Keywords: Atherosclerosis; MKP-1; 23-Hydroxy ursolic acid; Monocytes; Macrophages;
مقالات ISI (ترجمه نشده)
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Keywords: Budesonide (PubChem CID: 5281004); Dexamethasone (PubChem CID: 5743); Hydrocortisone (PubChem CID: 5754); Prednisolone (PubChem CID: 5755); APC; allophycocyanin; BrdU; bromodeoxyuridine; CD; Crohn's disease; CFU; colony forming units; CXCL1; chemokine (
Keywords: AP-1; activator protein-1; AR; acute rejection; ATG; anti-thymocyte globulin; CAN; chronic allograft nephropathy; CBP; CREB-binding protein; CREB; cyclic AMP-responsive element-binding; DBD; DNA-binding domain; F2R; coagulation factor II receptor; FKBP; F
Keywords: PM; particulate matter; O3; ozone; COPD; chronic obstructive pulmonary disease; PM2.5-10; PM with an aerodynamic diameter 2.5-10 μm; PM2.5; PM with an aerodynamic diameter less than 2.5 μm; PM0.1; PM with an aerodynamic diameter less than 0.1 μm
Keywords: Macrophage activation; Lipid phosphatase; SHIP; PTEN; Protein tyrosine phosphatase; Shp2; PTPN22; PTP1B; SHP-1; Protein phosphatase; MKP-1
Keywords: AML; acute myeloid leukemia; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; BHA; butylated hydroxyanisole; C/EBP; CCAAT/enhancer binding proteins; CREB; cyclic AMP response element-binding proteins; CSF; cerebrospinal fluid; DUOX; dual
Rosmarinus officinalis essential oil: A review of its phytochemistry, anti-inflammatory activity, and mechanisms of action involved
Keywords: AA; Arachidonic Acid; ABST; 2,2â²-Azino-Bis(3-ethylbenzothiazoline-6-Sulfonic Acid); COX; Cyclooxygenase; DAMP; Damage-Associated Molecular Pattern; DMSO; Dimethyl Sulfoxide; DPPH; 2,2-Diphenyl-1-Picryl-Hydrazyl-Hydrate; EORO; Essential oil of Rosmarinus
Sinomenine inhibits lipopolysaccharide-induced inflammatory injury by regulation of miR-101/MKP-1/JNK pathway in keratinocyte cells
Keywords: Sinomenine; Lipopolysaccharide; miR-101; MKP-1; JNK signal pathway;
Stimulation of transient receptor potential M3 (TRPM3) channels increases interleukin-8 gene promoter activity involving AP-1 and extracellular signal-regulated protein kinase
Keywords: ATF2; c-Jun; ERK; Interleukin-8; MKP-1; TCF; TRPC6; TRPM3;
Mkp-1 cross-talks with Nrf2/Ho-1 pathway protecting against intestinal inflammation
Keywords: ARE; antioxidant response element; BHA; butylated hydroxyanisole; CD; Crohn's disease; ChIP; Chromatin immunoprecipitation; CHX; cycloheximide; COX-2; cyclooxygenase-2; DMSO; dimethyl sulfoxide; DSS; dextran sulfate sodium; Ho-1; heme oxygenase 1; IBD; in
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver
Keywords: Akt; Protein kinase B; AP-1; Activator protein-1; ASK1; Apoptosis signal-regulating kinase 1; ATF2; activating transcription factor 2;; ChIP; Chromatin immunoprecipitation;; DEN; Diethyl nitrosamine;; EGFR; Epidermal growth factor receptor; G6PDH; Glucose
Resveratrol: An overview of its anti-cancer mechanisms
Keywords: Resveratrol; Cancer metabolism; Nrf2; NLRP3; MAPK; NFkB; MKP-1; Autophagy;
A chlorogenic acid-phospholipid complex ameliorates post-myocardial infarction inflammatory response mediated by mitochondrial reactive oxygen species in SAMP8 mice
Keywords: Chlorogenic acid; Myocardial infarction; Reactive oxygen species; MKP-1; JNK;
Selectively targeting prostanoid E (EP) receptor-mediated cell signalling pathways: Implications for lung health and disease
