
IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme
Keywords: MGMT، O6-methylguanine-DNA methyltransferase; GBM, glioblastoma multiforme; IDH1, isocitrate dehydrogenase 1; MGMT, O6-methylguanine-DNA methyltransferase; MS-HRM, methylation sensitive high resolution melting; MS-MLPA, methylation sensitive multiplex ligation-dependent probe amplification; pGBMs, pr