Keywords: Cancer; Target therapy; Prodrug; MDR; Multidrug resistance; ROS; Reactive oxygen species; GSH; Glutathione; ADCs; Antibody-drug conjugates; ADEPT; Antibody-directed enzyme prodrug therapy; GDEPT; Gene-directed enzyme prodrug therapy; HIF; Hypoxia-inducibl
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Antibody-conjugated drug; Microwave-assisted hydrolysis; Drug antibody ratio; MMAE; Immunocapture mass spectrometry;
Keywords: 2-ME; 2-methoxyestradiol; CAIX; carbonic anhydrase IX; CSC; cancer stem cell; Dtx; docetaxel; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; FIH-1; factor inhibiting HIF-1; GSCs; glioma stem cells; HIF-1; hypoxia-inducible factor-1;
Keywords: Antibodies; Immunoconjugates; Immunotoxins; Ab; antibody; Ag; antigen; ADCC; antibody-dependent cell mediated cytotoxicity; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AKT; protein kinase B; APC; antigen-presenting cell; Apo2L/TRAIL; t
Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG
Keywords: ADC; antibody-drug conjugates; MMAE; monomethyl auristatin E; DAR; dhrug-to-antibody ratio; DTT; ditiothreitol; TCEP; (tris(2-carboxyethyl)phosphine; T-DM1; Trastuzumab emtansine; DM1; Mertansine; SMCC; Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-ca
Enhancing tumor response to targeted chemotherapy through up-regulation of folate receptor α expression induced by dexamethasone and valproic acid
Keywords: FR; folate receptor; Dexa; dexamethasone; VPA; valproic acid; ns; not significant; MMAE; monomethyl auristatin E; MGAF; β-galactosidase-responsive folate-monomethyl auristatin E conjugate; RT; room temperature; Folate receptor; Targeted drug delivery; De
Antibody-drug conjugates (ADCs): Potent biopharmaceuticals to target solid and hematological cancers- an overview
Keywords: Antibody-drug conjugates; Monoclonal antibodies; Anticancer; Drug resistance; Solid tumors; Hematological tumors; ADC; Antibody-Drug Conjugate; ALCL; Anaplastic Large Cell Lymphoma; ALL; Acute Lymphoblastic Leukemia; AML; Acute Myeloid Leukemia; BCMA; B C
A generic approach for simultaneous measurements of total antibody and cleavable antibody-conjugated drug by LC/MS/MS
Keywords: Antibody-drug conjugates; Antibody quantification; Drug Antibody Ratio; Antibody-conjugated drug; MMAE;
The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models
Keywords: ADC; antibody-drug conjugate; NHL; non-Hodgkin lymphoma; DLBCL; diffuse large B-cell lymphoma; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; MMAE; monomethyl auristatin E; SMCC; N-succinimidyl-4-(N-maleimidoe
Original ArticleThe two novel DLL4-targeting antibody-drug conjugates MvM03 and MGD03 show potent anti-tumour activity in breast cancer xenograft models
Keywords: DLL4; Antibody-drug conjugates; Tumour models; MMAE; DOX;
Targeting GPNMB with glembatumumab vedotin: Current developments and future opportunities for the treatment of cancer
Keywords: AE; Adverse Event; α-MSH; alpha-Melanocyte Stimulating Hormone; ADC; Antibody-Drug Conjugate; ASPS; Alveolar Soft Part Sarcoma; ASPSCR1; Alveolar Soft Part Sarcoma Chromosome Region Candidate 1; BMP-2; Bone Morphogenetic Protein-2; BRK; Breast Tumor Kina
Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates
Keywords: ADC; antibody-drug conjugate; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthalene; CBI; 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one; EDCI; N-ethyl-Nâ²-(3-dimethylaminopropyl)carbodiimide hydrochloride; MMAE; monomethyl auristatin E; PBD; p
Treatment of CD30-positive systemic mastocytosis with brentuximab vedotin
Keywords: 2-CdA; 2-chlorodeoxyadenosine; ADC; antibody-drug conjugate; ALCL; anaplastic large cell lymphoma; ANC; absolute neutrophil count; ASM; aggressive systemic mastocytosis; BM; bone marrow; CT; computed tomography; ECNM; European Competence Network on Mastoc
Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides
Keywords: ADC; antibody-drug conjugate; MMAE; monomethyl-auristatin-E; PAB; p-aminobenzyloxy; mAb; monoclonal antibody; PEG; poly(ethylene glycol); MWCO; molecular weight cut-off; HPLC; high performance liquid chromatography; Q-TOF; Quadrupole-time-of-flight; RP-HP
Autonomous navigation for a group of satellites with star sensors and inter-satellite links
Keywords: Autonomous navigation; Constellation; Star sensor; Visibility; CRLB; MMAE
Tracy-Widom distribution based fault detection approach: Application to aircraft sensor/actuator fault detection
Keywords: ADC; Analog-to-Digital Converter; EKF; Extended Kalman Filter; FDI; Fault Detection and Isolation; FTC; Fault Tolerant Control; GLR; Generalized Likelihood Ratio; IMM; Interacting Multiple-Model; KF; Kalman Filter; MMAE; Multiple model adaptive estimation