(5R)-5-hydroxytriptolide (LLDT-8), a novel immunosuppressant in clinical trials, exhibits potent antitumor activity via transcription inhibition
Keywords: LLDT-8, (5R)-5-hydroxytriptolide); MDR, multidrug-resistance; P-gp, P-glycoprotein; BrU, 5-bromouridine; HSP70, heat-shock protein 70(5R)-5-hydroxytriptolide; Triptolide; Transcription inhibition