Celecoxib inhibits mitochondrial O2 consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway
Keywords: ÎÏm; mitochondrial transmembrane potential; t-BHP; tert-butyl hydroperoxide; COX-2; cyclooxygenase-2; DCFDA; 2â²,7â²-dichlorofluorescein diacetate; DHE; dihydroethidium; GI50; dose of drug causing 50% inhibition of cell growth by MTT assay; G + M + S;