Treated Metastatic Colorectal Cancer in England and Wales

Keywords: Cost-utility; Economic model; mCRC; NICE; TAS-102;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

A Low-Toxicity DNA-Alkylating N-Mustard-Quinoline Conjugate with Preferential Sequence Specificity Exerts Potent Antitumor Activity Against Colorectal Cancer

Keywords: AST; aspartate transaminase; ALT; alanine transaminase; BUN; blood urea nitrogen; CBC; complete blood count; CRC; colorectal cancer; DMSO; dimethyl sulfoxide; D5W; 5% dextrose isotonic solution; FHC; fetal human colon epithelial cells; H&E; hematoxylin an

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study

Keywords: Activin receptor like-protein 1; Angiogenesis; Biomarker; mCRC; Prognostic;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Prognostic value of radiologically enlarged lymph nodes in patients with metastatic colorectal cancer: Subgroup findings of the randomized, open-label FIRE-3/AIO KRK0306 trial

Keywords: AJCC; American Joint Committee on Cancer; AP; alkaline phosphatase; BRAF; v-Raf murine sarcoma viral oncogene homolog B; CI; confidence interval; CRC; (colorectal cancer); CT; computed tomography; ECOG; Eastern Cooperative Oncology Group scale of performa

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of Primary Tumor Location on Second- or Later-line Treatment Outcomes in Patients With RAS Wild-type Metastatic Colorectal Cancer and All Treatment Lines in Patients With RAS Mutations in Four Randomized Panitumumab Studies

Keywords: mCRC; RAS mutant; RAS WT; Treatment lines; Tumor location;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Mutation and Methylation Analysis of Circulating Tumor DNA Can Be Used for Follow-up of Metastatic Colorectal Cancer Patients

Keywords: Biomarker; Digital droplet PCR; Liquid biopsies; mCRC; NPY;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Emerging paradigms in the treatment of liver metastases in colorectal cancer

Keywords: CRC; colorectal cancer; mCRC; metastatic colorectal cancer; CLM; colorectal liver metastases; SR; surgical resection; PVE; portal vein embolism; RFA; radiofrequency ablation; APC; adenomatous polyposis coli; LOH; loss of heterozygosity; EGFR; epidermal gr

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Bispecific antibodies for cancer therapy: A review

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; AE; adverse events; ALL; acute lymphoblastic leukemia; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; B-ALL; B-cell acute lymphoblastic leukemia; BiTES; Bi-sp

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

DNA mismatch repair in cancer

Keywords: 5-FU; 5-fluorouracil; bMMRD; Biallelic mismatch repair deficiency; CD28; cluster of differentiation 28; CIN; Chromosomal instable; CR; complete response; CRC; colorectal cancer; CTL; cytotoxic T-lymphocytes; CTLA-4; cytotoxic T lymphocyte antigen-4; DFS;

دانلود رایگان متن کامل مقاله ISI 77 صفحه سال انتشار : 2018 سفارش ترجمه

Polymerase proofreading domain mutations: New opportunities for immunotherapy in hypermutated colorectal cancer beyond MMR deficiency

Keywords: CRC; colorectal cancer; mCRC; metastatic CRC; CTLA4; cytotoxic T-lymphocyte-associated antigen 4; EGFR; epithelial growth factor receptor; HR; hazard ratio; MAP; mitogen-activated protein; mAb; monoclonal antibody; MEK; mitogen-activated protein/extracell

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Cytokine balance and behavioral intervention; findings from the Peer Approaches to Lupus Self-Management (PALS) project

Keywords: SLE; Systemic Lupus Erythematosus; PALS; Peer Approaches to Lupus Self-Management; PROs; patient reported outcomes; MCRC; Multidisciplinary Clinical Research Center; MUSC; Medical University of South Carolina; CDMP; Chronic Disease Self-Management Program

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet Digital PCR

Keywords: NSCLC; non-small cell lung cancer; TKI; tyrosine kinase inhibitor; PFS; progression-free survival; SARMS; Scorpion Amplification Refractory Mutation System; dPCR; digital polymerase chain reaction; ddPCR; picodroplet dPCR; mCRC; metastatic colorectal ca

