
Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives
Keywords: CNS, central nervous system; AED, antiepileptic drug; NIH, National Institute of Health; SAR, structure–activity relationship; MES, maximal electroshock seizure; scMet, subcutaneous metrazol; ED50, dose effective in 50% of test subjects; TD50, dose neurot