Keywords: ASM; airway smooth muscle; BAL; bronchoalveolar; CHO; Chinese hamster ovary; COX; cyclooxygenase; EP; prostanoid E; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptors; GSK-3; glucogen synthase kinase-3; HMLC; human lung mast cel
A cannabinoid receptor 2 agonist reduces blood-brain barrier damage via induction of MKP-1 after intracerebral hemorrhage in rats
Keywords: Intracerebral hemorrhage; Cannabinoid receptor type 2; Neuroinflammation; Blood-brain barrier; MKP-1;
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways
Keywords: Dihydronortanshinone; Inflammation; LPS; Macrophage; AA; antimycin A; COX-2; cyclooxygenase-2; DNT; dihydronortanshione; iNOS; inducible nitric oxide synthase; IL-6; interleukin 6; LPS; lipopolysaccharide; MKP-1; mitogen-activated protein kinase phosphata
GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way
Keywords: Ad-GRK2; adenovirus expressing GPCR kinase-2; CD; contact dermatitis; CQ; chloroquine; DNCB; dinitrochlorobenzene; Gln; l-glutamine; GRK; GPCR kinase; MKP-1; MAPK phosphatase-1; siRNA; small interfering RNA;
Mkp-1 protects mice against toxin-induced liver damage by promoting the Nrf2 cytoprotective response
Keywords: ALT; alanine aminotransferase; ARE; antioxidant response element; AST; aspartate transaminase; BHA; butylated hydroxyanisole; CCl4; carbon tetrachloride; β-TrCP; β-transducin repeat-containing protein; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyde-3-p
Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect
Keywords: Theophylline; Cilomilast; Interleukin 8; COPD; Asthma; Chemokine; ASM; airway smooth muscle; MAPK; mitogen-activated protein kinase; MKP-1; MAPK phosphatase 1; PDE; phosphodiesterase; PP2A; protein phosphatase 2A; TNF; tumour necrosis factor;
The dataset describes: HIF-1 α expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages
Keywords: MKP-1; HIF-1α; p300; IL-1β; Bone marrow derived macrophages;
Clarithromycin inhibits TNF-α-induced MUC5AC mucin gene expression via the MKP-1-p38MAPK-dependent pathway
Keywords: MKP-1; MUC5AC; Clarithromycin; p38 MAPK;
MiR-212-3p inhibits LPS-induced inflammatory response through targeting HMGB1 in murine macrophages
Keywords: LPS; lipopolysaccharide; TLRs; Toll-like receptors; HMGB1; high mobility group box 1; miRNAs; microRNAs; mRNAs; messenger RNAs; siRNA; small interfering RNA; UTR; untranslated region; Mut; mutated; TNF-α; tumor necrosis factor-alpha; IL-6; interleukin-6;
Mitogen-activated protein kinase phosphatase 1 (MKP-1) in macrophage biology and cardiovascular disease. A redox-regulated master controller of monocyte function and macrophage phenotype
Keywords: ANP; Atrial natriuretic peptide; ARE; AU-rich elements; CS; catalytic sequence; DUSP; dual-specificity phosphatases; ERK; extracellular signal-regulated kinase; Grx; glutaredoxin; HA; hyaluronic acid; IFN; Interferon; IL; Interleukin; JNK; c-Jun N-termina
Archival ReportCingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression
Keywords: Anterior cingulate cortex; Chronic pain; Chronic stress; Depression; MAPK; MKP-1;
MKP-1 negatively regulates LPS-mediated IL-1β production through p38 activation and HIF-1α expression
Keywords: DUSPs; MKP-1; p38; HIF-1 α; IL-1β; Macrophages; BMDMs;
PARP inhibition protects mitochondria and reduces ROS production via PARP-1-ATF4-MKP-1-MAPK retrograde pathway
Keywords: PARP-1 inhibition; MKP-1; Dusp1; CREB; CREB2; ATF4; P38 MAPK; JNK; Cancer; Stem cells; Oxidative stress; ROS;
Prostaglandin E2 induces expression of MAPK phosphatase 1 (MKP-1) in airway smooth muscle cells
Keywords: Prostaglandins; Cell signalling; CREB; MKP-1; Airway smooth muscle; Inflammation;
TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators
Keywords: Corticosteroid insensitivity; TLR2; MKP-1; PP2A
p38α MAPK inhibits stretch-induced JNK activation in cardiac myocytes through MKP-1
Keywords: Cardiac myocytes; p38; JNK; Mechanical stretch; MKP-1; PP1;
cAMP-activated Nr4a1 expression requires ERK activity and is modulated by MAPK phosphatase-1 in MA-10 Leydig cells
Keywords: MAP kinase phosphatase; MKP-1; ERK1/2; Nr4a1; Nur77; Leydig cellsACTH, adrenocorticotropic hormone; cAMP, cyclic adenosine monophosphate; CHX, cycloheximide; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; LH, luteinizing hormone; MAPK, mitogen-activated
miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes
Keywords: LPS; lipopolysaccharide; CCL5; chemokine (C-C motif) ligand 5; FL; full length; SOCS-1; suppressor of cytokine signalling-1; MKP-1; mitogen-activated protein kinase phosphatase1; MRE; miRNA recognition elements; BS; binding site; ERK; extracellular regula
Critical role of MKP-1 in lipopolysaccharide-induced osteoclast formation through CXCL1 and CXCL2
Keywords: Osteoclasts; Chemokines; MKP-1; Lipopolysaccharide; Periodontal diseases;
Vibrio cholerae porin OmpU induces LPS tolerance by attenuating TLR-mediated signaling
Keywords: CCL; cysteine cysteine ligand; CXCR; cysteine-x-cysteine receptor; ELISA; enzyme linked immunosorbent assay; IL; interleukin; IRAK; interleukin-1 receptor associated kinase; LPS; lipopolysaccharide; MKP-1; MAPK phosphatase 1; MyD88; myeloid differentiatio
Regular ArticleInhibition of mitogen-activated protein kinase phosphatase-1 (MKP-1) increases experimental stroke injury
Keywords: Cerebral ischemia; MKP-1; MAPK;
A quinazoline-derivative compound with PARP inhibitory effect suppresses hypertension-induced vascular alterations in spontaneously hypertensive rats
Keywords: AngII; angiotensin II; AIF; apoptosis inducing factor; ASI; Aortic stiffness index; AP-1; activator protein 1; ASK1; apoptosis signal-regulating kinase 1; Crm1; chromosome region maintenance 1; DAB; 3,3â²-diaminobenzidine; DBP; diastolic blood pressure;
Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma
Keywords: Asthma; steroid resistance; corticosteroids; vitamin D; ChIP; Chromatin immunoprecipitation; DEX; Dexamethasone; GR; Glucocorticoid receptor; GRE; Glucocorticoid response element; MAPK; Mitogen-activated protein kinase; MED14; Mediator complex subunit 14;
The role of p38 signaling and poly(ADP-ribosyl)ation-induced metabolic collapse in the osteogenic differentiation-coupled cell death pathway
Keywords: AIF; apoptosis inducing factor; AP-1; activating protein-1; AP-2; activating protein 2; BMP2; bone morphogenetic protein 2; cMSC; chorion-derived mesenchymal stem cells; CTRL; control cells; DIFF; differentiating cells; ECAR; extracellular acidification r
Valproic acid suppresses lipopolysaccharide-induced cyclooxygenase-2 expression via MKP-1 in murine brain microvascular endothelial cells
Keywords: AREs; AU-rich elements; BBB; blood-brain barrier; C/EBPβ; CCAAT enhancer binding protein beta; CNS; central nervous system; COX-2; cyclooxygenase-2; HAT; histone acetyltransferase; HDAC; histone deacetylase; JNK; c-Jun N-terminal kinase; LPS; lipopolys
Cross talk between p38MAPK and ERK is mediated through MAPK-mediated protein phosphatase 2A catalytic subunit α and MAPK phosphatase-1 expression in human leukemia U937 cells
Keywords: MKP-1; MAPK phosphatase-1; PP2Acα; Protein phosphatase 2A catalytic subunit α; Caffeine; ERK; p38 MAPK; MKP-1; PP2A;
Asthma and lower airway diseaseObesity impairs apoptotic cell clearance in asthma
Keywords: Asthma; obesity; inflammation; macrophage; oxidative stress; steroid; ADAM; A disintegrin and metalloproteinase domain-containing protein; BMI; Body mass index; GCR; Glucocorticoid receptor; 4HNE; 4-Hydroxynonenal; MKP-1; Mitogen-activated protein kinas
Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation
Keywords: Asthma; viral respiratory tract infections; glucocorticoids; transcription factors; kinases; EC50; Median effective concentration; Emax; Maximal effective concentration; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; GR; Glucocorticoid receptor; GRE; Gl
Microinjection of sanguinarine into the ventrolateral orbital cortex inhibits Mkp-1 and exerts an antidepressant-like effect in rats
Keywords: Mkp-1; Sanguinarine; Ventrolateral orbital cortex; Antidepression; Microinjection;
MKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells
Keywords: Negative feedback effector; Cytokines; MKP-1; p38 MAPK; mRNA stability;
Combined α-tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets
Keywords: AP-1; activator protein-1; AT; α-tocopherol; AA; ascorbic acid; ERK; extracellular signal-regulated kinase; JNK; Jun N-terminal kinase; MAP; mitogen-activated protein; PCNA; proliferating cellular nuclear antigen; MDA; malondialdehyde; MEK; mitogen-activ
Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells
Keywords: AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride; ATM; ataxia telangiectasia mutated; ATR; AT- and Rad3-related; BRCA1; breast cancer susceptibility protein-1; CDKI; cyclin-dependent kinase inhibitor; DAF-DA; 4,5-diaminofluorescein diacetate; Cdk; cyclin-
Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease
Keywords: MKP-1; MAPK; Immunology; Mouse; Human; Inflammation
Back to your heart: Ubiquitin proteasome system-regulated signal transduction
Keywords: AF1/2; activation function 1/2 domains; AP-1; activator protein 1; AKT; protein kinase B; ARF-BP1; ARF binding protein 1; ATM; ataxia telangiectasia mutated; CARP1/2; caspase associated ring protein 1/2; CBP; CREB binding protein; CHIP; C-terminus of HSC7
Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by endoplasmic reticulum stress
Keywords: ATF6; activating transcription factor 6; BFA; brefeldin A; CaM; calmodulin; 15dPGJ2; 15-deoxy-Î12,14-prostaglandin J2; eIF2α; eukaryotic translation initial factor 2α; ER; endoplasmic reticulum; GAS; gamma-activated sequence; HAT; histone acetyltransfe
Crosstalk between cdk5 and MEK-ERK signalling upon opioid receptor stimulation leads to upregulation of activator p25 and MEK1 inhibition in rat brain
Keywords: BCA; bicinchoninic acid; cAMP; cyclic AMP; cdk5; cyclin-dependent kinase 5; ctx; cerebral cortex; DARPP-32; dopamine- and cAMP-regulated phosphoprotein of 32Â kDa; DMSO; dimethyl sulphoxide; ECL; enhanced chemiluminescence; ERK; extracellular signal-regul
Effects of chronic social defeat stress on MAP kinase cascade
Keywords: MAPK cascade; MKP-1; Social defeat stress; Resident-intruder paradigm; Depression;