دانلود مقالات ISI درباره کیناز Mevalonate + ترجمه فارسی

پیشرفت در ایمنی اولیه و بالینی در سال 2016

Advances in basic and clinical immunology in 2016

Keywords: کیناز Mevalonate; Immunology; primary immunodeficiency; whole-exome sequencing; hematopoietic stem cell transplantation; common variable immunodeficiency; severe combined immunodeficiency; hyper-IgE syndrome; AIP1; Actin-interacting protein 1; APDS; Activated PI3Kδ syndro

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

آیا داروهای مهار کننده مسیر مونولونات نیز سلول های بنیادی سرطانی را هدف قرار می دهند؟

Could drugs inhibiting the mevalonate pathway also target cancer stem cells?

Keywords: کیناز Mevalonate; Cancer stem-like cells; Mevalonate cascade; Ras; Rho; Stemness; Statins; Yap; ACAT; acetoacetyl-CoA transferase; acetyl-CoA; acetyl-coenzyme A; Arp2/3; actin-related protein 2/3 (actin polymerizing complex); BPs; bisphosphonates; CAMs; cell adhesion molec

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

طراحی، سنتز و مشخص نمودن مشتقات بیس فسفونات فلورسنت چند هدفه به عنوان مهارکننده های آنزیم چند منظوره در مسیر مونولانات

Multi-target-directed design, syntheses, and characterization of fluorescent bisphosphonate derivatives as multifunctional enzyme inhibitors in mevalonate pathway

Keywords: کیناز Mevalonate; FPP; farnesyl pyrophosphate; FPPS; farnesyl pyrophosphate synthase; GPP; geranyl diphosphate; HMG-CoA reductase; 3-hydroxy-3-methylglutaryl-CoA reductase; IPP; isopentenyl diphosphate; MDD; mevalonate 5-diphosphate decarboxylase, also known as mevalonate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

مهندسی متابولیسم مخمر - هدف قرار دادن متابولیسم استرول و تشکیل ترپنوئید

Yeast metabolic engineering - Targeting sterol metabolism and terpenoid formation

Keywords: کیناز Mevalonate; ABC; ATP-binding cassette; ADH; alcohol dehydrogenase; ADR; adrenodoxin reductase; ADX; adrenodoxin; ARE2; sterol acyltransferase; ARV1; mediator of sterol homeostasis; BTS1; GGPP synthase; CPR; cytochrome P450 reductase; CRT; carotenogenic (genes); CYP;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Integrated metabolomic and transcriptomic analyses revealed the distribution of saponins in Panax notoginseng

Keywords: کیناز Mevalonate; AACT; acetoacetyl-CoA acyltransferase; DS; dammarenediol-II synthase; DXPS; 1-deoxy-d-xylulose 5-phosphate synthase; DXPR; 1-deoxy-d-xylulose 5-phosphate reductoisomerase; FPS; farnesyl pyrophosphate synthase; FPP; farnesyl diphosphate; GDPS; gerenyl diph

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Lysophosphatidylcholine induces expression of genes involved in cholesterol biosynthesis in THP-1 derived macrophages

Keywords: کیناز Mevalonate; LPC; lysophosphatidylcholine; PCA; principal component analysis; FFA; free fatty acids; DMSO; dimethyl sulfoxide; FPKM; fragments per kilobase of transcript per million fragments mapped; RT-PCR; reverse transcription polymerase chain reaction; KEGG; Kyoto

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae

Keywords: کیناز Mevalonate; Mevalonate pathway; Isoprenoid; Mevalonate kinase; Phosphomevalonate kinase; Diphosphomevalonate decarboxylase; BMD; bisphosphomevalonate decarboxylase; DMD; diphosphomevalonate decarboxylase; GGPP; geranylgeranyl diphosphate; IP; isopentenyl phosphate; I

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria

Keywords: کیناز Mevalonate; Mevalonic aciduria; Mevalonate kinase deficiency; Mevalonic acid; Mevalonolactone; Mitochondrial function; Mitochondrial permeability transition; ACO; aconitase; Alm; alamethicin; BSA; bovine serum albumin; CAC; citric acid cycle; CCCP; carbonyl cyanide 3

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Pleiotropic effects of antitumour alkylphospholipids on cholesterol transport and metabolism

Keywords: کیناز Mevalonate; ABCA1; ATP-binding cassette transporter isoform A1; APL; alkylphospholipid; apoA1; apolipoprotein A1; CETP; cholesteryl ester transfer protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27; sterol 27-hydroxylase; DHCR7; 7-dehydrocholesterol reductase; ER; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Isoprenoid generating systems in plants - A handy toolbox how to assess contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthetic process

Keywords: کیناز Mevalonate; Ac-CoA; acetyl CoA; AACT; AcAC-CoA thiolase; CLM; clomazone (2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone); DMAPP; dimethylallyl diphosphate; DMNT; (3E)-4,8-dimethyl-1,3,7-nonatriene; DOXP; deoxyxylulose phosphate; DX; 1-deoxy-d-xylulose; DXK