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

STAT3 signaling mediates tumour resistance to EGFR targeted therapeutics

Keywords: STAT3; EGFR; Therapeutics; Cancer; EGF; Epidermal Growth Factor; EGFR; Epidermal Growth Factor Receptor; TGFα; Transforming Growth Factor-alpha; TGFβ; Transforming Growth Factor-beta; mAb; monoclonal antibody; TKI's; Tyrosine kinase inhibitors; mCRC; me

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ResearchHealth-related quality of life in patients with metastatic colorectal cancer, association with systemic inflammatory response and RAS and BRAF mutation status

Keywords: HRQoL; mCRC; Chemotherapy; RAS and BRAF mutation status; Inflammation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Efficacy, Tolerability, and Biomarker Analyses of Once-Every-2-Weeks Cetuximab Plus First-Line FOLFOX or FOLFIRI in Patients With KRAS or All RAS Wild-Type Metastatic Colorectal Cancer: The Phase 2 APEC Study

Keywords: Depth of response; Dosing schedule; Early tumor shrinkage; Erbitux; mCRC;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Quality of Life Analysis in Patients With RAS Wild-Type Metastatic Colorectal Cancer Treated With First-Line Cetuximab Plus Chemotherapy

Keywords: CRYSTAL; FOLFIRI; Global health status (GHS); mCRC; QoL;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewRAS Mutations as Predictive Biomarkers in Clinical Management of Metastatic Colorectal Cancer

Keywords: Cetuximab; KRAS; mCRC; NRAS; Panitumumab;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

FOLFIRI plus cetuximab in patients with liver-limited or non-liver-limited RAS wild-type metastatic colorectal cancer: A retrospective subgroup analysis of the CRYSTAL study

Keywords: Cetuximab; CRYSTAL; LLD; R0 resection; RAS; mCRC;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Prevalence of RAS mutations and individual variation patterns among patients with metastatic colorectal cancer: A pooled analysis of randomised controlled trials

Keywords: Panitumumab; mCRC; RAS prevalence; KRAS; NRAS; BRAF;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Original articleClinical endoscopyMetachronous colorectal cancers result from missed lesions and non-compliance with surveillance

Keywords: CRC; colorectal cancer; mCRC; metachronous CRC; PALGA; national pathology database; TNM; tumor, node, metastasis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

Keywords: FISH; Topoisomerase 1; Topoisomerase 2A; MMR; Chromosomal instability; Gene copy number; TOP1; gene symbol for the gene encoding topoisomerase 1; TOP2A; gene symbol for the gene encoding topoisomerase 2 alpha; CEN17; symbol for the chromosomal region enco

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Advances in patient-derived tumor xenografts: From target identification to predicting clinical response rates in oncology

Keywords: PDX; patient derived xenograft; CDX; cell line derived xenograft; CRD; clinically relevant dose; TIC; tumor initiating cell; NSG; NOD scid gamma; NSCLC; non-small cell lung cancer; CSC; cancer stem cell; SOC; standard of care; MTD; maximum tolerated dose;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

Keywords: Colorectal cancer; Prognosis; FISH; Topoisomerase 1; Gene copy number; Biomarker; CEN-20; centromere 20; CC; colon cancer; CI; confidence interval; CRC; colorectal cancer; DFS; disease free survival; 5FU; 5-fluorouracil; FFPE; formalin-fixed paraffin-embe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

microRNAs in colon cancer: A roadmap for discovery

Keywords: miRNA; microRNAs; CRC; Colorectal cancer; mCRC; Metastatic colorectal cancer; ncRNA; Non-coding RNA; ISH; In situ hybridization; FFPE; Formalin-fixed paraffin-embedded; NGS; Next Generation Sequencing; MSI-H; Microsatellite instability (high); MSI-L; Micr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Development of a Research Agenda for the Management of Metastatic Colorectal Cancer: Proceedings from a Multidisciplinary Research Consensus Panel

Keywords: AHRQ; Agency for Healthcare Research and Quality; CLM; colorectal liver metastases; CRC; colorectal cancer; DEBIRI; drug-eluting beads loaded with irinotecan; FLR; future liver remnant; FOLFIRI; folinic acid/5-fluorouracil/irinotecan [systemic chemotherap

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The role of cetuximab in converting initially unresectable colorectal cancer liver metastases for resection

Keywords: Conversion therapy; Resection; Cetuximab; MDT; mCRC;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2011 سفارش ترجمه