
Structure, function, aging and turnover of aggrecan in the intervertebral disc
Keywords: GAG, glycosaminoglycan; KS, keratan sulfate; HA, hyaluronic acid; IGD, interglobular domain; MMPs, metalloproteinases; CS, chondroitin sulfate; IVD, intervertebral disc; EGF, epidermal growth factor; CRP, complement regulatory protein; ECM, extracellular