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Quantitative metabolome, proteome and transcriptome analysis of midgut and fat body tissues in the mountain pine beetle, Dendroctonus ponderosae Hopkins, and insights into pheromone biosynthesis

Keywords: کیناز Mevalonate; Cytochrome P450; Mevalonate pathway; Midgut; Fat bodies; AACT; acetoacetyl-CoA thiolase; GO; gene ontology; GPPS/FPPS; geranyl diphosphate synthase/farnesyl diphosphate synthase; GGPPS; geranylgeranyl diphosphate synthase; HMG-R; 3-hydroxy-3-methylglutary

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2016 سفارش ترجمه

Quantification of mevalonate-5-phosphate using UPLC-MS/MS for determination of mevalonate kinase activity

Keywords: کیناز Mevalonate; MKD; mevalonate kinase deficiency; MK; mevalonate kinase; MVA; mevalonic acid; MVAP; mevalonate-5-phosphate; HIDS; hyperimmunoglobulinemia D and periodic fever syndrome; MA; mevalonic aciduria; Mevalonate kinase; MKD; Mevalonate kinase deficiency; HIDS; H

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Keywords: کیناز Mevalonate; Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Contents of therapeutic metabolites in Swertia chirayita correlate with the expression profiles of multiple genes in corresponding biosynthesis pathways

Keywords: کیناز Mevalonate; 7-DLGT; 7-deoxyloganetic acid glucosyl transferase; 8-HGO; 8-hydroxygeraniol oxidoreductase; AAC; acetyl-CoA carboxylase; AACT; acetoacetyl-CoA thiolase; ADH; arogenate dehydrogenase; ADT; prephenate dehydratase; C3H; p-coumarate 3-hydroxylase; C4H; trans

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis?

Keywords: کیناز Mevalonate; AACT; acetoacetyl-coenzyme A thiolase; Ac-CoA; acetyl-coenzyme A; AcAc-CoA; acetoacetyl-coenzyme A; ADP; adenosine diphosphate; ATP; adenosine triphosphate; CDP-ME; 4-diphosphocytidyl-2C-methyl-d-erythritol; CDP-MEP; 4-diphosphocytidyl-2C-methyl-d-erythri

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2012 سفارش ترجمه

Microbial production of isoprenoids

Keywords: کیناز Mevalonate; IPP; isopentenyl pyrophosphate; MEP; methylerythritol phosphate; DMAPP; dimethylallyl diphosphate; GPP; geranyl diphosphate; FPP; farnesyl diphosphate; MevT; Mevalonate “top” operon; MBIS; Mevalonate “bottom” operon; HMGS; HMG-CoA synthase; tHMGR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases

Keywords: کیناز Mevalonate; Mevalonate pathway; Metabolic pathway optimization; HMG-CoA Reductase; E. coli; Cofactor regeneration; Mevalonate kinase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular regulation of gonadotropin receptor expression: Relationship to sterol metabolism

Keywords: کیناز Mevalonate; Leutinizing hormone receptor; Mevalonate kinase; Post-transcriptional regulation; mRNA binding protein; Human chorionic gonadotropin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Mevalonate analogues as substrates of enzymes in the isoprenoid biosynthetic pathway of Streptococcus pneumoniae

Keywords: کیناز Mevalonate; Isoprenoid pathway; Mevalonic acid; Phosphomevalonic acid; Diphosphomevalonic acid; Mevalonate kinase; Phosphomevalonate kinase; Diphosphomevalonate decarboxylase; ProdrugATP, adenosine triphosphate; ADP, adenosine diphosphate; DPM-DC, diphosphomevalonate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei

Keywords: کیناز Mevalonate; Mitochondria; Glycosome; Isoprenoids; 3-Hydroxy-3-methyl-glutaryl Coenzyme A synthase; Mevalonate kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Statin synergizes with LPS to induce IL-1β release by THP-1 cells through activation of caspase-1

Keywords: کیناز Mevalonate; Autoinflammatory; Inflammation; Simvastatin; Mevalonate kinase; Interleukin-1β

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Regulation by SREBP-2 defines a potential link between isoprenoid and adenosylcobalamin metabolism

Keywords: کیناز Mevalonate; Mevalonate kinase; Cob(I)alamin adenotransferase; Cholesterol; SREBP; Atorvastatin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Regulation of luteinizing hormone receptor mRNA expression by a specific RNA binding protein in the ovary

Keywords: کیناز Mevalonate; Mevalonate kinase; LHR mRNA; Post-transcriptional regulation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

A novel post-transcriptional mechanism of regulation of luteinizing hormone receptor expression by an RNA binding protein from the ovary

Keywords: کیناز Mevalonate; LH receptor; Mevalonate kinase; Coding region binding protein; Post-transcriptional regulation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه