Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2)
Keywords: MEKK2; MAP3K2; Kinase; Inhibitor; DMSO; dimethyl sulfoxide; MAPK; mitogen-activated protein kinase; MS; mass spectrometry; ATP; adenosine triphosphate; ADP; adenosine diphosphate; SAR; structure-activity relationship; SD; standard deviation; TR-FRET; time