Keywords: MG، methylglyoxal; Ab, antibody; BSA, bovine serum albumin; CP, cortical perfusion; FBS, fetal bovine serum; GSH, reduced glutathione; MCA, middle cerebral artery; MG, methylglyoxal; MTT, 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyltetrazolium bromide; nNOS, neuronal nitric oxi
مقالات ISI MG، methylglyoxal (ترجمه نشده)
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Keywords: MG، methylglyoxal; AGEs, advanced glycation end products; G, glyoxal; MG, methylglyoxal; 3-DG, 3-deoxyglucosone; 3-DGal, 3-deoxygalactosone; 3-DLact, 3-deoxylactosone; 3-DPen, 3-deoxypentosone; Trios, triosone; Lact, the Amadori compound with lactose; Lact-H2O, the dehydrat
Keywords: MG، methylglyoxal; SOD, superoxide dismutase; TQ, thymoquinone; AGE, sadvanced glycation end products; MG, methylglyoxal; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; NBT, nitro blue tetrazolium; PMS, phenazine methosulfateSuperoxide dismutase; Glyca
Keywords: MG، methylglyoxal; AGEs, advanced glycation end products; Glo1, glyoxalase 1; Glo2, glyoxalase 2; GSH, reduced glutathione; GSSG, glutathione disulfide; MG, methylglyoxal; Pf, Plasmodium falciparumGlyoxalase; Inhibitor; Redox; Pharmacokinetics; Erythrocyte; Malaria
Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice
Keywords: MG، methylglyoxal; GLO1, glyoxalase1; MG, methylglyoxal; OFT, open-field test; BLA, basolateral amygdala; pBBG, S-bromobenzylglutathione cyclopentyl diesterMethylglyoxal; MG; Glyoxalase 1; GLO1; Anxiety
NAD+-linked alcohol dehydrogenase 1 regulates methylglyoxal concentration in Candida albicans
Keywords: MG، methylglyoxal; GCS1, γ-glutamylcysteine synthetase; GSH, glutathione; MG, methylglyoxal; NAD(P)+, nicotinamide adenine dinucleotide (phosphate); NADH, reduced nicotinamide adenine dinucleotide; Mgd, methylglyoxal dehydrogenase; rpm, revolutions per minute; HPLC, high pe
Impairment of the proteasome is crucial for glucose-induced lifespan reduction in the mev-1 mutant of Caenorhabditis elegans
Keywords: MG، methylglyoxal; AA, ascorbic acid; ABU, activated in blocked unfolded protein response; AGEs, advanced glycation end products; ER, endoplasmic reticulum; MG, methylglyoxal; NGM, nematode growth medium; PVDF, polyvinylidene difluoride; QPCR, quantitative polymerase chain
Methylglyoxal-induced stomatal closure accompanied by peroxidase-mediated ROS production in Arabidopsis
Keywords: MG، methylglyoxal; ABA, abscisic acid; [Ca2+]cyt, cytosolic free calcium concentration; FDA, fluorescein diacetate; H2DCF-DA, 2́,7́-dichlorodihydrofluorescein diacetate; JA, jasmonic acid; MAPK, mitogen-activated protein kinase; MeJA, methyl jasmonate; MG, methylglyoxal; NB
Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose
Keywords: MG، methylglyoxal; HG, high glucose; AP, argpyrimidine; GLO-1, glyoxalase 1; MG, methylglyoxal; AGEs, advanced glycation end-products; GLO-1-MCs, GLO-1-overexpressing mesangial cells; 8-OHdG, 8-hydroxy-deoxyguanosine; 4-HNE, hydroxyl-2-nonenal; PARP-1, poly(ADP-ribose) poly
Ambiguous effect of dendrimer PAMAM G3 on rat heart respiration in a model of an experimental diabetes – Objective causes of laboratory misfortune or unpredictable G3 activity?
Keywords: MG، methylglyoxal; AGEs, advanced glycation end products; DM, diabetes mellitus; ETS, electron transfer system; MG, methylglyoxal; OXPHOS, oxidative phosphorylation; PAMAM G3, generation 3 of poly(amido)amine dendrimer; RCR, respiratory control ratio; ROS, reactive oxygen s
Methylglyoxal has deleterious effects on thioredoxin in human aortic endothelial cells
Keywords: MG، methylglyoxal; AGEs, advanced glycation end products; 3-DG, 3-deoxyglucosone; GO, glyoxal; HAECs, human aortic endothelial cells; Met, metformin; MG, methylglyoxal; Prx, peroxiredoxin; ROS, reactive oxygen species; Trx, thioredoxinMethylglyoxal; Thioredoxin; Peroxiredox
Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: Sustained activation of the TRPA1 channel contributes to the pathogenesis of peripheral diabetic neuropathy
Keywords: MG، methylglyoxal; ANOVA, analysis of variance; CA, cinnamaldehyde; CHEM, Chembridge-5861528; DM, diabetes mellitus; DRG, dorsal root ganglion; 4-HNE, 4-hydroxynonenal; IENF, intraepidermal nerve fiber; MG, methylglyoxal; PDN, peripheral diabetic neuropathy; STZ, streptozot
Heat-shock protein 27 (Hsp27) as a target of methylglyoxal in gastrointestinal cancer
Keywords: MG، methylglyoxal; MG, methylglyoxal; Hsp25, heat-shock protein 25; Hsp27, heat-shock protein 27; AGE, advanced glycation end product; RGM, rat gastric mucosal; RIE, rat intestinal epithelial; YAMC, young adult mouse colon; MG-Hsp27, MG-modified Hsp27; ROS, reactive oxygen
Methylglyoxal has injurious effects on maturation of mouse oocytes, fertilization, and fetal development, via apoptosis
Keywords: MG، methylglyoxal; MG, methylglyoxal; COCs, cumulus–oocyte complexes; IVM, in vitro maturation; IVF, in vitro fertilization; ICM, inner cell mass; TE, trophectodermMethylglyoxal; Apoptosis; Oocyte maturation; Embryonic development
Influence of the microenvironment of thiol groups in low molecular mass thiols and serum albumin on the reaction with methylglyoxal
Keywords: MG، methylglyoxal; MG, methylglyoxal; AGEs, advanced glycation end products; RAGE, receptor for advanced glycation end products; HTA, hemithioacetal; CMC, S-(carboxymethyl)cysteine; CEC, S-(2-carboxyethyl)cysteine; HSA, human serum albumin; ASA, accessible surface areaMethy
Role of Gcn4 for adaptation to methylglyoxal in Saccharomyces cerevisiae: Methylglyoxal attenuates protein synthesis through phosphorylation of eIF2α
Keywords: MG، methylglyoxal; MG, methylglyoxal; eIF2α, the α subunit of translation initiation factor 2; TCA, trichloroacetic acidMethylglyoxal; S. cerevisiae; Stress; Adaptation; Translation initiation; eIF2α; Gcn4
Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats
Keywords: MG، methylglyoxal; STZ, streptozotocin; LIS, low-isoflavone soy protein; HIS, high-isoflavone soy protein; MG, Methylglyoxal; GSH, reduced glutathione; PPAR-γ, peroxisome proliferator–activated receptor-gamma; HDL, high-density lipoprotein.Soy isoflavones; Streptozotocin; D
Blockade of receptor for advanced glycation end product attenuates pulmonary reperfusion injury in mice
Keywords: MG، methylglyoxal; AGE, advanced glycation end product; ELISA, enzyme-linked immunosorbent assay; HMGB1, high-mobility group box-1; IR, ischemia and reperfusion injury; MG, methylglyoxal; NF, nuclear factor; PCR, polymerase chain reaction; PGD, primary graft dysfunction; RA
Pseudomonas aeruginosa contains multiple glyoxalase I-encoding genes from both metal activation classes
Keywords: MG، methylglyoxal; Glx, Glyoxalase; GlxI, Glyoxalase I; GlxII, Glyoxalase II; MG, methylglyoxal; GSH, glutathione; TSH, N1,N8-bis(glutathionyl)spermidine; PCR, polymerase chain reaction; TB, terrific broth; DPA, 2,6-pyridinedicarboxylic acid; IPTG, isopropyl β-d-thiogalacto
Hepatocyte susceptibility to glyoxal is dependent on cell thiamin content
Keywords: MG، methylglyoxal; TK, transketolase; GSH, glutathione; GSSG, oxidized glutathione; AGEs, advanced glycation end-products; MG, methylglyoxal; TPP, thiamin pyrophosphateThiamin; Glyoxal metabolism; Reactive oxygen species; Transketolase; Cytotoxicity; Advanced glycation end-
AGEs and methylglyoxal induce apoptosis and expression of Mac-1 on neutrophils resulting in platelet—neutrophil aggregation
Keywords: MG، methylglyoxal; AGEs, advanced glycation end products; BSA, bovine serum albumin; MG, methylglyoxal; PBMCs, peripheral blood mononuclear cells; PBS, phosphate-buffered saline; RAGE, receptor for advanced glycation end product; TF, tissue factorAGEs; Aggregation; Methylgl
Methylglyoxal suppresses TNF-α-induced NF-κB activation by inhibiting NF-κB DNA-binding
Keywords: MG، methylglyoxal; MG, methylglyoxal; GLO1, glyoxalase I; TNF, tumor necrosis factor; DMEM, Dulbecco's modified Eagle's medium; PBS, phosphate buffered saline; AGEs, advanced glycation end products; NLS, nuclear localization signalNF-κB; Methylglyoxal; Tumor necrosis factor
Short-chain aldehyde-derived ligands for RAGE and their actions on endothelial cells
Keywords: MG، methylglyoxal; AGE, advanced glycation endproducts; RAGE, receptor for AGE; Gcer, glyceraldehydes; Gcol, glycolaldehyde; SPR, surface-plasmon resonance; VEGF, vascular endothelial growth factor; CML, carboxymethyllysine; MG, methylglyoxal; 3-DG, 3-deoxyglucosone; EC, en
The effects of partial thiamin deficiency and oxidative stress (i.e., glyoxal and methylglyoxal) on the levels of α-oxoaldehyde plasma protein adducts in Fischer 344 rats
Keywords: MG، methylglyoxal; MG, methylglyoxal; TK, transketolase; TPP, thiamin pyrophosphate; RBC, red blood cells; ACF, aberrant crypt foci; AGEs, advanced glycation end-productsα-Oxoaldehydes; Methylglyoxal; Glyoxal; Oxidative stress; Thiamin; Protein adducts
Transgenic tobacco plants overexpressing glyoxalase enzymes resist an increase in methylglyoxal and maintain higher reduced glutathione levels under salinity stress
Keywords: MG، methylglyoxal; APx, ascorbate peroxidase; ASH, ascorbate; GPx, glutathione peroxidase; GR, glutathione reductase; GSH, reduced glutathione; GSSG, oxidized glutathione; GST, glutathione-S-transferase; Gly I, glyoxalase I; Gly II, glyoxalase II; MG, methylglyoxal; NADP, n